CASP3
|
DCC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11248093
|
CASP3
|
EIF2S2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10672017
|
CASP3
|
EIF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10734073
|
ESR1
|
EP300
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16704985
11279135
|
EIF2A
|
ATF4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18471544
|
ESR1
|
TGFB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12580758
11159847
|
EIF2AK2
|
EIF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16288713
15314157
|
GML
|
EIF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ESR1
|
MARK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19805454
31527615
|
DNJA2
|
EIF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
33957083
|
FIBB
|
EIF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SNX21
|
EIF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
FGF9
|
EIF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SSA27
|
EIF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SNR27
|
EIF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
T2EB
|
EIF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
EIF2A
|
E2AK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32938586
22268531
|
ESR2
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11500849
18765668
|
ESR1
|
EIF3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
30573685
19805454
31527615
|
SPB5
|
EIF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CP1A1
|
EIF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CP1A1
|
E2AK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
EP300
|
ILF3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
20808282
33742100
|
TGFB2
|
TGFB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
27684187
11483955
33961781
11157754
|
E2AK2
|
EIF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
29070839
19229320
22268531
|
EIF2S2
|
RPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
ESR1
|
PAIRB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33731348
31527615
20348541
|
ATF4
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
14630807
17872950
10350644
12471036
16219772
|
EIF2A
|
RS24
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
22863883
|
EIF2A
|
PAIRB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
22863883
|
PAIRB
|
RS24
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
22863883
|
ESR1
|
ESR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
TGFBR2
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
8044119
21054789
|
EIF2AK4
|
EIF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
25329545
16595687
|
EP300
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19887647
11782371
12738788
25728767
11867769
12479814
23065768
15308690
20388208
14761960
22227247
8799122
20348541
23403292
12714702
11581164
16713569
19838210
18765668
16645043
30418174
12574227
|
ATF4
|
EIF2AK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23009153
21146245
17141186
|
ESR2
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29509190
12630920
17991765
21182203
19022902
10706629
19746436
9473491
|
ILF3
|
E2AK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10320367
11438540
10684936
10400669
11438536
17079286
32707033
23455922
|
EIF2A
|
EIF2S2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
EP300
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
EIF2A
|
EIF3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
TGFB3
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
EIF3B
|
RPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
EIF2S2
|
EIF3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
TGFB3
|
TGFBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
TGFBR1
|
TGFBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
ABL1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20841568
20101225
30692633
|
CASP3
|
DCC
|
â—¼ CLEAVAGE
|
✅
|
|
4.0
|
1.0
|
Reactome
|
11248093
16158190
15310786
9796814
|
EIF2S2
|
EIF2AK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
18664456
12370288
16288713
17956313
11907036
10026192
|
EIF2AK3
|
ATF4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19029953
15550948
|
EIF2AK3
|
EIF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
25329545
15314157
16595687
|
EIF2S2
|
ATF4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
12601012
12667446
16246152
23850759
|
TGFB1
|
TGFBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFBR2
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR2
|
â—¼ SHARES_COMPLEX
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFBR2
|
TGFBR1
|
â—¼ SHARES_COMPLEX
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFBR2
|
TGFBR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB2
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
8106553
1310899
23331499
21071413
12729750
16446785
12809600
11157754
|
TGFB1
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
122.0
|
1.0
|
Omnipath
|
1310899
22874531
8047140
11279127
22710166
7878020
16424049
17673906
24132110
18922473
22943793
12729750
16446785
20519943
7706250
15761153
7594497
15548370
15761148
15265520
19010789
26194464
7852346
12717440
17768418
19050695
11133108
14557817
11278410
19920116
22949611
22703233
23331499
23070005
20060931
17070508
21614932
1333888
10716993
16572188
20860622
11323414
21900405
12724770
8106553
23034983
26192618
2871107
12809600
11382746
21372296
20538542
16200688
11792802
26201938
24403530
15099563
11013220
17979848
21054789
23784029
15003992
20644162
8515656
7935686
11157754
20856203
18382895
15282297
18855897
9865696
21441952
10678166
16127449
21041659
10026191
22315516
12767520
17404308
19732719
20616810
21071413
17934056
12738796
18423981
21098712
19747910
9311995
15034927
11274345
12154066
18758450
24336330
21278795
26966341
9261125
16474430
15653932
18490733
8242742
19038247
19109155
|
TGFB3
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
17145710
15017149
18243111
23331499
21071413
23180781
7878020
11850637
18988627
12729750
16446785
11157754
8106553
21423151
9872992
11382746
29170498
|
TGFBR2
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
48.0
|
1.0
|
Omnipath
|
7774578
9463378
19556242
8047140
23868260
18243111
7890683
10026191
23331499
8576253
21071413
7878020
21791611
10716993
18988627
11278251
19758997
25825445
22802914
16446785
11483955
8947046
11323414
11124802
15221015
11102446
11387212
12809600
7566156
26194464
|
TGFB1
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR1
|
â—¼ SHARES_COMPLEX
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
22326956
10187774
7852346
22703233
12809600
7706250
11323414
8047140
8235612
26194464
|
TGFB2
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
22326956
10187774
7608141
11157750
12809600
11157754
|
TGFB3
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
10187774
21423151
11850637
12060054
18243111
12607775
|
ESR2
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
14754635
24284820
15207704
18784357
11566442
12630920
22820289
19001520
18511514
14676837
19207817
22622808
21763263
18339713
15087130
|
ESR1
|
CYP1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16972788
16010691
17511620
15858227
15837795
20716622
22837390
|
ESR1
|
ESR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
12630920
9473491
19746436
21182203
10706629
10022879
|
EIF2AK2
|
ILF3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11438540
10400669
10684936
11438536
10320367
|