Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
WRN ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
RECQL4 ECHDC3 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
EXO1 ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
MUS81 ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
XRCC4 ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
ERCC6 ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MDC1 ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
PAXX ECHDC3 â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
EXO5 ECHDC3 â—¼   KO_UP_REGULATES ✅ + 1.03 1.03 PKG 28854368
RAD18 ECHDC3 â—¼   KO_UP_REGULATES ✅ + 1.09 1.09 PKG 28854368
NHEJ1 ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
DDB2 ECHDC3 â—¼   KO_UP_REGULATES ✅ + 1.66 1.66 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368