Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
AARD KRT24 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
BFSP2 KRT24 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
KRT20 KRT24 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
KRT24 TCHP â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
CUL4A DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
KRT24 KRT5 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
CUL3 CUL5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22709582 21145461
KRT24 KRT3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
KRT24 TXLNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
KRT3 KRT5 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
KRT24 KRT79 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
KRT24 SGF29 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
KRT24 KRT6C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
KRT24 KRT75 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
KRT1 KRT24 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
COPS6 CUL1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
NEDD8 CUL4B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 10597293 18274552 21145461 16503656 23201271 31973889 16620772
CUL4A CUL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17079684 32235678 21145461
KRT20 KRT3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
KRT24 KRT4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT20 TXLNA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT24 SNAPIN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
C1ORF216 KRT75 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
C1ORF216 KRT24 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
KRT75 TCHP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT75 TXLNA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CUL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
NEDD8 CUL5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18805092 24654937 33961781 18274552 10597293 21119685 21145461 23201271 24076655 18247557 28522566 22405651 31253590 28514442 20847044
KRT3 KRT75 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
KRT24 KRT71 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
COPS5 CUL4A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
KRT20 KRT75 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
COPS6 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
NEDD8 CUL2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 23401859 24654937 18274552 10597293 10318914 21145461 31444342 18826954 16503656 23201271 18247557 19617556 18173839 17132228 10585493 16620772
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21765416 16177058 18723677 18627766 17438373 32726803 24654937 11027288 18274552 10772955 16503656 24076655 18247557 22405651 17318178 10713156 19713960 10318914 21102408 23267066 23201271 22959436 17206147 16620772 18805092 10597293 21119685 21145461 18826954 19245792 19617556 12565873 18264111 24949976 22474075
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
CUL4A COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794