NKX2-1
|
NRP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18786351
18786357
|
NRP1
|
KDR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218708
16763549
|
VEGFC
|
KDR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0914318107
20145116
|
HIF1A
|
FLT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16601206
15192019
|
L1CAM
|
PLXNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10520994
15121181
|
SIA8D
|
NRP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
LYZL1
|
NRP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
DEF5
|
NRP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SIA8C
|
NRP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TSN11
|
NRP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SIAE
|
NRP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
FAM5C
|
NRP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SIAE
|
NAAA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
NAAA
|
NRP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
AT1B3
|
NRP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
NXPH2
|
NRP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
TAZ
|
NRP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
FLT1
|
FLT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.83
|
STRING
|
36370105
|
HIF1A
|
VEGFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
FLT4
|
KDR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
NRP1
|
VEGFA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10409677
9712843
26804163
9529250
11986311
30236477
22897854
11333271
18325345
20363638
11886873
16423422
10498602
22318724
17222790
21939755
16763549
|
HIF1A
|
VEGFC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18630523
17219968
15713437
|
L1CAM
|
NRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16377081
10520994
15121181
|
NRP1
|
PLXNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10520994
15121181
|
NRP1
|
VEGFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
NRP2
|
VEGFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
FLT4
|
VEGFC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
KDR
|
VEGFC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
FLT1
|
VEGFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
FLT1
|
KDR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
KDR
|
VEGFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
KDR
|
NRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
VEGFC
|
NRP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
25752543
16621967
16816121
8612600
|
SEMA3C
|
NRP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9331348
10196546
16816121
29067024
|
VEGFD
|
NRP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16816121
9435229
|
VEGFA
|
NRP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10748121
11181169
26991001
|
SEMA3B
|
NRP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
25335892
10196546
16189514
|
SEMA3F
|
NRP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
25068647
9883722
16816121
29067024
15721238
20387901
|
VEGFA
|
FLT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
VEGFA
|
FLT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15501236
15520864
15573129
16002046
16076871
16572188
17086423
19414323
21372296
22064427
22461508
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
VEGFA
|
KDR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
58.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19414323
19449109
19454690
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
VEGFA
|
KDR
|
â—¼ PROTEIN_INTERACTION
|
|
|
58.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19414323
19449109
19454690
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
VEGFA
|
FLT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15501236
15520864
15573129
16002046
16076871
16572188
17086423
19414323
21372296
22064427
22461508
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
VEGFA
|
FLT4
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
HIF1A
|
VEGFA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10804084
16110315
16127144
17533374
20427344
20535745
20855962
21051947
21372296
21765015
22006996
22461508
22850421
22988108
23390297
24006507
25043024
25103413
25732824
|
VEGFA
|
KDR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
58.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19414323
19449109
19454690
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
LMO2
|
VEGFA
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
17.0
|
1.0
|
ACSN
|
10048576
11528470
13130303
16556862
16716598
19208835
19839049
20589835
20731704
21081489
21224848
22349261
22439866
225147423
7768934
9278421
9811054
|
HIF1A
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
186.0
|
1.0
|
Omnipath
|
20303950
17085645
22609851
12697836
17557905
15140752
17431122
17486380
11866451
20453883
8756616
18027712
10702253
11678207
19046997
19491109
20127031
20307196
15315159
11359907
18233956
12032158
19502554
9178256
15956714
23060442
11350893
15930297
15207747
19074414
20660740
20489156
17089387
15735682
16506055
9746763
21793044
20436213
22789427
21814878
17053163
18835464
18072084
15983061
11749701
20875806
18432192
18471962
15039660
16750526
17322369
16052307
12433987
21447827
16682453
16971129
21258402
20027628
12542982
17272396
20574527
14712484
16865543
17916562
19664474
23354733
18060642
12570801
9235919
22903062
18563715
12154035
12612059
20599538
18572865
21187066
10837481
16596228
12963476
19828020
15169887
15156561
20232316
16969516
15111179
15342781
15475194
9398602
11001829
11191064
10882714
8387214
15191799
12820439
17413038
19111391
16854277
12509854
23404377
16900513
24347168
18021292
17947829
22771629
18295594
15774498
12205045
17498666
11007955
14699103
21145972
16618748
18322419
16540671
20724477
16778202
9393757
11549290
17065555
15315937
18024476
21343542
15705785
10987301
22306343
23086815
16774940
19420388
15050899
19759417
18289162
10415537
15277220
16818499
16982770
24464787
19238077
23028984
11056102
15838297
16301840
18578647
18702304
19020709
19564336
17461470
16515634
20043814
15806152
19336759
22750006
23185615
17470361
15746177
17889387
18339855
15890092
15663958
17704802
10477681
12052835
15382039
11707426
12855680
12023962
20432243
10611972
19819950
9359410
10640274
12393646
16311927
21435239
16357173
21731766
16543242
17481912
20449875
14602779
17167225
11486006
18294451
22076197
17999410
|
HIF1A
|
VEGFA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
7768934
11528470
9278421
17987801
16716598
12080085
10403805
16887934
7539918
1823643
12829734
13130303
15451019
9746763
8943284
15369676
9159130
11901189
22952674
11566883
|
VEGFA
|
FLT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
15637071
9393862
8356051
10543948
21939755
8621427
16633338
21441409
35874709
8631822
14704231
17051153
20660291
26285753
22348123
|
VEGFA
|
KDR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
22897854
15637071
1417831
23374253
12716911
18325345
16763549
31023826
8356051
16901919
24023956
17658244
20145116
8621427
11333271
16423422
22174934
16633338
11181169
27005951
9556609
8631822
17318185
12189247
31932617
23583373
20660291
19818105
24966171
21596751
|
VEGFA
|
NRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
9529250
17222790
17145710
22897854
15637071
18325345
16763549
20363638
21653826
21939755
11333271
16423422
11181169
9712843
11986311
10409677
22318724
10498602
|
VEGFD
|
KDR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
11004490
12881528
9435229
11387210
7824266
8617204
9207067
1417831
|
KDR
|
FLT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
KDR
|
FLT4
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
NRP1
|
KDR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17145710
17222790
11333271
16763549
11948691
19857463
26037503
|
VEGFC
|
KDR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
20145116
8612600
16633338
11332691
11181169
9435229
|
VEGFD
|
KDR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16835467
16633338
9435229
|
KDR
|
NRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17145710
17222790
11333271
16763549
11948691
19857463
26037503
|
HIF1A
|
FLT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7539918
1823643
12829734
9159130
13130303
9746763
12080085
11566883
10403805
8943284
15451019
11528470
9278421
16887934
9295307
|
VEGFD
|
FLT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
12881528
11532940
9435229
8617204
8700872
|
VEGFC
|
FLT4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
16530705
24798152
12881528
16336962
8700872
16633338
11532940
9435229
|
VEGFD
|
FLT4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11279005
16336962
16633338
11532940
21148085
9435229
|
SEMA3B
|
NRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
25335892
10196546
16189514
10196540
|