Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ESR1 ADA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11357058 18414489
E2F1 ADA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11888208 19541929
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
YY1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12039077 10030686
SP1 YY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22553354
TAF9 TAF6L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TP53 TFAP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18980971 16636674
TP53 TRRAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12138177 11779500
TP73 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19815500 0905867106
YY1 TP73 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17980704 18029729
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
KAT2A TADA2B â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ESR1 KAT2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16260778 31527615
TADA3 TP53 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
TAF10 TAF9B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17643375 24981860
KAT2A SGF29 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 26496610 18838386 26186194 31753913 21746879 28514442 20850016
TRRAP SGF29 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 20508642 24981860 26496610 20850016
SGF29 TAF12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 26186194 28514442 20850016
SGF29 TAF5L â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 26496610 26186194 28514442 20850016
SGF29 TAF9B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24981860
SGF29 TAF6L â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610 24981860
AA2AR ADA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 11125033
ADA POTEF â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TAF10 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 7923369
TAF6L KAT2A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 31753913 24981860
TAF10 TADA3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17643375 24981860 19114550 26186194 28514442
TAF6L TAF12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
PIAS2 TP53 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
TAF9B TRRAP â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
TADA3 RARA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20413580 12235159
TAF10 TAF5L â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
TAF12 TAF6L â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
GCR ADA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9154805 16189514
FANCM ADA â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
SUPT20H USP22 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
EXO1 ADA â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
ESR1 RARA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25604459 25303530 9717844
TAF6L TAF9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
TAF6L TRRAP â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
PIAS2 GCR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31182584 11117529
TERF2IP TINF2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ATXN7L3 SUPT7L â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
SP1 YY1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TADA2B TAF6L â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
DPP4 ADA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26209915 11772392 8568233 34709727
TRRAP E2F1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11418595 9708738 18542057
TADA3 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20413580 12034840 18089809 31527615
TAF12 TAF9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23292512
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ATXN7L3 TAF12 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SUPT7L TADA2B â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
TADA3 SGF29 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 32296183 24981860 26344197 22939629 26496610 26186194 25416956 16189514 20850016
GCR CREB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8449898 16713569 20203101 7621901 16189514
TRRAP ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11931763 16260778 12837248 12738788 31527615
RARA SP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10361124 19401466 16713569 18270252
ATXN7L3 TAF9B â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ATXN7L3 TAF5L â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
TAF10 TAF6L â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
SGF29 TADA3 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
YY1 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9199306 7494244 12296377
SP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10547281 8657141 10850422
E2F1 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10567569 8137237 18319725
TFAP2A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10497269 19458056 9850080
SP1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7559553
TP63 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
SP1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12039077 14962081 15249123
TFAP2A NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9015328 7794935
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
TP63 TADA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
TAF12 TAF10 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 14580349 24981860 19114550 7729427 12601814 23292512 9603525
TP73 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16413471 21436470 18026135
TP73 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11238924 19815500 10373484
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
KAT2A TAF5L â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
TAF6L TAF9B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
ATXN7L1 ATXN7L3 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
KAT2A SUPT20H â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
TADA2B TAF5L â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
SUPT20H TAF6L â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
SUPT3H USP22 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
TADA2B TAF9B â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
KAT2A TAF10 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
ATXN7L3 KAT2A â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
SUPT20H TAF12 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
TAF12 TRRAP â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ATXN7L3 TADA3 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
ATXN7L3 TRRAP â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
ATXN7L3 TAF10 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
TAF10 KAT2A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 17643375 24981860 19114550 12601814 17375202 31753913 10373431
TADA2B TAF12 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SUPT3H TAF6L â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
TRRAP USP22 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
TADA3 TAF5L â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ATXN7L3 USP22 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
TADA2B TRRAP â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
ATXN7L3 SUPT3H â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
SUPT20H SUPT3H â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
TADA3 TAF9B â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
KAT2A TADA3 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
KAT2A USP22 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
TAF5L TAF9B â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SUPT20H TAF10 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
SUPT3H TAF12 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
TADA2B TAF10 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
TADA3 TAF6L â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ATXN7L3 TADA2B â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
KAT2A SUPT3H â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
SUPT3H TAF5L â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
ATXN7L3 SUPT20H â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
KAT2A TRRAP â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SUPT20H TADA2B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SUPT3H TADA2B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
TADA3 TRRAP â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SUPT20H TRRAP â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TADA3 TAF10 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TADA3 TAF12 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
TAF10 TRRAP â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
SUPT3H TRRAP â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
SUPT20H TADA3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
TADA2B TADA3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
SUPT3H TAF10 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
SUPT3H TADA3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
TAF10 TAF12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TP53 ADA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19861536 14647469 16410722
TP73 ADA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14647469 19861536
TP63 ADA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19861536 16410722
SP1 ADA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8127716 12760745 1881892
ADA ADORA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9247966 12150791 16713569 18680557
ESR1 ADORA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19935720 19376833 18414489
NR3C1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20203101 16713569 8449898 7621901
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
E2F1 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9418871 19376752 17173070
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
TP53 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21715977 20805247 8557038 11795482 17210690 22952705
SP1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9054613 12697671 10446910 18440323
E2F1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10567569 7929342 7565760 15867358 16299810 8137237
E2F1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22241525 8557038 15706352 21441950 12675512 23954287 12625370
E2F1 TP73 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12766778 11101847 11988839 14602923 18660752 19188449 18029729 18521084 15210709 11115495 17980704 19363520 12789260 21310950 22952705
E2F1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22480684 11739724 12625370
E2F1 KAT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 36292703 20972224
E2F1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15210709 11988839 17488475 11937641
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
ESR1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8300756 8912864 8732679 11038749 15831516 15870697 10076999 9626663 18414489
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
TADA3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12034840 20413580 18089809 16713569
ESR1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 17641689 15831516 9717844 9841885
MYB NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16263717 15044598 22516378
SP1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16740727 7585542 15831516 9626663
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
SP1 TINF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21731707 9399940
YY1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10787423 10634504 8816507 10505791 18391986
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11238924 18431400 21508668 9891077
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
EXO5 ADA â—¼   KO_UP_REGULATES ✅ + 1.05 1.05 PKG 28854368
DDB2 ADA â—¼   KO_UP_REGULATES ✅ + 1.21 1.21 PKG 28854368
TP53 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -3.51 3.5 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368