Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NFKB1 COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11277268
SP1 COL1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19558215
E2F1 SP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18342022
E2F1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9368006
SP1 COL1A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114293 11013220
LEF1 MSX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17068080 14551209
P4HB COL10A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211722 10436013
PPARG COL10A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20414969 16023420
GLI2 COL10A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22072985 17328886
GLI3 COL10A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22072985 17328886
SP1 COL10A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9497390 15849196
SP1 SLC3A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17023546
EGR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12011097
GLI2 COL5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14691458
SP1 EGR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20121949 7384875
SP1 ATP1A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24219545 15462673
SP1 MME â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14510963
SP1 COL18A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11093745
FOS COL3A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8206947 1903195
FOS COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10639331 10914841
FOS SP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18342022
FOS NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20188076
SOX9 RUNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605170103 17142326
TFAP2A SOX9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14969394 12511599
SOX9 COL9A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12399468 17264118
SOX9 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19306868 20593410
SOX9 NKX3-2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19306868
P4HA2 P4HA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RUNX2 LEF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20890621 19650108
LEF1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16575901 16043491
NKX3-2 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15703179 19306868
RUNX2 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11331591 16029574
SP3 ELN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8910531 12055073
SP3 ATP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10811658 24219545
PPARG SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18509005 24735796 20360975 22282354 18310298
SP3 SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15247906 11517158 10825178 16734381 9329821 12414801 12200149 23825960
COL10A1 VSNL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
SLC3A1 SLC7A9 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
C1QL4 SGTB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
EGR1 SP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20121949 12569082
PPARG SP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
C1QL4 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
COL8A1 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
SP1 NFKB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18083845 16740634 33572115 7933095
P4HA2 P4HB â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
RUNX2 FOS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11641401 11274169
COLGALT2 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
SP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10547281 8657141 10850422
E2F1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15711575 12110166 18319725
SP1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23843607 20160399 23704280
SIRT1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15850715 21633182
P4HB COL1A2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9545296 3173483 9560306
EGR1 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12729460 16702209 11169739
NFKB1 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10201951
BHLHE40 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15975549 22610404 11879638
DLX5 MSX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16189514 9111364
MSX2 DLX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16189514 9111364
PPARG FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10678274 23657115 18059282
SP1 ELN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12055073 21880723 7896792
SP1 COL5A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7646438
SP1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20427719 20538607 9151857
SP1 COL7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10980546 9092567
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
EGR1 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18044710 12637574
EGR1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9053449 10671503
NFKB1 KCNN4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 21725609 23178297 23572150
CEBPZ SOX9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15908194
CEBPZ COL11A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12805369
COL3A1 P4HB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9545296 3173483 9560306
SP3 TFAP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19481140 22827437 14744778
COL10A1 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
COL1A2 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
COL9A2 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
COL4A1 COL4A2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
DLX5 MSX2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16189514 9111364
ATP1A1 FXYD2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
E2F1 SP1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10850422 10409740 8657141 10547281 8657142
ACE2 SLC6A19 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ATP1A1 ATP1B1 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
SP3 COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9666093 10082137 17698844
RUNX2 COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23159876 11106645 11331591 24404380
SP1 COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 10091149 16575855 9666093 10775443 12138160 11348466 17698844 16564026 10082137 7504695 7590335
P4HA2 COL1A1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL1A1 P4HA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL1A1 P4HB â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL1A1 P4HA1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
SP1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9054613 12697671 10446910 18440323
E2F1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15711575 12110166 20971808
SP1 COL1A2 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
SP3 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9242631 9278495 10771485 11511308
SP1 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 20429888 8182090 12760745 16319104 8524247 11348466 16564026 9242631 11114293 22049076 9278495 9143363 10771485 11278686 9882423
P4HB COL1A2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
P4HA2 COL1A2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL1A2 P4HA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL1A2 P4HA1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
MSX2 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15383550 11683913 16115867 17060321
P4HB COL10A1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
P4HA2 COL10A1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
P4HA1 COL10A1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL10A1 P4HA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
EGR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 29212876 12011097 22455954
PPARG SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16269451 15111490 15908479 11777901
PPARG RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12878983 18715135 20589837 12704187
GLI3 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 21234400 20562908 9216996 19032343 12435627 16406505 19114989 16880536 16054035 11001584 17000779 16169709 16413481 15087129 16396903 19809516 20107231
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18044710 11447232 12888570 18065760 16650379 12637574
SP1 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20427719 18044710 9282327 8349585 10826704 10082539 12637574
SP1 SLC9A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12464626 16464174 19064501 16760259 21600882 19303862 11841999 17540780
SP1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17626239 10082538 9528985
EGR1 SLC9A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21600882 16464174 21537610
P4HA2 P4HB â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
P4HA2 COL3A1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
DLX5 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22298955 17060321 15383550 24355298 21187071 12815054 17335796 24692107 16115867
COL3A1 P4HA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL3A1 P4HA1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL3A1 P4HB â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
SP3 SLC9A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12464626 16464174 16760259 19303862 17344314 19064501 17540780
SP3 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18065760 11447232 12888570
P4HB P4HA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
P4HB P4HA1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733