Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MYC AIMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
ATF2 RHOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11160903 21565167
CASP2 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 11399776
CASP8 CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18669646 0712034105
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP6 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 STK4 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 9545236 11278283
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
CASP3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17899380
CASP3 PTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12004072
CASP9 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
GTF2F2 CDK9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17690249 22492511
GTF2F1 CDK9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17690249 22492511
CDK9 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
CDK9 NCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
DDX41 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PTBP1 DNTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PTBP2 ELAVL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPK ELAVL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PTBP1 ELAVL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RBFOX2 ELAVL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
ELAVL1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19884656
ELAVL1 DUSP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18490444
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
EP300 DUSP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20626350 18504304
GTF2H4 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9118947 10734072
HNRNPF HNRNPD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PTBP1 HNRNPD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PTBP2 HNRNPD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
QKI HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SNRPA HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
MATR3 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HNRNPK RBM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPK YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HNRNPK RBFOX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPK PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HNRNPK MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8349701
MAPK3 CASP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219611 17290218
MAPK3 DUSP1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 10617468 8216666
DUSP1 MAPK3 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 20347885 8288600
MAPK3 METTL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 33217317
MAPK3 PCBP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17475908
PTBP2 MATR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
MATR3 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
MDM2 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214648 11588219
HIF1A MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12606552 15385570
ARRB2 MDM2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5214648 11588219
MYC CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOTCH1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10644343 16847353
MYC DUSP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14519204
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
PTBP1 NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218180 16376875
NPM1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
NPM1 IL7R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SFPQ PTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15975576 5217783
YBX1 CUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218767 16797541
YBX1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HNRNPF YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HNRNPF RBFOX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SNRPA PTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GABARAPL2 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
QKI PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PCBP2 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PTBP1 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PCBP1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
NCBP2 NCBP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
GABARAP HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ARRB2 NOTCH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22162134 16284625
HIF1A NOTCH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18427106 0802047105
NOTCH1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18427106 0802047105
NOTCH1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17537801
HIF1A HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19071119 6802010
FGFR2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8008273 18332103
YWHAZ CAND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PRKACA MAP1LC3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20713600
DDX23 PTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PTBP2 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GABARAPL1 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CALCOCO2 PTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HSPA5 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11943137
HNRNPAB PTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPAB PTBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RBFOX2 U2AF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
U2AF2 QKI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
U2AF2 CPSF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219196 17024186
U2AF2 SRPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
U2AF1 SRPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RBFOX2 PTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
NAT2 PTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RBM10 PTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PTBP1 ZMYM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15975576 5217783
PTBP1 PCBP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PTBP1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PCF11 CLP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10357856 10371034
CASP1 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18667412
RBFOX2 QKI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
QKI PCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
QKI PTBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
CASP6 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
HMGA1 RBFOX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RBM10 U2AF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PTBP2 RBM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PTBP2 PCBP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
YWHAZ KHSRP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17177604 19198587
CDK7 GTF2F2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DHX16 SRRM1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
