Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
APOD CREB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CREB3 FXYD6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TLE1 FXYD6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GPR35 APH1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
FYN APH1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CYTH1 APH1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NCSTN APH1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18201567 6174903
APH1A CREB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
APH1A APP â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
APH1A APH1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 16252010 16630834
APH1A TRAF6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
APH1A NGFR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
APH1A NGF â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
YY1 APH1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21443683
HIF1A APH1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16645044
APH1B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APH1B NGFR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
APH1B NGF â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
APH1B PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12522139 12471034
APH1B TRAF6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
NGF APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
FYN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOTCH4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TMED10 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSENEN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP NGF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HIF1A BSG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020 22678117
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
TP63 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22777354 23837456
TMEM140 CREB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
FIS1 CREB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CREB3 PSENEN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PSEN1 CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10208590 11226248
CTNND1 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10208590 11226248
CYTH1 PSENEN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOTCH1 DLL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 20351093 22363487
PSEN1 DLL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 22330899 22363130
PSEN1 DLL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12794186
FYN PSENEN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HIF1A HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20010940 28602625
HES1 NOTCH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23037857 22172337
HES1 TLE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19250647 16608701
HES1 TLE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24270405 8687460
NOTCH1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18427106 0802047105
HIF1A NOTCH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18427106 0802047105
ITGB3BP KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSENEN NCSTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18201567 6174903
NCSTN PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10993067
NGF TRAF6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
NGFR TRAF6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
PSEN1 NOTCH1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 22330899 22363130
TP63 NOTCH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20442293 20950370
NOTCH1 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22330899 22363130
PSEN2 PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PSEN1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19012753 18996842
APP PSENEN â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
APH1B PSN2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12297508 15474363
CTNNB1 CTNND1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
PSEN1 TRAF6 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
TRAF6 PSN1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24399296 18996842 23707529 19012753
NCSTN PSEN2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HES1 TLE1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
PEN2 PSN2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12639958 16189514 22074918 15474363 12198112
FYN SDC3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9553134 16189514 16713569
PSN1 PSN2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12471034 15474363 21163940
FYN CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.87 0.87 Signor 12640114
NGFR TRAF6 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
APH1A PSN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12471034 12297508 15474363 16189514
NICA PSN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10993067 12297508 15474363
PEN2 NICA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18201567 22074918 16641999 14572442 18667537 12198112 15322109
CTNNB1 PSEN1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
APP NCSTN â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
APH1A PEN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26280335 22074918 14572442 12740439 17911105 15474363 19376115 18667537 16189514 15322109
APH1B PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12297508
APH1B NCSTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12857757 12297508
HIF1A BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020
NOTCH1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18722525 23331499 16256737
TMED10 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 16641999
PSEN2 PSENEN â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CDH1 CTNND1 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
TLE1 HES1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 33961781 19321451 18611861 19956621 8687460 24270405
PEN2 PSN1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 12639958 32296183 16189514 21115843 22074918 14572442 30559186 15474363 12198112 15322109
PSENEN PSEN1 â—¼   CLEAVAGE ✅ + 0.96 0.96 Signor 12522139
APH1A NICA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12857757 18201567 12471034 15257293 14572442 17911105 15474363 19376115 18667537 12297508 26280335
APH1A PSN1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 16189514 12471034 14572442 30559186 17911105 15474363 18667537 12297508 26280335
APP PSEN1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
PSEN1 PSENEN â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
APH1A PSEN1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
APH1A PSENEN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
APH1A NCSTN â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
NCSTN PSENEN â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
NCSTN PSEN1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
NICA PSN1 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 18201567 28351972 12603837 10993067 12471034 15257293 16641999 14572442 30559186 15890777 29611543 17911105 15474363 18667537 12297508
NCSTN APH1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 15189355 21071413 14572442 12471034 12857757 18201567 12297508
APH1A PSENEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12522139 15322109 12740439 16189514
APH1A PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12522139 12471034 16189514 12297508
APH1A PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12471034 16189514 12297508
PSEN1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10635315 11226248 16126725 11953314
CTNND1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 7542250 17261850 22752307 9535896 7651399 12707304 23180380 24424122 12640114 11226248 29207493 10225956 12427869 21670201 22850631 20371349 20940130 25468996 10409703 14610055 7876318 22715382 10629228 19711372 8660921 10931041
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
PSEN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 17145710 11168528 16126725 11226248 2195779 11161700 12070348 9738936 10037471 18070361 9632714 10092585 9223106 12297048 16306047 10341227 9852041
FYN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 20026641 22264731 24511551 25241761 22340496 12640114 25803041 26509276
FYN CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 26477567 11777936 17194753
DLL1 NOTCH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 21685328 11006133 12482954 22353464
DLL1 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 29910816 22353464
DLL1 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17537801 11006133 9819428 21685328 1006133 16140393 98194281 22353464
DLL1 NOTCH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21685328 10958687 22353464 23111325 9244302
NOTCH1 HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10520600 11120788 10066785 16869730 12814948 7566092 21956839 9819428 10933396 11866432 20007915 10205173 11741889 19165418 15546612
NOTCH1 HES1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23343194 19000719 18495817 16039586 19619488 17143292
NCSTN PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 12603837 23331499 21071413 14572442 12471034 10993067 18201567 18988627 12032140
NGF NGFR â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 10764727 11729324 16893414 2172988 1372492 24224055 14985763 22227462 11114882 15258592 14699954 3037029 1714587 9775403
NOTCH1 PSEN2 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 10879540 10206645 12209127 9620803 19151708
NOTCH1 PSEN1 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 10879540 10206645 12209127 9620803 19151708
PSEN1 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10593990 10077672 16713569 10206645 12374741
YY1 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16713569 12913000
PSEN2 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11518718
PSEN1 NOTCH2 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 24842903 10206645 12209127 9620803 11518718
PSEN2 NOTCH2 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 24842903 10206645 12209127 9620803 11518718
PSEN1 NOTCH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11518718
PSEN2 NOTCH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11518718
PSEN2 NOTCH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11518718
PSEN1 NOTCH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11518718
PSEN2 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11518718
PSEN1 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11518718
PSENEN PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12522139 12198112 15322109 16189514 21115843 12639958