KRAS
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16483930
29311131
|
HIF1A
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17558861
19211554
|
BCL2L1
|
MAPK8
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
15733859
5217553
|
CHCHD6
|
CHCHD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
TP53
|
CSNK2A2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12393879
11239457
|
CSNK2A2
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10938077
|
E2F1
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20800677
|
E2F1
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11799067
|
E2F1
|
ULK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18408756
|
E2F1
|
MAP1LC3A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18408756
|
FOXO3
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18268343
0706790105
|
FOXO3
|
PINK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19276113
|
FOXO3
|
BNIP3L
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12351634
|
FOXO3
|
CITED2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17353275
18158893
|
YWHAQ
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10102273
|
FOXO3
|
BNIP3L
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16166289
|
ESR1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
3677090
|
OPA1
|
OMA1
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20038677
19001017
|
SMURF2
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18157088
6492033
|
SQSTM1
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
MAP1LC3A
|
SQSTM1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
TP53
|
PPP1CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
TP53
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11350971
10984493
|
TP53
|
PHB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7717349
20134482
|
TP53
|
CSNK2B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12393879
11239457
|
TP53
|
CSNK2A1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12393879
11239457
|
TP53
|
BNIP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21792176
11550088
|
TP53
|
BNIP3L
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15607964
|
TP53
|
MFN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22510407
20804729
|
TP53
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10766163
16713569
|
TP53
|
BNIP3L
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
ATF4
|
DISC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12812986
|
BCL2L13
|
GABARAPL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
GABARAPL2
|
CALCOCO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
CSNK2A1
|
CSNK2B
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
TBC1D17
|
OPTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
RELA
|
OPTN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19340308
|
TBC1D15
|
GABARAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20562859
|
BECN1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RELA
|
BECN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19289499
19458474
|
RPS27A
|
PRKN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
26161729
24856362
|
UBB
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CALCOCO2
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
TRAF2
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TRAF2
|
MAPK9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
10490605
|
HRAS
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12695509
5216326
|
UBC
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7104155
19343052
|
JUN
|
MAPK8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
JUN
|
MAPK9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
JUN
|
MAPK10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
HIF1A
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15794924
19828020
|
RELA
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17310108
10646503
|
JUN
|
PRKN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20638938
21113145
|
MAPK9
|
JUN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19527717
7148309
|
JUN
|
MAPK10
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19527717
7148309
|
PRKN
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20418918
|
RELA
|
PINK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25108683
|
PINK1
|
MAP1LC3B
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
20153330
7557104
|
CSNK2A1
|
RELA
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5212888
10938077
|
HIF1A
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19934262
15780936
|
CSNK2A1
|
HIF1A
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
17382325
5219810
|
UBC
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6504434
17936276
|
RRAS
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SRC
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
UBC
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7104155
19343052
|
SP1
|
KRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8887648
19994725
|
SP1
|
BNIP3L
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16291751
|
TAX1BP1
|
TBC1D17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
YWHAQ
|
USP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
NBR1
|
USP8
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
FIS1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16874301
5218876
|
ZRANB1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
UBC
|
PHB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7717349
20134482
|
UBC
|
MARCHF5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16874301
5218876
|
UBC
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18636086
6804508
|
UBC
|
NBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
UBC
|
USP15
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
UBC
|
ZRANB1
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
UBC
|
NBR1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
NBR1
|
MAP1LC3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
MAP1LC3A
|
BNIP3L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20010802
