Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
IQGAP3 EPS15L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
IQGAP3 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IQGAP3 SPRED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN IQGAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IQGAP3 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CALM1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9813038 8918462
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYC FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN MYC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 RHOJ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DDB2 GSN â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
RAC1 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAC2 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOJ CDC42 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10967094 31871319
MYC ACTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29467282 11839798
CALM1 ESR1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
LRRK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
DDB2 IQGAP3 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
RAC1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21454543 31046837
ESR1 ACTB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20308691 19805454 21182205 21182203 31527615 20348541
RAC3 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21217774 16331275
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
POLB IQGAP3 â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
MYC POLB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC ACTG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
ESR1 GSN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
CDC42 PXN â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10934474 11248548 11340065 15001467 15003621 15020669 15169870 15882626 16329184 17517963 17785506 18719708 19741094 21178402 22126964 22821962 27248291 7761442 9831565
ACTB IQGAP3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9368021 17244649 8756646 21730051 9199170
ACTG1 IQGAP3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9368021 17244649 8756646 21730051 9199170
CALM1 IQGAP3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22944912 21299499 21730051 9199170
RHOC ACTB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21576392 15507212 22275430 16439214 23222643 24914801 22094460
ACTB CDC42 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24914801 15507212 16439214 22608513
CDC42 ACTG1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24914801 15507212 16439214 22608513
RAC1 ACTG1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 18391171 16262445 11231582 9600938 15040784 12743368
RHOC ACTG1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21576392 15507212 22275430 16439214 23222643 24914801 22094460
GSN ACTG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11733011 7849017 15526166
CALM1 CDC42 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22944912 21299499 21730051 9199170
CALM1 RAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22944912 21299499 21730051 9199170
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
RAD18 GSN â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
PAXX IQGAP3 â—¼   KO_DOWN_REGULATES ✅ - -1.13 1.12 PKG 28854368
RAD18 KIFAP3 â—¼   KO_DOWN_REGULATES ✅ - -1.29 1.28 PKG 28854368
RAD18 IQGAP3 â—¼   KO_DOWN_REGULATES ✅ - -1.63 1.62 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368