Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
LONP1 ECSIT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
LRRK2 FANCM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
POLB PHGDH â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
EXO1 GCAT â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
PAXX GCAT â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
ECSIT NDUFS6 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
SETX GCAT â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
FANCM GCAT â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
POLB GCAT â—¼   KO_DOWN_REGULATES ✅ - -1.06 1.05 PKG 28854368
DDB2 GCAT â—¼   KO_UP_REGULATES ✅ + 1.06 1.06 PKG 28854368
NHEJ1 GCAT â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368
SETX SETX â—¼   KO_DOWN_REGULATES ✅ - -8.56 8.55 PKG 28854368