HDAC1
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17980157
18319725
|
MYC
|
HDAC2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20697349
|
ESR1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
3677090
|
MYB
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15082531
|
AR
|
TP63
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21303954
20610535
|
H3-4
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
KLF3
|
KLF8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18687676
|
ESR1
|
MYB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18414489
|
MYB
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12096342
18945670
|
HNF4A
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16474850
12466965
|
KLF3
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
H3-4
|
GATAD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
MYB
|
PAX6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9371644
7838532
|
ESR1
|
SIN3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16469706
31527615
|
RBBP7
|
KDM5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
24981860
|
RBBP7
|
PHF12
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
26496610
26841866
33961781
24981860
26186194
|
HDAC1
|
EMSY
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
23752268
26496610
26841866
33961781
|
HDAC1
|
KDM5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
23752268
33961781
26496610
|
PHF12
|
HDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26841866
24981860
26496610
|
HDAC2
|
EMSY
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
23752268
24981860
26841866
|
PHF12
|
KDM5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26841866
24981860
26496610
|
PHF12
|
SIN3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26841866
33961781
26496610
24981860
|
PHF12
|
EMSY
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26841866
24981860
26496610
|
KDM5A
|
SIN3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
17573780
33961781
26496610
24981860
|
SIN3B
|
EMSY
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26841866
33961781
26496610
24981860
|
KDM5A
|
SIN3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
830.0
|
0.83
|
STRING
|
36370105
|
MTA2
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
6613464
18451879
|
ESR1
|
MTA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
18451880
16645043
|
MYC
|
SIN3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
24951594
30415952
|
ESR1
|
RBBP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18577416
23403292
21182205
31527615
|
C11orf30
|
MORF4L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
HDAC1
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
MYC
|
HDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17314511
20195357
22286234
30415952
|
RBBP7
|
SIN3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
27705803
26496610
33961781
24981860
26186194
|
GATAD1
|
MORF4L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
GATAD1
|
RBBP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
HDAC2
|
SIN3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
E2F1
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10734134
9468140
17980157
26468294
9468139
|
RBBP7
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
24981860
|
PHF12
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
23752268
11390640
26496610
26841866
33961781
|
NFYC
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10446203
11282029
|
HDAC2
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
HDAC2
|
SIN3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15935060
26949739
21258344
24981860
16464847
|
KDM5A
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11358960
31527615
|
GATAD1
|
KDM5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
PHF12
|
RBBP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
GATAD1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
E2F1
|
MYB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10567569
8137237
18319725
|
E2F1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11564866
18319725
90001421
|
MYC
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17314511
18271930
34147029
26496610
30415952
18003922
22286234
24951594
|
YY1
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
18490439
19219071
2191300
|
MTA2
|
RBBP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
31980649
19703393
22939629
20714342
14645126
10444591
27705803
28179136
33961781
24981860
26186194
12920132
11297506
|
TP63
|
KLF12
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17521434
|
HDAC1
|
YY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18634613
11486036
11940654
|
ESR1
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17312152
31527615
24051437
33731348
14722073
21182205
15557281
18451880
14506733
15140878
|
HDAC1
|
SIN3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
23752268
11959842
20585571
10357820
15935060
10444591
26496610
33961781
11102443
24951594
26344197
|
MTA2
|
HDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23752268
31980649
19703393
22939629
30737378
20714342
26949739
10444591
21258344
24981860
12493763
19686092
11102443
12920132
18451879
11297506
26344197
|
ETS1
|
MYB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7848925
8999884
|
KDM5A
|
MORF4L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
HDAC2
|
PHF12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
RBBP7
|
SIN3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
MORF4L1
|
RBBP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
KDM5A
|
PHF12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
HDAC1
|
MORF4L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
HDAC2
|
MORF4L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
HDAC1
|
PHF12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
MTA2
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
6613464
18451879
|
HDAC2
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
26949739
|
HDAC1
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
958.0
|
0.95
|
STRING
|
36370105
|
HDAC1
|
SIN3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
HDAC2
|
RBBP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
22939629
20388487
27705803
21258344
33961781
24981860
26186194
15451426
12493763
9885572
26344197
|
RBBP7
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
19703393
10444591
21258344
11102443
9885572
17255935
10471499
26496610
25885317
22939629
9150135
23752268
9790534
27705803
33961781
26186194
19686092
15451426
12920132
26344197
|
HDAC2
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
25241761
9520398
11287668
19703393
30737378
17894944
10444591
11466315
11777905
21258344
15297431
17956988
11102443
9885572
12032298
19041848
26496610
22416134
12493763
11739383
10581039
11804585
11564889
21670149
22939629
9150135
11919195
23752268
18059533
16713569
9804427
20388487
9790534
26949739
24981860
33961781
15987735
19182791
15451426
12920132
26344197
|
HDAC1
|
MTA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
31980649
19703393
10444591
21258344
12374985
17956988
11102443
27068747
26496610
20127688
11171972
11297506
20585571
21670149
11602581
22939629
18451879
23752268
9790534
26949739
16645043
22863883
28179136
27173435
24981860
33961781
19686092
12920132
26344197
|
MORF4L1
|
SIN3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
PHF12
|
SIN3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
HDAC2
|
RBBP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
HDAC1
|
RBBP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
HDAC2
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
MORF4L1
|
PHF12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
MTA2
|
RBBP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
ESR1
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22791811
20215421
12697671
10446910
|
E2F1
|
MYB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10567569
7929342
7565760
15867358
16299810
8137237
|
E2F1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
21966451
17178887
22508987
21099110
21099103
|
E2F1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8208548
2721961
7753559
11705881
24038073
8355712
1549358
1567856
12629508
|
KLF8
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
23.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
15576399
16039586
17143292
17306568
17666529
17671186
17936032
19619488
19623618
20705860
21151179
21285352
22290435
22761862
23343194
24023259
25730849
7542250
8666229
|
MYB
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18408764
19609274
8382794
1679531
1588953
1594249
9596659
11259163
8474446
2233716
16088151
|
HNF4A
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12591729
23714368
19966299
15024077
|
YY1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
9797456
16314465
10528225
8266081
19279113
17287852
10713181
18490439
17434929
16878156
18542060
|
ESR1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
22396492
21835891
15073177
18193094
11517191
21505052
22892083
8707895
19569049
14722073
18414489
|
HDAC1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21734722
17666529
15576399
22761862
22290435
19923891
20682799
|
YY1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8266081
15805285
18490439
19219071
2191300
|
MYC
|
NFYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11282029
10446203
|
HDAC2
|
YY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
9016636
19139378
11486036
8917507
|
HDAC1
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
HDAC2
|
â—¼ SHARES_COMPLEX
|
|
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
HDAC2
|
â—¼ UP_REGULATES
|
✅
|
+
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21655924
23242655
18316616
20101232
|
HDAC1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11994312
16713569
15640443
12612053
10428808
|
ESR1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8299561
11000528
22391641
|
AR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
12389206
11032808
16713569
11000528
18988627
|
HNF1B
|
HNF4A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10518495
8290348
11585914
16479257
|