7715597
|
NBR1
|
MAP1LC3A
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
PHB2
|
PHB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
ESR1
|
YWHAQ
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22329840
|
MTX2
|
EED
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
RAB7A
|
ATG9A
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21169990
8141833
|
TOMM70
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20628368
16394098
|
GABARAPL1
|
CALCOCO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
MTX2
|
MTX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17510655
17624330
|
TOMM20
|
TOMM7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PRKN
|
MFN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1231031
23620051
|
MARCHF5
|
MFN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219003
16936636
|
MFN2
|
PRKN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1231031
23620051
|
PRKN
|
MFN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25915564
29921586
|
MFN2
|
PRKN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25915564
29921586
|
FIS1
|
MARCHF5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16874301
5218876
|
PRKN
|
RHOT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
30504269
22396657
|
CHCHD6
|
MTX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
MTX1
|
SAMM50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
MAPK8
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
COX4I1
|
VDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
FOXO3
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
UBC
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
5216530
12857745
|
PHB2
|
VDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
809.0
|
0.81
|
STRING
|
36370105
|
TOMM22
|
TOMM40L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
811.0
|
0.81
|
STRING
|
36370105
|
CHCHD3
|
IMMT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
AMFR
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
TFE3
|
TFEB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
CHCHD3
|
SAMM50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
MUL1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
HTRA2
|
OPA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22939629
31617661
|
ESR1
|
HUWE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19805454
25604459
|
MYC
|
IMMT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
29467282
|
LACTB
|
IMMT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
31617661
|
APOOL
|
IMMT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27499296
33961781
|
IMMT
|
CHCH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27153535
17624330
|
IMMT
|
PHB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
34079125
|
MYC
|
RPS27A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.82
|
STRING
|
36370105
|
MYC
|
PHB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
35140242
29467282
|
MYC
|
CHCH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
29467282
|
MYC
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
20232342
|
HIF1A
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.82
|
STRING
|
36370105
|
AIFM1
|
SFXN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
27218139
|
PHB2
|
SFXN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
34079125
|
ESR1
|
MOV10
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33731348
31527615
|
MTX1
|
SAM50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17510655
34037656
|
APOOL
|
SAM50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27499296
33961781
|
APOOL
|
CHCH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27499296
33961781
|
APOOL
|
MTX2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27499296
33961781
|
APOOL
|
CHCH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27499296
33961781
|
MFN2
|
SAM50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29874585
27059175
|
CD244
|
CHCH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
MTX2
|
TRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
32877691
|
MOV10
|
MTX2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22658674
32877691
|
MOV10
|
RAB5B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22658674
22939629
|
CHCH6
|
SAM50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32296183
32877691
|
MTX2
|
BINCA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
MAP1LC3B
|
NBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
UBB
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
GABARAP
|
NBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
HUWE1
|
RPS27A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
MON1A
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
MON1B
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
ESR1
|
IMMT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33731348
19805454
31527615
|
CD244
|
IMMT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
ATF4
|
DISC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31413325
12812986
|
APOOL
|
SFXN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
27499296
29568061
34079125
|
CD244
|
MTX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CD244
|
BINCA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CD244
|
MTX2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CHCHD6
|
SAMM50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
MITF
|
TFEB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
DNAJC11
|
IMMT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
832.0
|
0.83
|
STRING
|
36370105
|
ESR1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
MYC
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
AIFM1
|
IMMT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
34079125
29568061
|
MYC
|
HIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28628118
15071503
28205554
|
TFEB
|
MITF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
16189514
26496610
33961781
9806910
|
TFEB
|
TFE3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
26496610
33961781
33519497
9806910
|
MAP1LC3A
|
NBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
HUWE1
|
UBA52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
UBB
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
GABARAP
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
NBR1
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
KRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
HIF1A
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25879517
19738058
11739718
|
MAPK8
|
JUN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
7148309
19527717
|
SRC
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
17284441
6169640
|
AIFM1
|
PGAM5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
34079125
27218139
29568061
|
RAB5A
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
RPS27A
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
JUN
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
UBC
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
EIF2S1
|
RPS27A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
MYC
|
HUWE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17314511
16269333
26279298
18488021
29467282
31677785
|
MYC
|
OPA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21150319
17353931
|
RAB7A
|
PHB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
31536960
26496610
|
APOOL
|
APOO
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
27499296
32877691
|
CHCH6
|
CHCH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
33961781
30021884
|
COX4I1
|
NDUFA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
CALCOCO2
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
DNAJC11
|
MINOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
MAP1LC3B
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
ESR1
|
FOXO3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
MAPK9
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
9405416
|
ESR1
|
FOXO3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
18312651
11435445
|
TRAF2
|
HTRA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20562859
31617661
33961781
33229071
|
IMMT
|
CHCH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
27153535
31536960
17624330
33961781
26666268
|
MYC
|
UBC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21150319
16996503
19131971
|
BECN1
|
AMBRA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
23974797
|
ESR1
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10681512
17656465
17312152
16651265
18765668
10446910
15084343
16439465
15637147
19652226
15705965
15987735
9611253
15557281
9328340
|
AIFM1
|
APOOL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
29568061
34079125
|
PGAM5
|
PHB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31536960
31177901
34079125
|
ESR1
|
PHB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10938099
24051437
12943695
26052702
17932104
19805454
28555617
10359819
15140878
|
RAB7A
|
VDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31536960
29360040
26496610
|
MTX1
|
MTX2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10381257
17510655
|
MTX2
|
CHCH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
32877691
26496610
|
MTX2
|
CHCH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
32877691
26496610
|
MTX2
|
MTX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
32877691
|
GABARAPL1
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
HIF1A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
MAP1LC3A
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
BNIP3
|
BNIP3L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
CSNK2A1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
RABGEF1
|
UBA52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CALCOCO2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
MINOS1
|
SAMM50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
PHB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
RELA
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
TAX1BP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
HRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
IMMT
|
SAM50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
27153535
34037656
32877691
17624330
|
OPTN
|
UBB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31723608
22101367
23414517
|
SMURF1
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
RAB7A
|
RAB5C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
26344197
|
RAB7A
|
RAB5B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10329441
26344197
|
TFE3
|
MITF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11818452
33961781
28514442
11930005
|
SAM50
|
CHCH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32296183
25416956
34037656
33961781
32877691
|
MTX2
|
SAM50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
34037656
26496610
33961781
32877691
|
HUWE1
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
UBC
|
USP15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
BECN1
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
MAPK8
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
CSNK2A1
|
CSNK2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
FUNDC1
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
C1QTNF2
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
CALCOCO2
|
MAP1LC3C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
MYC
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16713569
11274368
18003922
17418410
15780936
32115405
|
SP1
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25879517
10506225
16713569
33572115
16478997
17215518
|
JUN
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17317669
11477071
16713569
23747343
|
HIF1A
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12228247
17024177
17418410
15780936
|
MFN1
|
MFN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
27713096
33961781
19052620
|
AMBRA1
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
HRAS
|
KRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
AMFR
|
RPS27A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
TBK1
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
HIF1A
