Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
BCL6 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22422878 19487462
EIF2AK3 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16595687
EIF2A ATF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18471544
ATF6 DNAJC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12601012
ATF6 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9837962
EIF2AK3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19029953
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
EIF2AK3 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19029953
BIRC3 RIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21931591 19464198
DNAJC3 EIF2AK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25329545 12446838
EIF2AK3 SLC7A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19029953
HSP90AA1 RIPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CANX RPN2 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
RAC2 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SCN3B NF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HLA-DRB1 HLA-DRA â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5220278 7477400
AKT1 FAS â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25640309 31980649
ATF4 NFE2L2 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
EIF2S1 EIF2S3 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
EIF2AK3 HSPA5 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
BIRC3 RIPK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19464198 9705938 21931591
RIPK2 BIRC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16189514 21931591 19464198 9705938 30026309 9642260
NFE2L2 ATF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21087962 23618921 20185790
HSPA5 ATF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18624755 31226023
HLA-DRA CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
EIF2A EIF2S2 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ILF2 ILF3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
RAC3 SOD1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
RAC2 SOD1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
ILF3 ILF2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 17389650 11739746 26472337 29395067 22939629 21969602 26186194 20808282 23986595 28514442 16189514
HLA-DRA HLA-DRB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
AKT1 RHEB â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17517883 17277771 18372248 12524439 17386266
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
AKT1 ILF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20870937 18097023
EIF2S3 ATF4 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 ATF4 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 ATF4 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2AK3 ATF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19029953 15550948
ATF6 HSP90B1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17991856 18360008 23850759 26587781
ATF6 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 19667116 22189555 10856300 19622751 20165829 10866666 17117415 12076252 14973138 15899857 17241871 20801537 11256944 16452489 17522056 10564271 12713871
BIRC2 RIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19464198 16189514 21931591 9642260
EIF2AK3 EIF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25329545 15314157 16595687
EIF2S2 EIF2AK3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 18664456 12370288 16288713 17956313 11907036 10026192
EIF2S3 EIF2AK3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 18664456 12370288 16288713 17956313 11907036 10026192
EIF2S1 EIF2AK3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 18664456 12370288 16288713 17956313 11907036 10026192
HSPA5 EIF2AK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17145710 28534368 18624755 11907036 31226023
EIF2AK3 EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 76.0 1.0 Omnipath 25429617 25579745 14967143 17998059 21981022 27009865 10504407 23356742 3352609 26622781 24316205 24706853 16288713 20408811 30070006 18840095 27638465 21844328 21029306 23293645 21901118 29199180 30081573 14638860 19007793 9819435 23935851 8099443 21029301 19220912 31226023 25660019 22509299 22169477 11337501 24904562 15314157 9930704 23314846 17998206 17325203 16179258 25393282 19583950 26028033 29396442 26487695 10542257 18694499 1677563 11555640 24705207 20040105 24159375 25541374 24958502 11907036 29163417
EIF2AK3 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22558124 28104575 24641954 14517290
EIF2S1 EIF2S2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S3 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2S3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2S3 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
NFE2L2 SOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22493435 24417315 22245129