Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABI1 RASA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
ABI1 HCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
DCLRE1A DPP7 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
POLB DPP7 â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
HCK RASA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 7782336 16189514
FANCM MSH6 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CSK HCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11489946 16537894 10644735 11976726 14967142
MSH6 EXO1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20970388 17426132 14676842 16188885 16143102
GEN1 DPP7 â—¼   KO_DOWN_REGULATES ✅ - -1.11 1.1 PKG 28854368
DDB2 DPP7 â—¼   KO_UP_REGULATES ✅ + 1.3 1.3 PKG 28854368
MSH6 DPP7 â—¼   KO_UP_REGULATES ✅ + 1.35 1.35 PKG 28854368
NHEJ1 DPP7 â—¼   KO_DOWN_REGULATES ✅ - -1.45 1.44 PKG 28854368
FANCM DPP7 â—¼   KO_DOWN_REGULATES ✅ - -1.65 1.64 PKG 28854368
EXO1 DPP7 â—¼   KO_DOWN_REGULATES ✅ - -2.41 2.4 PKG 28854368
MSH6 MSH6 â—¼   KO_DOWN_REGULATES ✅ - -5.12 5.11 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368