Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H3-5 SMYD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
HSP90AA1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0908908106 19805354
HSP90AB1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21730179 1105160108
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
AR SMYD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 24174655
EZH2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 23239736
CDH1 EPCAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MKRN3 ENKD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
SMYD3 FLT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18784729
TP53 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
SMYD3 PBX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14667819 5216829
ZNF57 SMYD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
TRIT1 SMYD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SMYD3 TMA7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CDH1 ESRP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ESRP1 HELZ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SMYD3 KDM3B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
HIST3H3 KMT2E â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ESRP1 SPINT1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EPCAM ESRP1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SMYD3 HS90B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SMYD3 H90B3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SMYD3 HS905 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SMYD3 H90B4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RCAN3 SMYD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 EZH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
CDH1 EPCAM â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EPCAM SPINT1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CDH1 SPINT1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
HS905 HS90A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 22939629
SMYD3 HS90A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 15235609 26186194 28514442 16189514
H90B3 HS90A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 22939629
HS905 HS90B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 22939629
AR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HS90A ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18388150 23912458 17699868 9222609 15538384 21503962 22939624 20353944 16037132 19805454 27483141 23403292 11911945 12962497 9115298
AR CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18794357 20610535
AR MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20610535 20946682 17283128
TP53 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15383401 20332115 21478913
TP53 EPCAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19141643
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EZH2 EED â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
CDC37 HS90A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21871133 25036637 33961781 27353360 22729780 26496610 19875381 12930845 9685350 15647277 16335536 25486457 24462205 22504172 22939624 22315411 12176997 20159553 24292678 24189400 21360678 26804907 15001580 11413142 21745565 14718169 16611982
CDC37 HS90B â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28215707 25036637 33961781 26496610 11036079 22939624 23428871 27339980 24189400 25486457
HS90A HS90B â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 31536960 25036637 33961781 26344197 26496610 20353823 19875381 22863883 21360678
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EED EZH2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
HSP90AA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1525041 19805354 20048054 15861399 17974989 26342197 17353003 26196320 16713569 27903893 1540595 21157430 19706771
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
EZH2 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18377425 22130667 21685935 21770894
ESR1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12726856 14500345 17893710 19383788 19593637 20101232
EZH2 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 15169839 17615296 22796940 20818389 21685935 20519943 12508111 11309385 17018611 22514743 19597490 20574448 14673164
MET CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17496910 17336101 22558232 16909210 12040186 19568798 14585353
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
TP53 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16432214 20080630 17242190 20422012
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
TP53 NFYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 16959611 11096075 15831478