DDX23 SNRPA â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ITGA4 YWHAZ â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
SRPK2 RRP1B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 26167880 33961781
CFTR YWHAZ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
HNRNPD HNRNPF â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
EP300 ATF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10327051 24069158
HNRPK CASP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDK9 HNRPK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17643375 26209609
CDK9 HNRPU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17643375 26209609
CDK9 PCBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 17643375
CDK9 ROA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17643375 26209609
CRY1 HNRPU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23133559 25756610
CRY1 SFPQ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23133559 25756610
CRY1 PTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23133559 25756610
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
DDX41 DDX23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 25920683
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
MYC MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
CUL1 MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29884807 21145461
PCBP1 MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 16713569
MATR3 BTF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 33644029
MATR3 HNRPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29884807 26496610
MYC U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC PCBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC HNRPK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 30415952
MYC DIM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC PTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
VCAM1 NONO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ELAV1 NONO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 19322201
ELAV1 RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20926688 19322201
HNRPU RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20926688 26496610
RRP1B DDX23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20926688
ELAV1 SFPQ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 19322201
VCAM1 SFPQ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CPSF7 SFPQ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34133714 24981860
VCAM1 PCBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HNRPK PCBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 16713569
BMI1 NCBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
NCBP1 ROA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19262567 22446626
CUL1 HNRPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34333526 21145461
BMI1 NCBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 PTBP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 YBOX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 PTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
CAND1 HNRPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28611215 21145461
CDKL5 DHX16 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
HNRPU U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26641092
CPSF6 U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26641092
U2AF2 ROA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26641092
U2AF2 HNRPD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 26641092
U2AF2 ELAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 26641092
SRPK2 CPSF6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 23602568
ROA1 CPSF6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 22446626
VCAM1 CPSF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CPSF7 ROA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 22939629
VCAM1 PTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
DIM1 PTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 22863883
PTBP3 PTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34133714 22575643
HNRPU PTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22863883 22939629
PTBP1 ROA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22863883 22939629
PTBP1 ODPA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29128334 26344197
PTBP1 HCD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29128334 26344197
PTBP3 SRRM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 22575643
CASP5 CASP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 HNRPK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
DIM1 YBOX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 22863883
YBOX1 HNRPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25497084 22118625
YBOX1 PTBP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25497084 33961781
ELAV1 HNRPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 19322201
HNRPD HNRPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26318153
VCAM1 HNRPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HNRPU HNRPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33174841 26496610
HCD2 ODPA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 22496890
ODPA ELAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 29128334
VCAM1 ROA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ELAV1 ROA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 26344197
ELAV1 PCBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 19322201
PCBP3 PCBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34133714 33961781
ROA1 PCBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 25324306
VCAM1 PCBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 HNRPD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HNRPD ELAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 26318153
VCAM1 HNRPU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 ELAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 ROA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 DIM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HNRNPH1 HNRNPL â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
CASP3 MDM2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 9278461 24842904 9840926 21726810
SRPK2 CDK7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32707033 23602568
CDK9 ROA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23455922 17643375 26209609
CDK9 CUL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11689688 12861003
CRY1 CUL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25756610 34237211 17463251 33961781
MYC ERCC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33381997 17314511 29467282
MATR3 HNRPU â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26344197
MATR3 ROA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 PTBP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 ELAV1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29395067 29884807
MYC NONO â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 17967896 29467282
MYC YBOX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 17967896 29467282