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
GABARAPL2
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
BNIP3L
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10467396
9973195
16189514
|
E2F1
|
MAP1LC3B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19657746
18408756
|
E2F1
|
BNIP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19088195
18096822
|
E2F1
|
LACTB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12629508
|
E2F1
|
RELA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24755270
|
E2F1
|
SIAH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20187294
18627426
|
YWHAQ
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15494392
|
SP1
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10547281
8657141
10850422
|
E2F1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19276347
21625432
|
E2F1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11564866
18319725
90001421
|
IMMT
|
DISC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
90000000
31413325
17043677
20880836
|
IMMT
|
MTX2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
17624330
26496610
33961781
32877691
26344197
|
MYC
|
NRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
TOMM20
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
PHB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11983916
12695333
|
MYC
|
UBA52
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
SQSTM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
PRKN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20638938
15078880
23277542
|
RELA
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12027803
16713569
|
MYC
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11274368
16713569
|
TP53
|
AIFM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23506862
16729031
|
TP53
|
PHB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16918502
14500729
21829624
|
ATF4
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
1827203
20936779
23661758
|
UBA52
|
PRKN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24784582
26161729
24856362
|
TBK1
|
OPTN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
18307994
6492190
|
OPTN
|
TBK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27086836
25923723
32556086
29395067
27035970
27538435
25803835
26365381
20174559
27620379
30327196
23414517
18307994
31723608
32707033
21903422
|
PINK1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20057503
|
RELA
|
BNIP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19088195
17082476
|
MITF
|
HIF1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15983061
22012259
|
HIF1A
|
BNIP3L
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19828020
20864819
|
HIF1A
|
CITED2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18158893
17499866
17022961
|
SRC
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24498420
14766010
15604093
11013076
27420286
29720121
12736255
18451880
15140878
23065768
17043237
17627277
7539106
11032808
17363140
20935677
14963108
11564893
12630920
22328528
15020686
15784253
17921256
24051437
10454579
17400812
17284441
16957778
|
SP1
|
SRC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10625617
19112177
|
ESR1
|
SRC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20160136
20460377
22865929
|
SRC
|
KRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
30644389
26854235
9096340
|
SP1
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14561739
16452190
9295358
|
SP1
|
CSNK2A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10849443
19027835
|
CSNK2A1
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14675149
25862939
|
RABGEF1
|
RAB5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11452015
27411398
19759177
|
EED
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
TBK1
|
CALCOCO2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19820708
21903422
|
MARCHF5
|
FIS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16874301
|
GABARAP
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
ESR1
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
RPS27A
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
NBR1
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
UBC
|
USP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
RPS27A
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
TOMM20L
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
UBB
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
TOMM20
|
TOMM40
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
BCL2L1
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
PINK1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
SMURF2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
CSNK2A2
|
CSNK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
UBA52
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
ESR1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
IMMT
|
SAMM50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
SQSTM1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
RABGEF1
|
RAB5A
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.92
|
0.92
|
Signor
|
11452015
|
RABGEF1
|
RAB5A
|
â—¼ GTPASE_REACTION
|
✅
|
+
|
0.92
|
0.92
|
Signor
|
27411398
|
MAP1LC3B
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
MAP1LC3A
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
AMFR
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
UBC
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
CSNK2A3
|
CSNK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
RAB7A
|
RAB5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
34079125
22939629
10329441
26344197
|
JUN
|
UBA52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
RABGEF1
|
RPS27A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
RABGEF1
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
IMMT
|
MINOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
SP1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
NBR1
|
RPS27A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
SQSTM1
|
MAP1LC3A
|
â—¼ COLOCALIZATION
|
✅
|
|
0.95
|
0.95
|
mint
|
