Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CXCL12 DPP4 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
CDX2 MEP1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22326557
CDX2 DPP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21284881 16480684
FAP NPPB â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
NPPB DPP4 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
DPP4 CXCL9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6491341 18275857
DPP4 CXCL9 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
DPP4 TUBGCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6491341 18275857
DPP4 CCL5 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
TGFB1 COL2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 10085302
CXCL10 DPP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6491341 18275857
CXCL10 DPP4 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
ADCYAP1 FAP â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
TAC1 FAP â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
VIP FAP â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
FAP PYY â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
FAP NPY â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
GHRH FAP â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
HNF1B ACE2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24100303 16297991
USF1 TAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7654175 20690045
DPP4 TAC1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
CCL11 DPP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6491341 18275857
DPP4 CCL11 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
CXCL2 DPP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6491341 18275857
DPP4 CXCL11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6491341 18275857
HNF1B DPP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16297991 16781669
CXCL11 DPP4 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
CCL22 DPP4 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
CXCL2 DPP4 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
DPP4 NPY â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
DPP4 PYY â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
DPP4 CCL5 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21314817 11390394 9516414
DPP4 CXCL9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21314817 11390394 18275857
DPP4 CCL11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21314817 11390394 18275857
DPP4 SDF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21314817 11390394 18275857
DPP4 CXL11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21314817 11390394 18275857
DPP4 CXL10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21314817 11390394 18275857
SLC3A1 SLC7A9 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
BCL10 IKBKB â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CARD11 BCL10 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 7228517 19444310
DPP4 CCL22 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11390394 21314817 9933589
DPP4 ADA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26209915 34709727 8568233 11772392
USF1 USF2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HNF1B HNF1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 2044952 35140242 33961781 10484768
MYC CXCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC COL4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10918582 18444242 11258956
MYC TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC ATP1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
IKBKB BCL10 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19909372 16301747 16356855
IKBKB CARD11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19909372 16301747 16356855
ADORA2A IL2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 17371980 17909080 18758473
USF2 USF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18817855 28514442 16943425 17846119 17353931 21653943 9053857 26496610 33961781 8576131 15014447 19303849
GCG DPP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15655705 16517403 21314817
HNF1A DPP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10733933 16781669 9931303
COL4A1 COL4A2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
ATP1A1 FXYD2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ACE2 SLC6A19 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ATP1A1 ATP1B1 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
MYC SLC1A5 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11274345 11283613 11283614 11704864 17055429 17558397 17873522 19033189 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
MYC TGFB1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8962093 10702306 12695333 1349016 9417120
HNF1A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CDX2 SLC15A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18575574 19549526 16616718
CDX2 GCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9933606 17901057 11773447 14765989 17263687 10506141 16574312
BCL10 CARD11 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
BCL10 CARD11 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
USF1 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18955796 21389977 14757763 16457817 15983197 16488890
USF2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14757763 15184388 15983197 16488890
USF2 USF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14669984 12857727 11075816 19416648
HNF1B HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15486044 1363228 16793932 15001636
HNF1B DPP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9931303 16781669