NONO U2AF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21566083 26641092 26344197
SFPQ U2AF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21566083 22939629 26641092
SRPK2 PCBP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26167880 23602568
ELAV1 BMI1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24457600 19322201 34316702
HDAC6 CFTR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31501480 22069321 14675537
HNRPK HNRPU â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33174841 26344197
DUSP1 MAPK3 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HNRNPF HNRNPH1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
MDM2 NPM1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
PARK2 PARK7 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CASP8 CUL3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MYC HIF1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 15071503 28205554
SRPK2 SNRPA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 23602568
HNRPD PCBP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9234743 26344197 10373504
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
QKI RBFOX2 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CASP9 CASP3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11242052 8900201 25241761 1067155 15941357 11230124 15507451 18723680 17437405
HNRNPAB HNRNPD â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
HNRPK MDM2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19249676 24583282 22825850 23092970
ROA1 NONO â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 25324306 22446626
CUL1 VCP â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
PTBP1 QKI â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34133714 22365833 16713569
HNRPK QKI â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32296183 16189514 29892012 25416956 16713569
HNRPU CDK7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17643375 10490622
MDM2 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20708156 24804778
RRP1B ROA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19710015 26186194
HNRPU SNRPA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 30021884
YBOX1 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16797541 21145461
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
YBOX1 PTBP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25497084 22863883
SOX2 ZMYM2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23667531 28794006
ELAVL1 HNRNPK â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CASP8 CASP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15254227 11832478 18669646 11437602 8962078
CASP6 CASP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 8900201 25241761 18723680
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
HNRPK MATR3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29511296 32296183 16189514 25416956 16713569 26496610 29884807
PTBP3 MATR3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29511296 26496610 29884807 33961781 22575643
YBOX1 MATR3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29511296 25497084 26344197
SNRPA U2AF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 22365833 21516116 25416956
U2AF2 HNRPK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22365833 26641092 22939629
CPSF6 CPSF7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26496610 33961781 24981860 22939629
HNRPD PTBP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22365833 26344197 22939629 22863883
ELAV1 PTBP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29395067 22365833 17967866
ROA1 PTBP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22446626 25324306 22863883 34079125 22939629 26344197
ELAV1 HNRPK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29395067 22365833 29931370
HNRPK HNRPD â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22365833 26496610 26318153
YBOX1 HNRPU â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22863883 22118625 22939629
DIM1 HNRPU â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27684187 22863883 26496610
ELAV1 PTBP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29395067 22365833 19322201
ELAV1 PTBP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29395067 22575643 19322201
ELAV1 ROA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22446626 25324306 29931370 26496610 34079125 29395067 19322201
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SNRPA U2AF2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CPSF6 CPSF7 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AIMP2 PARK2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HIF1A MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CASP3 MDM2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK9 MYC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HNRNPD PTBP1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PTBP1 SNRPA â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HNRNPL PTBP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MYC CDK9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12944920 19818711 26687678 11673469 17700062 30415952
EP300 RORA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9862959 16713569
ROA1 MATR3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29511296 22446626 25324306 26496610 29884807 34079125
PCBP1 PTBP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27684187 16713569 26344197
PCBP1 PCBP2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27684187 23640898 16713569 26344197
CASP8 CUL3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19427028 23142077 25551360 28574503
IKZF1 IKZF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 9155026 26823144 33961781 10204490
PCF11 CLP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
ELAV1 QKI â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29395067 19322201
HNRPD YBOX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12674497 26496610
CASP10 CASP8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HNRNPA1 HNRNPL â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ARRB2 MDM2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NUDT21 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HNRPU EP300 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11909954 33742100
ROA1 SFPQ â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 20932480 22446626 26344197
SFPQ SNRPA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21566083 34133714 9848648 17507659
HNRPL PTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10772858 16713569 9563502 22939629 26344197
PCBP2 PTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 10772858 16713569
PTBP1 HNRPK â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 10772858 26344197
MED10 MED29 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
PCBP2 HNRPK â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 10772858 16713569
YBOX1 ROA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25497084 22863883 22118625 22939629
ROA1 HNRPD â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22446626 25324306 26496610 26318153 34079125 22939629