19427866
7034152
|
TOMM20
|
TOMM22
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
UBA52
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
UBA52
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
RPS27A
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
RPS27A
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
E2F1
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10850422
10409740
8657141
10547281
8657142
|
UBC
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17568776
5220017
|
TBK1
|
TRAF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
14743216
32707033
20449947
20562859
29125880
23007157
27135603
30420664
33961781
10990461
30561431
21903422
32041822
|
RAB5C
|
RAB5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
17353931
26496610
33961781
34079125
|
BNIP3L
|
BNIP3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
10381623
6594431
|
JUN
|
MAPK10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
IMMT
|
MTX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
964.0
|
0.96
|
STRING
|
36370105
|
RAB5A
|
RABGEF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
HUWE1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
TOMM40
|
TOMM7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
MAP1LC3B
|
OPTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
BCL2L1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
OPTN
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
CSNK2B
|
CSNK2A1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
36833176
|
NBR1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
UBC
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
OPTN
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
AMFR
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
JUN
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
RPS27A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
RABGEF1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
RPS27A
|
UBA52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
TOMM22
|
TOMM40
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
TOMM22
|
TOMM7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
JUN
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
RELA
|
BCL2L1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
15079071
15536066
17550372
19171876
23430059
8383323
9743347
|
RELA
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10925251
17673602
14978135
20585448
15231833
14739605
10585435
20066113
16904634
9439816
10733571
15756023
15986355
21722408
12226754
15856023
16453001
18223231
19706766
|
TP53
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
22869582
9582400
9989972
11713584
18172861
23519249
12705879
9000137
11713302
|
MYC
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
14517295
18802399
16316993
17331788
|
MAPK8
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
10617621
25241761
15733859
12633850
18471544
|
FKBP8
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16189514
12510191
15733859
|
BNIP3
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16189514
10625696
|
TP53
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
24814347
12667443
16151013
26556313
14963330
16713569
20837658
24474649
21900206
|
PINK1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23953109
24013390
28486788
18974096
26188358
31367011
34064109
22617334
12633850
21840391
20363734
17369848
27398719
|
BCL2L1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
33931087
19180116
19049976
22219388
18628207
18641390
17659302
9765397
16713569
19713971
24443581
17446862
17337444
|
BCL2L1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
24814347
12667443
16151013
26556313
14963330
16713569
20837658
24474649
21900206
|
CSNK2A2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16083285
1088347
10348343
10884347
16552184
9315650
10747897
|
CSNK2A2
|
CSNK2A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
26186194
27705803
25519132
19011756
26496610
25852190
23455922
|
TP53
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21715977
20805247
8557038
11795482
17210690
22952705
|
ESR1
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22791811
20215421
12697671
10446910
|
SP1
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9054613
12697671
10446910
18440323
|
E2F1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8208548
2721961
7753559
11705881
24038073
8355712
1549358
1567856
12629508
|
E2F1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22241525
8557038
15706352
21441950
12675512
23954287
12625370
|
PHB1
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10523633
12065415
14637159
|
E2F1
|
EED
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18319725
14532106
|
E2F1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22480684
11739724
12625370
|
EIF2S1
|
EIF2AK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
18664456
12370288
16288713
17956313
11907036
10026192
|
EIF2AK3
|
EIF2S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
76.0
|
1.0
|
Omnipath
|
25429617
25579745
14967143
17998059
21981022
27009865
10504407
23356742
3352609
26622781
24316205
24706853
16288713
20408811
30070006
18840095
27638465
21844328
21029306
23293645
21901118
29199180
30081573
14638860
19007793
9819435
23935851
8099443
21029301
19220912
31226023
25660019
22509299
22169477
11337501
24904562
15314157
9930704
23314846
17998206
17325203
16179258
25393282
19583950
26028033
29396442
26487695
10542257
18694499
1677563
11555640
24705207
20040105
24159375
25541374
24958502
11907036
29163417
|
EIF2AK3
|
ATF4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19029953
15550948
|
HIF1A
|
FOXO3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
FOXO3
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24062311
16807346
16809346
17575143
|
FOXO3
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11435445
15367686
16807346
18312651
|
FOXO3
|
PINK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18644865
10783894
16288288
20673124
11094066
17646672
19276113
15509806
11994454
11154281
|
PINK1
|
