Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CRK ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
CFL1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RAD18 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHPT1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
UBE2V1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 VPS4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ERBB3 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
DCTN6 DYNLRB1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
DNMT3L PHPT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PHPT1 KCNN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0803678105 18796614
NEDD8 UBE2K â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBB2A PAFAH1B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBE2V1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1551980 11057907
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
CRK PFN1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
DENR PSMD9 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CHMP4A CHMP5 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
NEDD8-MDP1 UBE2NL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
DBI PEBP1 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
NUBP1 NUBP2 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ARPP19 SZRD1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
TUBB4B UBE2V1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
UBE2N UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
NAA10 NACA â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
UBE2NL UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
TUBB2A TUBB4B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
ERBB3 PPM1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28065597 31980649
PARK7 MIF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
VHL MIF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21942715 17353931
PARK7 PPIA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31536960 29128334
PEBP1 STMN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 31980649
BLOC1S5 DTNBP1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
TUBB2A TUBB4B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
BLOC1S3 DTNBP1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
EIF4H SZRD1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RAD18 RANBP1 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
GMFB PPM1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
PPM1A PPM1B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PFDN1 PFDN5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CHMP4A VPS4A â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
EIF5A PFN1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
NEDD8 VHL â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PFDN1 PFDN6 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
PFDN6 VBP1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
TRAF6 UBE2L3 â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
NUBP1 NUBP2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
RANBP1 UBE2L3 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PFDN5 VBP1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
VHL NEDD8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11024059 17353931 18323857 16503656 15060148
VBP1 VHL â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TUBB3 TUBB4B â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
VPS4A VPS4B â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
PFDN2 VBP1 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
TRAF6 UBE2V1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
BLOC1S5 DTNBP1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
PFDN2 PFDN5 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
SGTA UBQLN2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
NEDD8 UBE2D2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
UBE2D2 UBE2K â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
UFM1 ARHGDIA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ARHGDIA UBE2R2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RAD23B DBI â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EIF5A DOHH â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 3.0 0.9 Reactome 17213197 16533814 14622290
UBE2N RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2V2 RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2L3 UBE2V2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PFDN2 PFDN6 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
NUBP2 NUBP1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 33961781 22863883
RAD18 PGK1 â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
UBE2M NEDD8 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 19713960 7294536
PFDN5 PFDN6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
PIN1 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
TUBB2A TUBB3 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
VPS4B VPS4A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 11563910 26186194 12594041 28514442
IKBKG TRAF6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
BTF3L4 NACA â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UBE2N UBE2NL â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
NEDD8 UBE2M â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CNOT4 UBE2D2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RAD18 PHPT1 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
TRAF6 UBE2N â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PFDN1 PFDN6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN1 VBP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN1 PFDN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN1 PFDN5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN2 VBP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PFDN5 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN5 PFDN6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN6 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NME2 KCNN4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17157250 18796614
TRAF6 IKBKG â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18180283 18347055 21220427 16547522
TRAF6 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17562858 17728323 17947236 14695475 18180283 15620648 15125833 12867425 11057907
UBE2N TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 18710948 1551980 17327397 11057907 15147900 18981220 21113135 17709375 31074699 19549727 18617513 24610907 27791197 29432170 19465916 23885119 15327770 27173435 21872579 25548215
VHL UBE2D2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215
RAD18 UBE2N â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
RAD18 ACP1 â—¼   KO_UP_REGULATES ✅ + 1.09 1.09 PKG 28854368
RAD18 NUDCD2 â—¼   KO_UP_REGULATES ✅ + 1.18 1.18 PKG 28854368
RAD18 CHMP5 â—¼   KO_UP_REGULATES ✅ + 1.31 1.31 PKG 28854368
RAD18 NUTF2 â—¼   KO_UP_REGULATES ✅ + 1.37 1.37 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368