Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
IL1B CASP1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0812690106 19439663
CASP5 IL1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17039247
IL1B CASP8 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 1574116 22267217
MFHAS1 GSDMD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
SYVN1 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
CASP5 CASP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CASP1 GSDMD â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
CAV1 CAV2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CASP4 GSDMD â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CAV1 PTRF â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
GSDMD ZBTB33 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
GSDMD KCTD6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CAV1 CAV2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
GSDMD MEOX2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CASP4 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12843244 9491891 9039262
CAV2 CAV1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9361015 31980649 18081315 12414992 24013648 10212252 16189514
MSH2 GSDMD â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
PMS1 GSDMD â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CASP1 CASP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
CASP1 IL1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 1919001 7642516 7797510 17039247 28147281 8999548 19439663 9121587
POLB EPHA1 â—¼   KO_UP_REGULATES ✅ + 1.15 1.15 PKG 28854368
H2AFY2 GSDMD â—¼   KO_DOWN_REGULATES ✅ - -1.17 1.16 PKG 28854368
TDG CAV1 â—¼   KO_UP_REGULATES ✅ + 1.37 1.37 PKG 28854368
POLB GSDMD â—¼   KO_DOWN_REGULATES ✅ - -1.39 1.38 PKG 28854368
TDG GSDMD â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.6 PKG 28854368
H2AFY2 H2AFY2 â—¼   KO_DOWN_REGULATES ✅ - -3.83 3.82 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
MSH2 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -6.48 6.47 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368
PMS1 PMS1 â—¼   KO_DOWN_REGULATES ✅ - -7.89 7.88 PKG 28854368