HNRPU ROA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25324306 26496610 22863883 34079125 22939629
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
NONO SFPQ â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MED10 MED19 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED19 MED29 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MATR3 AIMP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ATF2 DUSP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17681939 20702711 24126911
MYC CASP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
CDK7 ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 8692841 17643375 15220921 8521393 33453189 33961781 10082552 9130708 23602568 28977422 32707033 29568061 26340423
CDK9 RCHY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23603988
COPS5 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11707426 18926707
COPS5 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18926707 17879958
HDAC6 ELAVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18644987
EP300 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15154850 20234175 16713569 11070080 9809062 28196907 15013777
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
HIF1A MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12606552 10640274 25447306 15880652 19696166 25535359 17234751 15385570
MDM2 ARRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17984062 15878855 32450252 26545496 12488444 11588219 21988832 21466165 33649538 21389118 18544533 21081496 32828283 12538596
MYC CLP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC PDHA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PTBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20010808
MYC YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12080043 18414489
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC SMARCAD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
NOTCH1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
SFPQ NONO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17452459 18042045 11259580 21988832 25959826 30445466 12403470 31815296 30725116 34017080 33961781 24981860 17507659 30021884 22939629 26344197
SFPQ PTBP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 8449401 17507659 11514619 10653975 15975576
U2AF2 SNRPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25416956 22365833
YWHAZ GABARAPL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKACA FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20658524
IKZF1 NOTCH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21093322 18941217 18852286
NOTCH1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18722525 23331499 16256737
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
LRRK2 DNM1L â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22228096 22639965 24282027 29541021 23813973
PRKACA LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21390248 24351927
HIF1A RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15270719 14742449
IKZF1 IKZF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17383641
CASP10 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8755496 8962078
U2AF2 SRPK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16189514 16713569 33961781 9472028 23602568 32707033
U2AF1 SRPK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25416956 22365833 34133714 33961781 23602568
SRPK2 SRRM1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 26167880 33961781 23602568
MED10 MED29 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 24882805 14576168 33961781 24981860 26344197
MED10 MED19 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 12584197 15989967 24882805 14576168 33961781 24981860 21729782 26186194
CASP4 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12843244 9491891 9039262
MED29 MED19 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 24882805 14576168 33961781 24981860 21729782 26186194 26344197
HNRPL HNRPK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10772858 16713569 33174841 22939629 26344197
ROA1 HNRPK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22446626 25324306 17643375 26496610 34079125 22939629
ROA1 HNRPL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22446626 25324306 17643375 26496610 34079125 22939629
HNRPL ROA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28611215 22939629 23976881 10441480
ROA1 ROA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25324306 17643375 26496610 22863883 24981860 30021884 34079125 22939629 26344197
HNRPD ROA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 26318153 22939629 30021884 26344197
HNRPU HNRPD â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26318153 22365833 26496610 30021884
ERCC3 GTF2F1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2F2 GTF2H4 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
LRRK2 YWHAZ â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HNRNPA1 HNRNPH1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
SRPK2 U2AF2 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
PCBP1 SNRPA â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
HNRPK YBOX1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 10809782 22939629 16713569
GTF2F1 GTF2H4 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
HNRPK FYN â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 16189514 16713569 7516469 9185665 31413325
CDK7 GTF2H4 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
DHX16 RNF113A â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
U2AF2 U2AF1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 8153045 21516116
CLP1 PCF11 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
HIF1A EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17382325 5219810
NCBP2 NCBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
ERCC3 GTF2F2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CPSF7 NUDT21 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
HIF1A EP300 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15280364 19589782 16543236 11823643 22807441 19666581 16189267 18047470 15342390 12042299 19680224 22735262 23448368 26135796 23618863 14691445 19696166 11959990 27320910 16847340 24821806 22789427 17906695 8917528 20620956 20000859 15261140 16081065 12778114 22219185 15154850 25192544 22075993 19071119 22908229 19940151 21187066 24421387 23880760 11940656 23966271 26826385 26944191 12588875 23746844 11063749 27808477 19074848 20603618 15155277 18268343 20829524 21148070 12914934 17502379 22684029 17382325 26751287
NCBP2 NCBP1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 23665581 9933612 26382858 31467278 11545740 22365833 26496610 29395067 12374755 26264872 7478990 19668212 22939629 29997244 32814053 29101316 24981860 31448526 17190602 12434151 26344197
CPSF6 NUDT21 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
U2AF2 U2AF1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 32296183 16189514 25416956 26641092 16713569 22939629 21988832 26264872 22365833 21460037 33961781 8647433 21516116 1388271 11551507 26344197
