Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CASP8 CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18669646 0712034105
CASP6 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 NUCB2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 6175494 18154733
CASP3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17899380
CASP8 NUCB2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 6175494 18154733
CASP6 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
NUCB2 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 6175494 18154733
NUCB2 CASP6 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 6175494 18154733
JUNB NUCB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NUCB2 CALU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26344197
TNNI2 NUCB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
Z280A NUCB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
COL10 NUCB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CASP8 CASP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15254227 11832478 18669646 11437602 8962078
CASP6 CASP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 8900201 25241761 18723680
JUNB BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16713569 25184681 12080089 33961781 18259752
CASP3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12149654
BRCA1 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17428466 11777930 10962562 18025037 18350249 12647291
BRCA1 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 12771027 9346961 10779360 11877377 10367887 19004803 21060331 12496474 19793801 15650754 10962562 21337561 9892649 10528224 15459660 20029420
CASP8 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 15755874 17179148 9501089 9950028 18669646 23308069 10988287 18458084 16964285 9885230 9765224 11437602 15014070 21295084 8962078 9208847
CASP3 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25241761 17899380 8900201 9922454 18723680
CASP8 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18073771 9545235 10872455 18329793 9727491 9463409
CASP8 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18329793 12232792 9727491