Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAC3 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17625931
SPRED1 CD27 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDH1 EPCAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CGN YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MAP3K5 CIB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19805025 0812259106
CIB1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CIB1 SPRED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CIB1 ICAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CIB1 ITGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218469 16582881
CIB1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CIB1 PSEN2 â—¼   COLOCALIZATION 2.0 0.8 intact 5211550 10366599
CIB1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16061695
ITGA2B PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11476890 16919435
SPRED1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAG LSR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PRKDC YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PSEN2 PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
EPCAM LSR â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
LAD1 PKP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CDH1 PKP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
C6orf132 PKP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CASP2 YWHAG â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
ESRP1 GRHL2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PKP3 ST14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EPCAM PKP3 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
GALNT3 SPINT1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PKP3 SPINT1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
LAD1 ST14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EPCAM LAD1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ITGA5 ITGB3 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
CDH1 ESRP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
TMC7 CIB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ICAM1 PAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESRP1 SPINT1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EPCAM ESRP1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CDH1 EPCAM â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EPCAM ST14 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EPCAM SPINT1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
ITA2B CIB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10358085 24163826 9030514
CIB1 TERT â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15190070 20959453
CRTAP LEPRE1 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
SPINT1 ST14 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CDH1 SPINT1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
SPINT1 ST14 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PLK2 CIB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12651910 10523297
PLK3 CIB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11039900 10523297
ESRP1 ST14 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CDH1 ST14 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CIB1 M3K5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29644863 19805025
ITB3 CIB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24163826 9030514
PRKDC CIB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15190070 9372844
ITGB3 PTK2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
RAC3 CIB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11756406
ITA2B ITB3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7531639 19279667 1429573 10891446 30804189 11606749 14681455 15379538 15067009 11412103 9351872 17032655 19805198 25849143 30305279 22178926 18791937 15219201 14681217 10358085
ZEB1 GRHL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23943797 23814079
ITGA2 PTK2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11112697 25100717 9456329
CRTAP LEPRE1 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
PAK1 RAC3 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
NCK2 PAK1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
ITGA2B ITGB3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
PRKDC CASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19203584 28943433
ZEB1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 17997862 16424029 17615296 23890107 23160379 19435871 18411277 23667256 20139075 12508111 12714599 23518002 20207041 16862183 22249256 18321996 18805502 19706487 19839049 22147512 23743934 15674322 19921427 16804902 20332115 10949939 21771732 18487993 17655524 15311212 12161443 21593765
ZEB1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 15169839 9389648 17615296 22796940 19839049 20818389 21224848 20519943 21685935 12508111 11309385 11074002 225147423 19597490 12743038 14673164
PSEN1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10635315 11226248 16126725 11953314
CIB1 ITGA2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10358085 11756406 9030514
ITGA5 PTK2 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGA5 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10545505 7657702 9003039 11927607 19339212 19487819 19161977 16919435 7529872
ITGB3 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9169439 8649427 10545505 7657702 8636223 10022831 19339212 11927607 11940607 19161977 10592173 16919435 7529872 11553709 8755653 7512751
KAT5 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16603769 16904321
PAK1 NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 10026169 25416956 10592173 31515488 11557983 32296183 16713569
NCK2 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 10592173 11950595 16713569
NCK2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 10026169 25416956 10592173 31515488 11557983 32296183 16713569
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368