Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NCOR1 DACH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19351840 17182846
ZC3HAV1 DCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1101676108 21876179
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
ESR1 TRPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23031797 18414489
ESR1 LCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 21741997
EXOSC4 EXOSC10 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 7993626 20531386
PARN GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20932473
RNF40 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NCBP1 PARN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7898576 20379136
PARN ZC3HAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1101676108 21876179
UPF3B UPF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12718880 5216341
XRN1 ZC3HAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1101676108 21876179
NXF1 XRN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22658674 29395067
CI041 PARN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
ESR1 BCOR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 26487511
ESR1 PARN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
NXF1 RBM5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22658674 29395067
TULP3 PARN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DCAF13 EXOSC2 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
BARD1 MDC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12611903 29656893
BYST PARN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
H11 RRP12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
H11 PARN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TEAD4 PARN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DCP2 UPF1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ESR1 RRP12 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 21182205
NCBP1 RNF40 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
NCOR2 NCOR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10944117 11013263 16033423
RRP12 TSR1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
UPF2 UPF3A â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CSTF2 CSTF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10669729 26344197
NCOR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9171229 20392877 12738788 14715875 23403292 9702189
ESR1 TRPS1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23403292 31527615 26153859
BARD1 CSTF1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EXOSC10 MPHOSPH6 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EXOSC4 EXOSC2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 7993626 20531386
BYST RRP12 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
DACH1 NCOR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17182846 14525983
BARD1 CSTF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20379136 10477523 11257228
ESR1 BARD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17275994
NCOR1 DACH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 14525983
PARN DCP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15175153 16648466 11719186
DCP2 KHSRP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15175153 16648466 11719186
NCOR1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16469706 17400812 12145334 16713569 12738788 21182203 24051437
NCOR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17591692 23015261 15802375
KHSRP GADD45A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GADD45A JMJD1C â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PARN KHSRP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15175153 16648466 11719186
SIRT1 NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22395773 15175761
RPS15A TSR1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
BYSL ZRANB1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CSTF1 CSTF2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
UPF1 UPF3B â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
RPS6 TSR1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
XRN1 XRN2 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
BYSL DCAF13 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
DCAF13 UTP14A â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
BYST TSR1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 28514442 22863883 26186194
UPF2 UPF1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17469741 5219891
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
CSTF2 CSTF3 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CSTF1 CSTF3 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
BYSL RPS15A â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
EXOSC4 MPHOSPH6 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BYSL RPS6 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
EXOSC2 KHSRP â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMG7 UPF1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
BYSL TSR1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EXOSC10 EXOSC4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EXOSC10 EXOSC2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EXOSC2 MPHOSPH6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS15A RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
UPF1 UPF2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EXOSC2 EXOSC4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
UPF2 UPF3B â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TP53BP1 BARD1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
MAPKAPK2 AGO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 27701455 28683311 27117408 28757069 22936947 34117353 18476811 23603119 20626350 30154469
MAPKAPK2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 11175347 17389598 10679065 12356771 15733869 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 20626350 11909979 8688081
NCOR2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12738788 14715875 9171229 9702189 20392877
NCOR1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16469706 12738788 12145334 17400812 16713569 21182203
MAPKAPK2 PARN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20932473 19690332 16964243 18669648 21173571
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
NCOR1 NCOR2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
NCOR1 NCOR2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
SIRT1 NCOR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22395773 15175761 16713569
UPF3B UPF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 18066079 12723973 11163187 19417104
UPF2 UPF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 17145710 19478851 11544179 18256688 11073994 19150429 17469741 20371770 24778252 16452507 11163187 16086026 19503078 18066079 12723973 16488880 19556969 12417715 21145460 19417104 14527413
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368