Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PTPN6 CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18173375 18759926
FYN CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7524477 6730342
CSK PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18173375 18759926
CSK PTPRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6672875 7507203
CSK PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 15574420 14665621
CD244 ARHGEF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16983070 0606624103
SH3BP2 CD244 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731716 16177062
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
PLCG2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PTPN6 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10660620 6671678
GRB2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PLCG1 PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
SH3BP2 PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731300 11390470
PTPN6 SH3BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16649996 6672211
GRB2 CSK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21706016 31980649
CD244 BIG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
IMMT CHCH6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27153535 17624330
CD244 CHCH6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MTX2 BINCA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD244 HEAT6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CD244 ST7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CD244 FYN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15169881 23346089
CD244 LTN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CD244 MTX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD244 MTX3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD244 RIMB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD244 RN213 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD244 PDXD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD244 BINCA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD244 CAND2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD244 POMT1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD244 POMT2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD244 MTOR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD244 MYADM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD244 IMMT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PTN11 FYN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11157475 16189514 16713569 10212213
SHIP1 CD244 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24642916 26221972
IMMT MTX2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CD244 CD48 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
SHIP1 PTN11 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9110989 11453982 11157475
CSK PTPRC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19167335 7507203
GRB2 INPP5D â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
PTN11 CD244 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24642916 10358138
MTX2 CHCH6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32877691 26496610
MTX2 MTX3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32877691
FYN PLCG2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12181444 8395016 15144186 7682059 16713569 16189514
LAT PLCG1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CD244 SH21B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24642916 23346089 11689425
CD244 SH2D1A â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CD244 SH2D1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11689425 23346089 24642916
FYN SH3BP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15345594
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
FYN LAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16938345
LAT GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10811803 23460737 7544353 9489702 12359715 12186560 16938345 16713569 16906159 8063801 11368773 16189514
INPPL1 INPP5D â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9108392 9099679 10570274
LAT PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27221712 10469124 16189514
PTPN6 SH3BP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16649996
GRB2 PTPN11 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
SHIP1 GRB2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 11453982 8723348 9108392 10900203 22267732 12149229
PLCG1 GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 21706016 7629168 10940929 16038803 9020117 16713569 9281317 7516467
FYN SH2D1A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
IMMT MTX2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
PTN11 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 8702859 33961781 12531430 34407391 10747947 9824671 12577067 9361008 9660791 19380743 7534299 8995399 16371368 10080542 21706016 20473329 7523381 8041791 9362449 10212213 8647120 28514442 16189514 9632781 31980649 9254654 8959326
SH21A FYN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12545174 12458214 16983070 16713569 25416956 10089404
SH21A CD244 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11477068 24642916 15169881 16983070 23346089 16920955 11489943 15841490 10358138 26221972
CSK FYN â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10790433 11181701 12485116 15713798 19290918 8011291 8986721
CSK FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 1985196 8262983 11489946 16537894 9647655 25720756 18691976 10366594 19369195 1533589 1699196 7524477 16713569 15713745 14967142
CSK PTPRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7507203 19167335
B2M PTPRC â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10358761 10559964 11154916 11509172 11717192 14508489 16181333 22076556 22790179 24457417 8642276
CD48 CD244 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 10359122 15998796 16081768 26794910
CD48 CD244 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26697006 9834056 26794910 16002700 11163399 15870174 18296487 15153464
CD244 SH2D1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19150402 15169881 16983070 24642916 23346089 11489943 15187115 26221972 10358138
CD48 LAT â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
CD48 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
CD48 SH2D1A â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
CD48 PLCG2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
CD48 SH2D1A â—¼   SHARES_COMPLEX 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
FYN SH2D1B â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10591186 10648627 11062502 12218089 12731048 15536084 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
FYN PTPN11 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10591186 10648627 12218089 12731048 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
FYN PTPRC â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10591186 10648627 12218089 12414720 12731048 19290918 19909365 20814939 21378271 22683124 22863785 23620508 23886063 24440149 25312647 27192565 9738502
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SH2D1A FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10089404 16983070 16713569 12545174
PTPRC FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 1985196 8980254 11909961 1464315 1533589 9535845 16713569 9368621 12589038
FYN PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10212213 11157475 16713569
FYN PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19901323 8395016 12181444 11606584 14656219 7682059 15144186 11507089 16497976 16713569
FYN PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8395016 10586033 7682059 16713569
GRB2 LAT â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 PLCG1 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 PLCG1 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
PTPN11 GRB2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10358138 11447289 11572860 12138178 12707331 15240681 15699106 15713798 19833085 9751747
GRB2 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 LAT â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 PLCG2 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10072481 10086337 10567412 10781611 10811803 10982827 11169415 11447289 11777939 12175651 12640133 14764585 15567848 15574420 16102570 16329184 16582911 16887996 17496910 17673906 19449109 19494291 19909365 23620508 25137453 26552706 7523143 7890616 8551221 8649391 8976179 9489702 9535722
LAT GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 11368773 9489702 10811803 8063801 17043143 16938345 16713569 23150273 12186560 16906159
PTPN11 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 8702859 9361008 16371368 21706016 8041791 11085989 8978300 11432792 15882975 9362449 10212213 11684012 7523381 10592173 16189514 10747947 10973965 9632781 8959326 11602579 12577067 9254654 10080542 15010462 31585087 12531430 8995399 19380743 7522233 9804835 7534299 9824671 9660791
GRB2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9281317 15953601 7629168 9020117 16713569 10940929
GRB2 INPP5D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10660611 32323266 15456754 10748054 17043143 9108392 10900203 10068665 10891441 22267732 8723348
PLCG1 LAT â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
PLCG1 LAT â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
SH2D1A LAT â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
PLCG1 LAT â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
LAT PLCG2 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10072481 10086337 10567412 10781611 10811803 10982827 11169415 11447289 11777939 12175651 12640133 14764585 15567848 15574420 16102570 16329184 16582911 16887996 17496910 17673906 19449109 19494291 19909365 23620508 25137453 26552706 7523143 7890616 8551221 8649391 8976179 9489702 9535722
LAT PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 27221712 11368773 9489702 12941616 15286727 10811803 23109003 24642916 16938345 11709089 16713569 15219999 16467851 9729044
SH2D1A PLCG1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
SH2D1B PLCG1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10426994 11907067 15536084 16339536 16713974 17599905 19151721 24687958 25312647 7890616 9535722
SH2D1A PLCG2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
SH2D1B PLCG2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10426994 11907067 15536084 16339536 16713974 17599905 19151721 24687958 25312647 7890616 9535722
PTPN11 PTPN6 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283
PTPN11 PTPN6 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283
PTPRC SH2D1B â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12414720 19290918 23620508 23886063 25312647