HTRA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17906618
30013019
|
HUWE1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
26279298
16915296
34761308
16969074
|
HUWE1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
17145710
15989956
19918835
19960022
19590512
|
JUN
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
40.0
|
1.0
|
ACSN
|
11274345
11929833
11955436
11967263
12051714
15001769
15576399
15768032
15806138
16007074
16039586
16169192
16510874
17050667
17143292
17291450
17439715
17936032
18347071
18627596
19619488
19623618
20006983
20122174
20530697
20705860
20920541
21285352
21767405
22290435
22705350
22761862
23306204
23343194
24023259
25730849
26587781
7542250
8545107
8666229
|
MYC
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10432118
11274345
11283614
11875494
16327802
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21093321
21372296
21406394
21765015
2191300
22067385
22461508
23124025
23390297
25002027
|
JUN
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21835891
8276360
1774959
2498162
21607323
20410304
14523011
18037408
|
RELA
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12894581
18184402
7869034
17673602
12783888
11114727
17944672
9596659
19469019
21790895
19766095
17018379
8289784
18566231
|
HIF1A
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
20404562
23059786
19845622
18616527
15780936
21303984
|
SP1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11470523
9492315
2284094
8437848
7753559
8355712
2057364
|
ESR1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
22396492
21835891
15073177
18193094
11517191
21505052
22892083
8707895
19569049
14722073
18414489
|
MYC
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10962037
10656696
8494784
10348347
19882681
16557594
19086036
15780936
14519204
16112647
11781835
7969121
11789587
9839551
|
MYC
|
ATF4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12695333
23612979
|
JUN
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
15806138
16510874
22290435
18627596
19623618
11929833
23343194
15768032
22761862
17050667
16039586
20122174
17291450
20920541
17143292
20006983
17439715
15576399
21767405
23306204
8545107
22705350
18347071
16007074
16169192
21285352
20530697
19619488
11274345
|
MAPK9
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10551811
34160558
26235622
25893300
25438055
20140016
33928666
11243879
|
MAPK8
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
19651622
10551811
17081983
18767875
20068231
91332050
1651323
1748630
16713569
11243879
18669648
15210690
|
SP1
|
SQSTM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9762895
12736330
17012241
|
NBR1
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
20562859
29343546
16861740
20808283
15802564
24879152
25007327
19250911
12813044
21935636
|
GABARAPL1
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
17580304
20562859
23022382
21691068
25416956
31053714
16189514
32296183
21617041
19250911
|
MAP1LC3A
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
20061800
23022382
23459205
35044719
22963397
36036324
31053714
21045561
25921531
19250911
17580304
21628531
20204693
28740232
23640897
25686248
24100292
26075355
20562859
22658522
25984893
21460636
16286508
19427866
32296183
23989536
19021777
26268733
22714671
24998849
18653543
31366950
33436498
16169070
23239879
26754771
|
GABARAPL2
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
17580304
20562859
23022382
17353931
24582747
25416956
33436498
31053714
16189514
32296183
21460636
19250911
21900206
|
TBK1
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
24818040
25040165
29147513
28655770
31810986
28871090
25505069
32966780
27846364
31444413
27404485
34996837
32835772
24886973
30223576
29930914
29973599
27005665
22921120
25723488
25972374
33084718
|
MAP1LC3B
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
18083104
23022382
35044719
26413874
25416956
22434781
31053714
24023838
19250911
17580304
23333919
20452972
24668264
28085563
21900206
20562859
20010802
25007327
32296183
33302793
24582747
33436498
16169070
|
ESR1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20080630
16115928
22787161
12750288
20696891
17681750
17699779
|
HIF1A
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12542982
17390008
9537326
15780936
11696352
10469629
17236590
20706634
15629713
11007955
|
RELA
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18269916
10348347
11032029
8051093
20061391
15155458
21332394
9890939
21887328
|
JUN
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
22859294
17321721
20697347
10348347
12963547
10072388
22353755
18604200
|
TP53
|
KRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11514734
18555006
10953306
14741382
19107228
20124454
8274455
16061648
10448271
|
TP53
|
HRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21552926
9662334
11127813
21552928
|
TP53
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
19846904
15790310
11118296
11384995
21611785
7478550
15967108
18419600
19244234
9865734
18769160
|
TP53
|
SIAH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
20181957
20421190
14985507
11852084
|
TP53
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22607268
23376463
18374905
15958553
10854211
22353755
|
CSNK2A1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
53.0
|
1.0
|
Omnipath
|
23443559
15358769
9315650
19413330
11285227
11551930
11883897
22975381
11709713
16083285
1088347
33745968
16552184
10884347
10747897
10673501
7936649
12628923
25241761
21127074
16964247
24725084
10606744
10348343
10951572
|
CSNK2B
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10606744
11709713
10214938
10951572
16713569
11551930
10747897
10673501
11883897
|
MAPK9
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
12356735
14665630
26158765
18778462
12969974
12861053
15254178
17135248
18669630
12384533
17363488
17698850
11283254
10706102
21454683
18931691
11551930
11397945
14612532
15064747
15963507
11175334
11423984
27147566
29234486
24657168
10581258
14517211
17353187
10673500
22030623
14527925
22728651
17525747
15629715
