Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
IQGAP1 PXN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15263019 22573807
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
UBAP2L BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 25185265
PA2G4 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
FLNA PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ITGB3 ITGAV â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214491 11546839
LZTS2 NINL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ESR1 YWHAB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
MLH1 PMS2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MLH1 AMOT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 17148452
ANLN FLNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN MYO6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN SYNPO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN MYH9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
BMI1 LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
EGFR LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24797263 31980649
EGFR FKBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
IGF1R ERBB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30898150 17307140
LZTS2 PLCG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARRB1 IGF1R â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33158816 21685939 15878855
CLTC MYO6 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
YWHAB IGF1R â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 9581554 6547842
NINL LZTS2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26638075 16189514 16713569
ARRB2 CLTC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
FLNA ARRB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17620599 16611986
ESR1 PA2G4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
EGFR PLCG1 â—¼   PHOSPHORYLATION ✅ + 0.84 0.84 Signor 1689310
PICALM PIK3C2A â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
PLCG1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 9020117 6805619
ESR1 MYH9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21182205
ESR1 FLNA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21182205
FLNA MYH9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
EGFR ARRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
ESR1 FKBP4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23403292 9222609
CLTB CLTC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
FLNA ARRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17984062 17620599 16611986
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
ATG7 MAP1LC3A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
EGFR ARRB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
RHOD ANKFY1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12577064 31871319 24102721
ARRB2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 24069330 28514442 17620599
EGFR CDK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18271526 15657067 24658140 31980649 23956138 25402006
PICALM CLTC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16491119 10436022
PLCG1 ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22973453 16273093 1683701 1676673
PMS1 MLH1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25502805 10748159 26496610 20004149 11292842 17148452 16189514
TRIM27 PIK3C2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22128329
EGFR PLCG1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
FLNA ITGB3 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
CLTC GAK â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
ARRB1 CLTC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
PMS2 MLH1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 20706999 33961781 25502805 30770470 10748159 22939629 26496610 16338176 18768816 17148452 11793469 14676842 11429708 10037723 15225546 12799449 12584560 17581638 25077178 20533529 16083711 11292842 20978114 22252508 18206974 12810663 19015241
ATG7 MAP1LC3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20562859 22170151 16303767
ERBB2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 55.0 1.0 Omnipath 18927589 17938195 10770932 17276342 17396146 11836499 17409144 29088738 19276355 26673326 19933706 28335434 20372791 7743995 11322924 19683496 27889260 17466630 14681223 12384528 12049736 7841526 12110582 25744022 18393321 15582998 19861462 14987992 20144215 17466629 16546994 19858290 15136770 14767478 20368335 25994202 10504341 1850698 15350223 24910099 9268380 15296723 8428596 24391510 18469858 8662825 20530684 11782384 15141014 15940258 12766774
CDK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 31980649 8360196 23956138 15901825 28150246 18271526 15657067 24658140 25402006 15302935
CDK1 NINL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20864540 21505454 20890132
CDK1 PIK3C2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12719431
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR PIK3C2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 31980649 10805725 11533253 24658140 25402006
EGFR PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 89.0 1.0 Omnipath 19901323 17081983 16273093 9207933 2472219 16497976 15592455 16126727 16713569 24797263 17389395 8578591 23331499 7991458 1689310 20068231 17570479 9176240 12803489 16153436 7993895 16038803 7805859 15864276 1708307 7682059 15144186 11983899 12601080 9756944 15212693 14568990 12061819 9020117 8885868 12648464 8657103 15951569 17016520 7693694
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
ESR1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24559156 16115928 16467118 17992604 19915977 15199112 21127199 21761336 21907803 20551150 11713584 1358436 20629094 18768663 19005469 9242384 20889718 10698518 16467117
ERBB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15173068
ERBB2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 16273093 1676673 1683701
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
IGF1R YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 12767520 10826997 12444011 21540285 15629149 17353931 19030972 14651979 17145710 16931767 9581554 12175651
VTN ITGAV â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7525578 7559467 17968485 9251239 7685013 9443892
ITGAV ITGB3 â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
ITGAV ITGB3 â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
VTN ITGAV â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23154389
VTN ITGB3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7525578 7559467 17968485 9251239 7685013 9443892
VTN ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16195248 11331280
MLH1 PMS1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 15703371 16612326 16697054 18157157 18406444 19847258 20478261
MLH1 PMS2 â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10882712 11900249 12556884 12648680 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17036055 17303408 17581638 17884153 18157157 18406444 18543256 18931676 19151707 19473888 19595721 19596235 19596236 19622404 19686080 19805513 19809470 19847258 20173781 20478261 21376743 22101340 22257761 22373527 22743550 22824526 23085398 24050180
MLH1 PMS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 25077178 17145710 10748159 17148452 11429708 18206974 19015241 16338176 20706999 15225546 25502805 19022408 12584560 26496610 14676842 16083711 11793469 10037723 11292842 22252508 17581638 12799449 18768816 20533529 31515488 20978114 12810663
MYH9 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
YWHAB PPP1CB â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
PMS1 MLH1 â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
PMS1 PMS1 â—¼   KO_DOWN_REGULATES ✅ - -7.89 7.88 PKG 28854368