Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CASP1 NLRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0802726105 18511561
IL1B CASP1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0812690106 19439663
CASP5 IL1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17039247
EIF3A EIF4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 17353931
CASP5 RHG44 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CASP5 CASP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CASP5 LACRT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CARD17 CASP1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
CASP1 GSDMD â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
EIF4G2 EIF4G3 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
PYCARD CASP1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 34589402
EIF4G1 EIF4G3 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
EIF3A EIF4G1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CASP4 GSDMD â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EIF4A1 EIF4G2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CASP1 IL18 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 1574116 9121587 8999548
CASP4 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12843244 9491891 9039262
CASP5 IL18 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9121587 17039247
EIF4G2 EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10394359 16467844 10944120
EIF4A1 EIF4E â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
EIF4A1 EIF4G3 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
EIF3A EIF4A1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
EIF4G1 EIF4A1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219000 16932749
EIF4E EIF4G3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CASP1 PYCARD â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
EIF4E EIF4G1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EIF4A1 EIF4G1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COP1 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11051551 11536016 11432859 15383541
COP1 CASP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
COP1 PYCARD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
COP1 NLRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
CARD17 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15383541 27043298 11051551 11536016 11432859
CARD17 CASP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
CARD17 PYCARD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
CARD17 NLRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
CARD18 NLRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
CARD18 CASP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
CARD18 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 15383541 27043298 11051551 11536016 11432859
CARD18 PYCARD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
CASP1 NLRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 21252346 12191486 15383541 17418785 15107016 11051551 11536016 11432859 18511561
CASP1 IL18 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22270365 17039247 15326478 9121587 9334240
CASP1 CASP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
CASP1 PYCARD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 24630722 25605870 12191486 15383541 11051551 11967258 11536016 24803432 21385879 26121674 11432859 12019269 16585594 19337385 14634131
CASP1 IL1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 1919001 7642516 7797510 17039247 28147281 8999548 19439663 9121587
NLRP1 CASP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17418785 12191486
EIF4G1 EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 8521827 22509910 17689282 23665581 22586265 16648488 16467844 9372926 16541103 15361857 16720573 9418880 16281055 18955708 12071973 21191102 26186194 10753870 15153109 10600798 7651417 20212144
PYCARD IL1B â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 19104081 20385749 23202296 26885855 27048821 27066895 27439607 27984721