HNRPL PCBP2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16713569 10772858 8871564 21623344
METTL14 METTL3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
NCBP1 NCBP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2F1 GTF2F2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MAPK3 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10777545 12110590 20068231 15304344 15192015 19647037
PRKACA ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1661585 15105425 92095966
CASP3 CASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9261102 9922454
CASP2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15262979 16193064
CASP10 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11717445 8755496 9765224
CASP8 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 15755874 17179148 9501089 9950028 18669646 23308069 10988287 18458084 16964285 9885230 9765224 11437602 15014070 21295084 8962078 9208847
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
CASP3 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25241761 9278461 21726810 24842904 9840926
CASP3 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11278782 11278283 11517310 9545236
CASP3 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25241761 17899380 8900201 9922454 18723680
CASP7 CASP9 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 16916640 9922454 11752425 11701129 12824163
PRKACA CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 29352269 15703181
MAPK3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 15547943 20080742 29416675 12040186 15173823 12697810 11940578 19081073 19586613 16227978 12738796 16039586 17466630 17255949 18669648 15187187 19016842 19541618 19091303 19565474 17052211 18039929 18775330 10601235 12792650 11431469
CASP9 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14686614 9651578 16521476 12097334
CASP9 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17899380 9922454 16352606 9598997 9651578
CDK7 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
PRKACA CUL5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19917606 21635549 10898738 12917106
IKZF1 DNTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8887642 11459831 7935426 1922043 18223295
ELAVL1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18519672 19574298
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
GTF2F2 ERCC3 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2F1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
PRKACA HNRNPD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19651622 11903055 12819195 17287340
MAPK3 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11259409 16564677 11231586
MDM2 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19249676 16360036 23092970
HNRNPK MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19249676 16360036 23092970
FGFR2 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
DUSP1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 23331499 12676937 7761091 10617468 25241761 8221888 7535768 20347885 7939666 20858750 11278799 9430728 9922370 14695202
MAPK3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18463697 9155018 21071413 32482868 18988627 15210690
MAPK3 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24089523
MAPK3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10551817 18519666 24099156
MAPK3 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 24342355 17290218 26036637 29233910 24484936 20937773
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
MDM2 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 15880652 25535359 12606552 25447306 17234751 19696166 10640274
GTF2F1 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
NCBP2 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
GTF2F2 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
NCBP1 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
MYC CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15367674 12695333
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC HNRNPA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12747840 20010808 12695333
MYC IGF2BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21779431 18414489 21252116
SFPQ NONO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17452459 21988832 17145710 17507659 12403470 11259580 30021884 10858305 18042045 20421735 25959826
NPM1 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22955283 31434245 16009132 12748172
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
PTBP1 NCBP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
NCBP1 METTL14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
NUDT21 CPSF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 16189514 25416956
ITGA4 FYN â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
IL7R FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7515933 16713569
NOTCH1 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11585921 15546612 11461910 18094723
PRKACA ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21224395 20166139 18578522 23979717 31562188 18583710 18707149 17603879 19401330 12837751 11533025
VCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22623428 19738201 11751331
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
PDHA1 DLD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
CASP8 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18073771 9545235 10872455 18329793 9727491 9463409
CASP8 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18329793 12232792 9727491
CASP8 CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 22864571 17159907 17145710 12887920 11832478 11717445 21737330 15280356 12198154 3031469 15659383 170210 8962078 22421964
HMGA1 HMGA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
PRKACA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 28003367 23060444 25867080 21455600 30600261 1716180 28242698 19328185 32102849 92316961 19095655 14602047 7530719 10581361 11053017 9385646 25330774 15657296 1377674
PRKACA HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22865920 20716686
PRKACA PTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12851456 18669648
PRKACA NEDD4L â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 30453017 15328345 15677482
PRKACA YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 29109150 11956222 12861023 16376338 19451227
HNRNPA1 NCBP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
HNRNPA1 GTF2F2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
HNRNPA1 PTBP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
PTBP1 NCBP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
NCBP2 METTL14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
GTF2F2 PTBP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
GTF2F2 METTL14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
GTF2F2 GTF2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7854423 11278533 31467278 11183778 8441635 16189514 8662660 7827505
PTBP1 GTF2F1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
GTF2F1 METTL14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
CASP1 CASP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541