PKG

Protein list:

NCOR2 HES1 MEF2C MAPK3 RBPJL MAP3K1 MAPK1 AKT1 MAP2K1 MAPK14 CAMK2G CAMK2A FLT3 RELA CHUK SIRT1 AR PGR GSTA2 NR0B1 CCR4 LHX3 GOLGA2 HNF1B NFIB CNOT2 PCK2 NFIC TP53BP1 SKIL ESR2 HNF4A DIO1 FHIP1B CTBP1 RUNX1 TEAD1 FOXQ1 E2F1 ATXN1L LHX4 AKAP8 SOX7 TLX2 TLX1 GATA1 GPS2 PAX7 CDKN1A ERG JARID2 PAX6 KDR NPRL3 KLF3 PAX8 FEV ACHE CCNB1 APP ELK3 PRDM1 IKZF1 MYOD1 SP7 GATA2 PAX2 RARA RANBP9 EN1 NFIA SOX10 LITAF CDK2 IRF4 FOXI1 IRF5 NFKBIB TBL1XR1 MMP1 KLF8 TBXT KLF5 FOXL1 DTX2 LHX2 RORC SOX2 BCOR CEBPB AFF2 C1D AP2M1 LHX1 NFE2L2 CBX6 HDAC1 ZBTB5 UGT2B17 RARB CCND1 PPM1D SOX15 CIR1 NR2F2 KLF15 CHAF1B NFIX HNRNPC SKI RNF113A CREBBP ABCA1 SF1 SAP30 PAX9 HMGCS2 TNIP2 HMGA1 NR4A2 IL12B SOX5 EP300 GATA3 ETV4 ATXN1 RXRG AHR SMG7 HIST1H4A NCOA3 TNIK SMARCA4 CAMK2B SUMO1 E2F4 NFKB1 UBE2I INPP5K ITGAV NFKBIA SRF NFKBIE SUMO3 TLX3 PRMT5 BACH2 FOS NR1H4 NR1H3 SPEN KPNA4 NR1H2 NR1D1 RARG HDAC10 NCOA6 TBL1X SP1 ARNT PPARG RXRB FOLR1 SUPT5H RXRA HESX1 HJURP HEY2 HDAC2 HDAC3 JUN H1-3 SIN3B RBPJ SNW1 SIN3A TBR1 SOX17 NCOR1 NR1I2 BTRC EGLN3 TNF EBP MMP9 CHEK2 NR3C1 POU2AF1 RHBDF2 TH CDKN2B MYCN FOXP1 PARN LPL CYP1A1 MDC1 SOX6 LEP IL1B NRD1 PPARD MBD3 CRH ALG3 PPARGC1A VEGFA IGF1 CIC PROS1 PIN1 GCM1 POU2F1 ESRRG ZBTB7A KMT2E THRA HDAC5

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Protein:

Eg: PBRM1 | ARID1A | BRCA1

Function:

Eg: Homologous recombination

Path:

Eg: SMC5 > DMC1 | PBRM1 > BRCA2

Relationship:

Full list of relationships

Graph tools:

Note this may take some time with > 30 proteins

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PKG Score Threshold: 0.8

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Source	Target	Relationship Type	Directed	Sign	DB Score	PKG Score	Database	References
ABCA1	RXRA	◼ PHYSICAL_INTERACTION			2.0	0.8	Reactome	18782758 21507939
ACHE	APP	◼ PHYSICAL_INTERACTION			801.0	0.8	STRING	36370105
AHR	CDKN1A	◼ TRANSCRIPTIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	12203118 24431146
AHR	VEGFA	◼ TRANSCRIPTIONAL_REGULATION	✅	-	2.0	0.8	Omnipath	17413038 19182260
AHR	TH	◼ TRANSCRIPTIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	22394336 19500377
AHR	MMP1	◼ TRANSCRIPTIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	19755661 15075337
AHR	MMP9	◼ TRANSCRIPTIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	19371443 19755661
AHR	AR	◼ POST_TRANSLATIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	19815066 17392787
AHR	EP300	◼ PHYSICAL_INTERACTION			0.88	0.88	HIPPIE	17392787 21988832 10999956
AHR	ARNT	◼ PHYSICAL_INTERACTION			979.0	0.97	STRING	36370105

Showing 1 to 10 of 1,235 entries