BRCC3
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19202061
0807485106
|
TP53BP1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15970701
21914189
|
PARP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7986053
19779455
|
PARP1
|
SUMO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7986053
19779455
|
SUMO2
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22661230
22635276
|
ZRANB1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
UBC
|
ZRANB1
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
UIMC1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
25252691
|
PARP1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
34079125
25252691
26831064
|
TP53BP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
SUMO2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
20016603
20016594
22689573
21693764
21147198
|
SUMO2
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
19471022
21693764
32786267
25027693
21252943
19779455
|
BRCC3
|
BARD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
14636569
17664283
17525341
|
BRE
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
BABAM1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BRE
|
FAM175A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
SUMO2
|
UIMC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19471022
23211528
32786267
22689573
21693764
26719330
|
BARD1
|
UIMC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19615732
17525341
|
UIMC1
|
BRE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21282113
19261749
19261746
19261748
17525341
20656689
19015238
19615732
|
BABAM1
|
FAM175A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
UIMC1
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
18077395
19305427
21282113
19261749
19261746
23264621
19261748
19202061
17525341
20656689
19015238
19615732
|
BRE
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14636569
22990118
25184681
29656893
|
BRCA1
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19305427
17664283
19202061
22990118
25184681
14636569
25252691
29656893
|
BRCA1
|
UIMC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21622030
17525340
25184681
17525341
17643121
29656893
19305427
26446986
25252691
26027929
28569838
19766185
19261748
34408138
29499138
19615732
17525342
17621610
31932421
24085845
|
BRE
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21282113
19261749
19261746
30755420
19261748
17353931
20656689
14636569
33961781
20032457
19615732
|
SUMO2
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
BARD1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12431996
17525341
29367421
27977889
19916563
12732733
10477523
20060929
23680151
8944023
22110403
12951069
23086937
14638690
27239795
29355525
9788437
11925436
11257228
24289923
14647430
19176389
15184379
9738006
16403807
29180510
11278247
33589814
15265711
15159397
34408138
16713569
19117993
20681793
16391231
11301010
16489000
23416467
17664283
15569676
29858377
19369211
18493658
29656893
20351172
28398198
12485996
32347575
19766185
14636569
10026184
12700228
31270457
11573085
11526114
24085845
25823446
33961781
32092106
18936166
28514442
20215511
25184681
26490435
28948225
12890688
12438698
28262780
26831064
9342365
10635334
15855157
11504724
11773071
25252691
9798686
26350354
21901007
24695549
12887909
17873885
11498787
27454289
11927591
24981860
25652403
25634209
|
BRCC3
|
BRE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
BABAM1
|
BRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
UBC
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
UBC
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
BABAM1
|
BRE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
BARD1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
BABAM1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19261748
19261749
|
BRCA1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19342239
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
FAM175A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
BRCA1
|
BRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
UIMC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
BRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19342239
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
FAM175A
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
PARP1
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
TP53BP1
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11042216
11877378
17243194
18087291
19342239
20646866
9748285
|
UIMC1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17525341
17525342
17525340
17621610
|
BARD1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
99.0
|
1.0
|
Omnipath
|
16403807
16391231
28262780
15159397
25652403
26350354
26490435
14647430
11927591
25184681
16713569
11526114
35203293
9738006
12732733
24289923
11573085
18936166
23086937
24085845
12890688
15855157
24695549
19369211
9798686
11257228
11498787
12700228
11925436
10477523
19176389
23680151
25634209
23416467
34726323
29355525
18369654
14636569
11504724
12951069
19117993
20060929
17873885
14638690
18493658
11278247
15184379
22110403
11301010
11773071
12431996
10635334
20029420
9788437
17664283
21901007
25252691
12485996
10026184
12438698
17525341
16489000
8944023
15265711
12419249
20681793
9342365
27239795
20215511
25823446
19916563
|
BARD1
|
BRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCC3
|
FAM175A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCC3
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BARD1
|
BRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCC3
|
FAM175A
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCC3
|
UIMC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCC3
|
TP53BP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11042216
11877378
17243194
18087291
19342239
20646866
9748285
|
TP53BP1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
TP53BP1
|
FAM175A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11042216
11877378
17243194
18087291
19342239
20646866
9748285
|
TP53BP1
|
UIMC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11042216
11877378
17243194
18087291
19342239
20646866
9748285
|
TP53BP1
|
BARD1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11042216
11877378
17243194
18087291
19342239
20646866
9748285
|
BARD1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
FAM175A
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
FAM175A
|
UIMC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BARD1
|
UIMC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BARD1
|
FAM175A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BARD1
|
FAM175A
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|