9393873
11447225
15671037
22285752
17245430
15140942
28673515
23871434
11078726
20041275
11896587
16731759
17121812
33514736
11861384
25431954
12810724
17967874
12955074
21832239
16818520
12756247
23798621
11526498
20009884
16713569
10202145
11850826
11896572
10710310
10570149
12959929
15269203
11583595
21148320
|
PPP1CA
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
16501611
16713569
15231748
15178317
|
MAPK8
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
11108663
12531896
16713569
11283254
10706102
19651615
27147566
9724739
15538975
9732264
10581258
10436023
17570479
9393873
11896587
12514174
15580310
18813780
11078726
|
MAPK10
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9393873
16713569
14699954
|
TP53
|
SIAH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12077306
12438652
14985507
15326481
|
TP53
|
UBB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
18172499
18695251
24667498
22056774
17290220
17592138
12421820
18413597
20173098
19556538
21857681
17470788
18359851
19805293
19196987
12640129
|
TP53
|
PHB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24380853
16918502
20134482
14500729
16319068
16713569
|
TP53
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9537326
16713569
12124396
15629713
16882692
|
AMFR
|
VCP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
20126661
22328510
16407162
16987818
17681147
26712280
16275660
21636303
17872946
18835813
19828134
22119785
23333620
23383273
26424800
21343306
21914798
16186510
15331598
17311810
|
EIF2S1
|
ATF4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
12601012
12667446
16246152
23850759
|
NBR1
|
GABARAPL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
20562859
23022382
21620860
19250911
|
CSNK2A1
|
CSNK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
TBK1
|
OPTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
27247382
29246869
29594070
27035970
21617041
18307994
22364875
29755463
21903422
26376340
29867991
23794264
26101267
26365381
21862579
27538435
25026213
25923723
29282133
29626651
29971063
30294276
30223576
20174559
26266977
23414517
27086836
23178947
22518139
27906974
25803835
|
ULK1
|
GABARAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
20562859
17145710
17353931
22885598
11146101
23043107
31053714
25126726
|
NBR1
|
GABARAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20562859
23022382
21620860
24879152
19250911
|
AMBRA1
|
BECN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
21358617
22441670
23030059
23377657
23974797
|
VMP1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23316280
19056683
17940279
|
ULK1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
26390974
25545884
28301741
29734735
29233870
30292171
28518135
29313410
24191236
26546165
24848530
25026281
26921696
25026296
25373623
17595159
16940348
26108642
29371398
25891078
23685627
24370004
26008601
28238651
30397185
29233871
24834848
29867359
|
AMBRA1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
20562859
23974797
20711182
20417604
21358617
25438055
23954414
20921139
24587252
17589504
25499913
33562550
|
RELA
|
TRAF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15041463
19392652
21573233
15723831
9733516
|
SP1
|
HRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
8106522
8208618
3012774
11559711
21931711
8027084
1776841
|
SRC
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12695509
9626657
9020108
25157176
33413561
|
HRAS
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11525649
8137421
16810318
16713569
|
JUN
|
ULK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
11001584
11274345
16054035
16396903
16406505
16880536
17000779
17439715
17638910
18754008
18813803
19081070
19190345
19219074
20107231
22354771
23031257
26587781
8545107
|
ESR1
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11477071
17963131
10037443
16679312
|
SP1
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20148354
8355696
8892460
1406636
19437621
9054614
17502875
|
JUN
|
SRC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7499226
16798740
23533633
14736735
18216279
|
MAPK9
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
17143273
17145710
17637567
12584171
20506250
11948398
15378002
16824735
9687508
8654373
20028971
12788955
9305638
15302935
26091349
33822843
18362184
17875713
16393692
9405416
17570479
1922387
18252863
25561726
7737130
10490605
17189706
11896587
34408980
11274345
20178741
8525045
16076903
7992057
19527717
7600582
17215518
8985011
11801649
19118012
11278395
8001819
8137421
19436832
16533805
8945519
12881422
9315636
10385525
12093796
14523011
19910486
15212693
8157646
12040039
11562357
|
ESR1
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11477071
17317669
16713569
|
CSNK2A1
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
25609649
1846781
11948398
15378002
12531896
19413330
8654373
15302935
11075956
12628923
11896587
1516134
8464713
11971971
1651323
8137421
9685505
91332050
|
RELA
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18174238
9468519
16713569
10488148
|
MAPK10
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17143273
20506250
16824735
8654373
20028971
16007099
21988832
12167088
16393692
1922387
16076903
22327296
19527717
21757544
19436832
17670986
14523011
11274345
20395206
11562357
|
MAPK8
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
202.0
|
1.0
|
Omnipath
|
17143273
17804415
10617656
8846788
15958389
11948398
10882101
20028971
12697749
15894542
20514406
14612408
17875713
9891069
17570479
18922473
11809792
8586671
11896587
12185592
12871843
7992057
7600582
11278395
8137421
8001819
10493750
14557262
16549498
18707149
9169478
11460167
15289320
8157646
16007099
20506250
22110360
15378002
9687508
12740383
20732415
9305638
19270716
23331499
10747973
16291755
16393692
12832416
18988627
10713700
18669648
12087092
14633987
8525045
15677475
16076903
16166642
18650425
15590691
1608942
19910486
18212344
11562357
12228228
16740711
14701799
19690332
10871633
12531896
16713569
8654373
16983342
19664995
15302935
10962563
15068801
8621542
8607977
18362184
