COPS5
|
FOS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19180539
|
RHOA
|
OTUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20553488
7717051
|
OTUB1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19996094
|
PSEN1
|
EFHD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19012753
18996842
|
KLF8
|
BIK
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
2.0
|
0.8
|
ACSN
|
17671186
19798104
|
CIAO1
|
GOLM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
FOS
|
RHOA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10085083
15068801
|
CDC42
|
PARD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
10934474
|
FOS
|
EDN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21239258
1918021
|
FOS
|
EDN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9588211
16716598
|
FOS
|
CGA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15961508
|
PRKCZ
|
VHL
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5219754
17350623
|
PAK2
|
MYLK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
10748018
10092231
|
CFTR
|
CANX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12208510
5215704
|
F2RL1
|
CANX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
LTB4R2
|
CANX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
GRIA3
|
GRIA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0708699104
17989220
|
LTB4R2
|
DDOST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
HTR4
|
ADRB2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
5217738
15896782
|
BDKRB1
|
GRIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
DRD4
|
ADRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22723743
1001347
|
DRD4
|
ADRB1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
22723743
1001347
|
BDKRB1
|
INSIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
GNRHR
|
TIMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17201186
|
BDKRB2
|
AGTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
GRIK5
|
GOLM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
CTSG
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10978167
|
CTSG
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10978167
|
OTUB1
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
34591986
20622874
19996094
|
FPR2
|
CAMLG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
KLF8
|
CTBP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21416054
35140242
|
SFXN1
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
29568061
|
GRIA2
|
GRIA3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
14687553
17989220
|
GRIA3
|
GLRB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
VDAC1
|
SFXN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29568061
29128334
|
EDNRB
|
EDN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16713569
12972292
23597562
|
RHOC
|
RHOA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
31871319
33961781
31980649
|
KNG1
|
VHL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CANX
|
DDOST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.83
|
STRING
|
36370105
|
PSEN1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
EDN1
|
EDNRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16189514
10770212
16713569
7509919
23597562
|
CSH1
|
SGTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
KCNE5
|
SGTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
CGA
|
FSHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
CAMLG
|
GET3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HuRI
|
32296183
|
INSIG1
|
SCAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
TRAF6
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
GRK6
|
ADRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9819198
8672451
24561123
|
COPS5
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
GABRA1
|
GABRB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
GABRA1
|
GABRG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
COPS5
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16410250
|
PAK2
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
25416956
9535855
17353931
20696164
10320322
20936779
9822598
16204230
32707033
31871319
21311754
|
CDC42
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9574518
9305638
23109003
|
ZNF71
|
PRKCZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
AGT
|
CTSG
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6807977
9570564
20889553
|
CTSG
|
AGT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11747312
10899625
|
F2
|
F2RL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
873923
8615752
10079109
|
GLP2R
|
GCG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9990065
10322410
15471943
|
CGA
|
LHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11445554
18431515
10988300
|
GNRH1
|
GNRHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1333190
6090951
9419371
|
GNRH2
|
GNRHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1333190
6090951
9419371
|
COPS5
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
LEPR
|
LEP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
22405007
9786864
33961781
8608603
|
NMUR1
|
NMU
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
10899166
10894543
10811630
|
F2
|
F2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
CSH1
|
CSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
GRIA2
|
GRIA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
CDC42
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
GRIN1
|
GRIN2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
GRIN1
|
GRIN2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PRKCZ
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
14576165
|
GET3
|
CAMLG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
27458190
26675233
27226539
23041287
24392163
17382883
18477612
20375064
21444755
|
FOS
|
CRH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8793851
1663213
17895291
7894465
|
CRH
|
CRHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8536644
8243338
23504413
11123370
|
PENK
|
OPRD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9686407
15082510
|
GCG
|
GLP1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
18248821
11116211
15528268
7937318
8404634
|
CDC42
|
PRKCZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23109003
17353362
10733591
10873802
|
CDC42
|
PAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17145710
8107774
10559936
25416956
10320322
23331499
15020669
11340065
15003621
20936779
10934474
11413130
17353931
9535855
11950587
19628037
32296183
16204230
20696164
11248548
9822598
18719708
10613909
9823899
10461188
|
FOS
|
PENK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
1828294
7894225
7477937
2512642
9147818
7568884
8632147
8346209
|
PRKCZ
|
PARD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24152735
23109003
17353362
12390250
|
PAK2
|
MYLK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
2160950
18088087
10748018
|
AGT
|
MAS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
1282979212829790
12829792
|
AGT
|
AGTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12006574
21464395
10193788
10993080
16189514
15930094
9797979
16597412
17346243
|
GRK6
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9819198
24561123
|
F2
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9058715
10978167
15707890
10644723
14652070
11356985
23450633
18250335
12563219
22972936
|
F2
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10978167
1135698510978160
11356985
|
GRIN2B
|
GRIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12191494
19487695
15030493
8139656
|
GCG
|
GLP2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
24990862
11738243
9990065
|
INSIG1
|
SCAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12202038
12482938
23564452
12842885
32111832
26555173
32432943
|
CGA
|
FSHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15662415
2126341
12374801
30910395
|
LEP
|
LEPR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9463481
22405007
12226096
23331499
9207021
9218470
8608603
9786864
|
GRK6
|
BDKRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11517230
|
KNG1
|
BDKRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
18127230
3366244
8063797
1314587
|
KNG1
|
BDKRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
18127230
3366244
8063797
1314587
|
KNG1
|
BDKRB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
9313952
8856107
8735629
9111052
8063797
10422787
|
KNG1
|
BDKRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9203620
8063797
8302267
28966616
|
NMS
|
NMUR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
15635449
29288685
|
NMU
|
NMUR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
15331768
15292653
10899166
10811630
10894543
|
EDN1
|
EDNRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
1710450
1719979
8440682
2649896
|
EDN1
|
EDNRB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12972292
16597412
16713569
15629009
8440682
|
EDN3
|
EDNRB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
8460684
8086489
8904635
11982704
8001160
15629009
8440682
7524189
|
EDN1
|
EDNRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
90829707
6479761
9082970
7509919
16597412
16713569
23597562
15629009
8440682
7647976
10770212
|
EDN3
|
EDNRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
1710450
1719979
8440682
2649896
|
GRP
|
GRPR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
17251915
1720612
10454496
7838118
19463875
21729729
|
GNRH2
|
GNRHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17942747
17452338
19638591
|
GNRH1
|
GNRHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
26398856
414473
11726197
17452338
9414473
19640273
26774084
4930860
17095587
|
CORT
|
GHSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12161511
1122773711227730
11227737
|
APELA
|
APLNR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
29357134
25995451
25639753
29079036
28137936
26611206
28663440
24316148
|