Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CD2 LCK â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6548030 9677430
EEF1D CD48 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PLCG1 LCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
LCP2 PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10469124 16189514
PRAP1 CD48 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CBL LCP2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
LCK CD48 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 8104794 16189514 12007789
CD244 CD48 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
LCK LCP2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10556826 16354835 8702662 21725281
LCP2 CBL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9716598 10204582 19635790 10477741
LAT PLCG1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
LCP2 PLCG1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CBL PLCG1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CBL LCK â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CD244 SH2D1A â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CD2 LCK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19398758 19494291 26794910
LCK LAT â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12186560 14523017 16938345 12359715
LAT PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27221712 10469124 16189514
LCK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7682059 17570479 1500851
CD2 CD48 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 12356317 16189514
CD2 LCK â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 9677430 16189514 8551220
PLCG1 CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9234717 12941616 25241761 16467851 12061819 9712732 16713569 16503409 17372230 12803489
CD48 CBL â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
SH2D1A CBL â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
LCK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 9525940 10829062 10799548 10934191 7721825 16107303 12604776 9890970 17570479 11904433 9178909 10092522 11997497 12522270 8621719 9102067 11239464 11994282 11741956
CBL PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 7517397 9712732 12941616 25241761 12061819 23109003 9234717 16503409 11709089 16713569 17372230 16467851 12803489
CD48 CD2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 10359122 15998796 16081768 19398758 19494291 26794910
CD48 CD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10359122 15998796 16081768 19398758 19494291 26794910
CD2 LAT â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10359122 15998796 16081768 19398758 19494291 26794910
CD48 CD244 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 10359122 15998796 16081768 26794910
CD48 CD244 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26697006 9834056 26794910 16002700 11163399 15870174 18296487 15153464
CD244 SH2D1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19150402 15169881 16983070 24642916 23346089 11489943 15187115 26221972 10358138
CD48 LCP2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
KIR2DL1 CD48 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
HLA-C CD48 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
KIR2DL4 CD48 â—¼   DOWN_REGULATES ✅ - 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
KLRB1 CD48 â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 16339513 18159636 20435894 22378844 24227772 8478617 9603467
FCER1G CD48 â—¼   DOWN_REGULATES ✅ - 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
CD48 LAT â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
CLEC2D CD48 â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 16339513 18159636 20435894 22378844 24227772 8478617 9603467
CD48 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
CD48 SH2D1A â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
HLA-G CD48 â—¼   DOWN_REGULATES ✅ - 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
CD48 PLCG2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
CD48 SH2D1A â—¼   SHARES_COMPLEX 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
KLRB1 CLEC2D â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 16339513 18159636 20435894 22378844 24227772 8478617 9603467
CLEC2D SH2D1A â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 16339513 18159636 20435894 22378844 24227772 8478617 9603467
CLEC2D FCER1G â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 16339513 18159636 20435894 22378844 24227772 8478617 9603467
FCER1G HLA-G â—¼   PHYSICAL_INTERACTION 29.0 1.0 ACSN 10562324 10925299 11353765 11385609 11438547 11489965 11513144 11875494 11994457 12055234 12731048 12811837 15081523 15778339 16287995 16713974 17100877 20435894 20814939 21059766 22267813 23414611 23508573 24378531 8478617 9603467 9625766 9738502 9751747
FCER1G KIR2DL4 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
FCER1G KIR2DL4 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
FCER1G HLA-G â—¼   SHARES_COMPLEX 29.0 1.0 ACSN 10562324 10925299 11353765 11385609 11438547 11489965 11513144 11875494 11994457 12055234 12731048 12811837 15081523 15778339 16287995 16713974 17100877 20435894 20814939 21059766 22267813 23414611 23508573 24378531 8478617 9603467 9625766 9738502 9751747
LCK FCER1G â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 8478617 8986721 9438848 9738502 9751747
KLRB1 FCER1G â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 16339513 18159636 20435894 22378844 24227772 8478617 9603467
FCER1G KIR2DL4 â—¼   DOWN_REGULATES ✅ - 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
FCER1G SH2D1A â—¼   DOWN_REGULATES ✅ - 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
FCER1G HLA-G â—¼   DOWN_REGULATES ✅ - 29.0 1.0 ACSN 10562324 10925299 11353765 11385609 11438547 11489965 11513144 11875494 11994457 12055234 12731048 12811837 15081523 15778339 16287995 16713974 17100877 20435894 20814939 21059766 22267813 23414611 23508573 24378531 8478617 9603467 9625766 9738502 9751747
HLA-C KIR2DL1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
HLA-C SH2D1A â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
HLA-C KIR2DL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 58.0 1.0 Omnipath 15580655 11163076 10429675 28484462 9686591 9768753 9378975 11323700 12454284 16141329 28546555 11955593 15607823 18624290 11009104 12794140 31519864 19858347 10820396
HLA-G KIR2DL4 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
HLA-G KIR2DL4 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
HLA-G SH2D1A â—¼   DOWN_REGULATES ✅ - 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
HLA-G KIR2DL4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11955593 15580655 26973020 17056715 10190900 16487070
KIR2DL1 SH2D1A â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
KIR2DL4 SH2D1A â—¼   DOWN_REGULATES ✅ - 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
KLRB1 SH2D1A â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 16339513 18159636 20435894 22378844 24227772 8478617 9603467
PLCG1 LAT â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
PLCG1 LAT â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
SH2D1A LAT â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
PLCG1 LAT â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
LAT LCP2 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
LAT PLCG2 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10072481 10086337 10567412 10781611 10811803 10982827 11169415 11447289 11777939 12175651 12640133 14764585 15567848 15574420 16102570 16329184 16582911 16887996 17496910 17673906 19449109 19494291 19909365 23620508 25137453 26552706 7523143 7890616 8551221 8649391 8976179 9489702 9535722
LCK LAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16938345 12359715 12186560 27700984
LAT PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 27221712 11368773 9489702 12941616 15286727 10811803 23109003 24642916 16938345 11709089 16713569 15219999 16467851 9729044
LCK PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 19901323 12181444 11606584 14656219 7682059 15144186 11507089 17570479 16497976 15184383
LCK LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 16354835 21725281 8702662 10648627 10556826
PLCG2 LCP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11390650 20484116 10811803 12471105
SH2D1A LCP2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
PLCG1 LCP2 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
LCP2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 12941616 9341187 23109003 21725281 15929943 11709089 16467851 11390650
SH2D1A PLCG1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
SH2D1A PLCG2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722