10393177
20068231
9808624
14572659
8224842
10585392
9407028
17363973
19527717
19436832
14517282
12407442
9487126
9692890
14523011
15212693
10908726
11108663
13130464
10064600
18429822
15299005
9774977
11907583
12963725
16824735
19413330
10617104
17055484
21071413
18452278
16434970
16157600
7737130
23816567
10987838
17189706
9561845
9575168
1460037
7652575
18617513
24113186
11971971
11801649
25098452
20058876
16533805
9184210
18003900
9315636
10385525
18957422
12881422
11274345
12052834
15749833
|
JUN
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11477071
17317669
16713569
|
AIFM1
|
NDUFA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
AIFM1
|
NDUFA4
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
AIFM1
|
NDUFA4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
PINK1
|
RHOT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
22078885
29700661
24671417
28556983
25611507
24647965
22396657
|
PINK1
|
MFN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
29971063
24328763
29674596
25132912
28190190
26992930
26611876
|
PINK1
|
PRKN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
93.0
|
1.0
|
Omnipath
|
25216678
27906179
19229105
26162776
25847540
29183391
26116755
33730565
26707701
25474007
25365205
25548534
25595529
29372317
24184327
25611507
22724072
20398440
26471730
28626500
29422536
27453777
24962176
24751536
26631732
22944659
17052189
25375667
25088558
33827825
27554669
24357652
24647965
24671417
29660402
30063295
27528605
23256036
29883688
23933751
23670163
23319602
25505445
25849928
23754282
20418918
19966284
25697646
32983119
30012094
34166935
29809156
24901221
28323427
25284222
29689231
30404819
19358826
19880420
20126261
26254304
20966070
29950828
20798600
29991771
24660806
30290272
25611391
25712550
29899409
28920079
25591737
29475881
29337137
|
PINK1
|
UBC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24784582
25857750
|
PPP1CA
|
EIF2S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21622569
9694816
9023344
12941928
|
SP1
|
RELA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7636984
8450395
9151857
20538607
11964305
|
RELA
|
HIF1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18498249
17898080
23185316
|
CSNK2A1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
34049972
15016307
10938077
27630163
|
TBK1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
12842894
17562815
15128824
15485852
10521409
15489227
15849198
14560022
19958770
12767944
|
RELA
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12055073
7933095
10671503
20861353
|
HIF1A
|
BNIP3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
HIF1A
|
BNIP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20864819
17848618
11559532
20332243
19745228
17513511
11550088
10922063
12879018
|
HIF1A
|
BNIP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16585195
19136941
18054315
11559532
|
SRC
|
FUNDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
25810907
27757847
29370689
24903109
27995894
26258123
29951054
26501336
29278362
22267086
|
SRC
|
RRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17474147
15212693
10570155
11682467
|
SRC
|
ATG9A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
27934868
|
SRC
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
15784253
25364741
17400812
16957778
17627277
15140878
11032808
23065768
12736255
7539106
17921256
27472465
14963108
24487689
25275301
12630920
22865929
14766010
30148069
11013076
15020686
9500442
17284441
|
SP1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12237165
19351845
11345900
21235772
23209644
12429135
18006846
10982795
22622808
15691879
21191649
|
SP1
|
UBC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19733223
17409431
11872750
|
MAPK8
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
28831131
22266860
18199680
19245816
25398907
17570479
|
CSNK2A1
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
9153193
|
ULK1
|
AMBRA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23524951
25438055
20921139
|
UBC
|
PRKN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
24784582
26162776
26161729
25847540
24751536
26254304
23670163
26116755
27284007
25474007
26260794
22724072
25969509
24856362
|
NBR1
|
MAP1LC3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23022382
21620860
19427866
19250911
21935636
|
PHB2
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15140878
17932104
26052702
10938099
12943695
|
CSNK2A1
|
MAPK9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11062067
|
CSNK2A1
|
FUNDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
27757847
24746696
29540794
30591555
27653272
25126723
|
CSNK2A1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11139588
26703694
9337862
20043841
11432835
11507039
9528769
7838153
|
MAP1LC3B
|
NBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
20562859
23022382
21620860
24879152
19250911
|
MAP1LC3C
|
NBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20562859
21620860
19250911
23022382
|
NBR1
|
GABARAPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
20562859
21620860
19250911
23022382
|
RAB7A
|
MON1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
Reactome
|
20851765
23084991
23220125
27246931
12364329
11179213
2115402
23351085
20305638
8522602
12944476
25341920
23645161
21683469
9020161
15138286
20797862
20434987
|
RAB7A
|
CCZ1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
Reactome
|
20851765
23084991
23220125
27246931
12364329
11179213
2115402
23351085
20305638
8522602
12944476
25341920
23645161
21683469
9020161
15138286
20797862
20434987
|
BNIP3L
|
GABARAPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19363302
20010802
|
ULK1
|
FUNDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
25810907
27757847
24671035
29233870
29370689
25858070
29951054
25818167
|
MAPK9
|
MFN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
22748923
|
ULK1
|
ATG9A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
25266655
27934868
|
PRKN
|
TOMM70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24244333
24149440
23068103
23503661
25591737
|