Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRB2 ACTR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
AP2S1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2M1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
ITCH CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12226085 5215735
CBL ASAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
CBL SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219404 17141222
CBL FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBL SH3GL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11894095 16713569
CBL FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBL FGFR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
EGFR HRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR GRK2 â—¼   COLOCALIZATION 2.0 0.8 intact 5217433 15620700
EPN1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19054389
EGFR HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
EGFR ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24797263 20029029
EGFR ABCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12196520
ASAP2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PPP2R1A GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
APP GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12485888 5215996
GRB2 CYTH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB2 HOXC8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 PLD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731738 16407827
GRB2 ACTR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ARPC1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ARPC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ARPC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 HSPA1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 BIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15834155 5217666
GRB2 CAPZB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 IL2RG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ARPC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ARPC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 AP2S1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ACAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 CBLB â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
IL2RB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10602027
VPS37C HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23208550 8428323
HGS VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS VPS28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23208550 8428323
HGS VPS37D â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
MDM2 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214648 11588219
ARRB2 MDM2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5214648 11588219
HSPA8 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA1L TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF6 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0906941106 19955404
PLD1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SRC HOXC8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CETP ARPC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ARAP1 ARPC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ARPC3 ARPC1B â—¼   PROXIMITY 2.0 0.8 intact 20404198 0911668107
LDLRAP1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VPS37C SNF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21757351 15218037
VPS37C STAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
PPP2CA CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11278485
ACTR3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EEA1 IGF2R â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
ARF1 GBF1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8810314 9614177
ARFGEF2 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8945478 8945477
SMURF2 TGFBR1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 14722617 15265520
WWP1 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15221015
TGFBR1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 19114990
HRAS VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12695509 5216326
HRAS CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621645 5220985
HRAS CHMP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS EGF â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
IL2RA IL2RG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RA IL2RB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
AP2B1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
CD36 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ACAP1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC GIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 12695502
SRC ASAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
SRC ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16432186 0510562103
SRC CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17094785 7033811
PDCD6IP SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217348 15557335
CDC42 KIF5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
CDC42 KLC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
CDC42 RAB35 â—¼   COLOCALIZATION 2.0 0.8 intact 19289122 7012064
CDC42 PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10934474
CBLB ASAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
CBLB ASAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
CBLB FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB FGFR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
ITCH CBLC â—¼   COLOCALIZATION 2.0 0.8 intact 12226085 5215735
CBLC FGFR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CAV1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMURF2 FHL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18157088 6492033
SMURF2 DAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
EGF EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24269888 25728925
GRK5 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24632620
ARAP1 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FGFR3 CHMP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DNM2 SH3GL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10542231 5211933
ITCH SH3GL2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5216835 14684745
SH3GL2 ITCH â—¼   COLOCALIZATION 2.0 0.8 intact 5216835 14684745
PRKCZ PARD6G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
DAB2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRK2 GIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18369319 6608764
GRK2 GIT1 â—¼   COLOCALIZATION 2.0 0.8 intact 18369319 6608764
GRK6 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA8 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRK2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2CA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SCARB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ARF3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP PLD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP SNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ARFGEF2 ARFGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19332778 0901558106
BIN1 AMPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21779028 11231140
SH3GL1 DNM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10542231 5211933
EPS15 EPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6179743 18200045
EPS15L1 EPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9723620
VPS37D STAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
VPS37A STAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM VPS28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
CHMP3 STAMBP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SNX32 SNX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PDCD6IP CHMP4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0707601105 18434552
GRK2 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10085131
VPS4A PDCD6IP â—¼   COLOCALIZATION 2.0 0.8 intact 17853893 6169256
VPS37A SNF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21757351 15218037
VPS37D SNF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21757351 15218037
CAPZB CAPZA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ABCG8 ABCG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16870176 5218866
VDAC3 VDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CAV2 EGFR â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CHMP4A CHMP5 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNM2 DNM3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
ARPC5 ARPC1B â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 24981860
KIF5A KIF5C â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
CHMP1A CHMP5 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
ITCH TRAF6 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
DNAJC6 HSPA8 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
ARPC1A ACTR2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
AMPH AP2M1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EGFR APOB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28065597 24189400
EGFR IGF1R â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
EGFR FHL2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29321665 15657067
ACAP1 GRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17474147 25814554
GRB2 VPS28 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARRB1 HGS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23208550 20505072
HGS ARRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23208550 20505072
ARRB1 TRAF6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16378096 19879840
RAB5C ARF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26344197
ARF1 ARF5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
DAB2 AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22323290 34079125
AMPH AP2S1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VDAC3 SRC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CAV3 CAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARRB1 ITCH â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17947233 18544533
ARRB2 AP2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32962859 17620599
VDAC3 APOE â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EEA1 RAB5B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12493736 10491193
CHMP5 CHMP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ASAP3 ASAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ASAP3 ASAP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EHD1 EHD3 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
ACTR3C ARPC1B â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
ARF6 CYTH3 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
ARF1 IQSEC1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
ARF1 IQSEC2 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
CXCR4 ITCH â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
DNM2 SH3GL2 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CBL ITCH â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12226085 19341794
EGFR AP2S1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24797263 25754235 24189400
GRB2 DNM1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217666 15834155
GRB2 WIPF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 31980649 21706016
ARRB2 TRAF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19955404 16378096 25425640
CHMP6 SNF8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14505570 16371348 33961781
CXCR2 ARRB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 11170396
AP2A2 DAB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22323290 11247302
ARRB2 SRC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19202075 19122674 11877451 23242524
ARRB1 IGF1R â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33158816 15878855 21685939
AP2A1 AMPH â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 12057195 33961781
EPN3 EPN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ARRB2 CLTC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AP2B1 CLTC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
SRC CBL â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6538879 18273061
SRC CBL â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 5219404 17141222
SNX2 EGFR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24797263 9819414
ARPC4 ARPC1B â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
ARRB1 SRC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33844281 19202075 16432186 23242524
CDC42 CAPZB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31478661 31980649
RAB5A RUFY1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 14617813
SNX1 VPS29 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11102511 26344197
EPN1 EPN3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 21115825 33961781 26186194
APOA1 APOB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28183703 7592581 19164805
ARRB2 SRC â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
DNM1 DNM3 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CHMP4A VPS4A â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CHMP1A CHMP4B â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
EHD2 AP2M1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16713569 15182197
EGFR AP2B1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24797263 24189400 7534311 23956138
EGFR AP2A2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24797263 8548289 24189400 23956138 31959764
IL2RB GRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 10602027
SRC GRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 11964172 9016807 12624098
ARF6 ARRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11533043 16189514 11867621
APOA1 APOA2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10722751 24981860 3104518
EHD1 EHD4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22863883 30833792 22939629
ARF1 ASAP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16223492 16332543
AP2A2 BIN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9195986 10430869 9182529
CBLC ITCH â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12226085
SNX2 VPS29 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11102511 22863883 22939629 26344197
CHMP2A CHMP5 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CHMP2B CHMP4B â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
ARF6 CYTH2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
CHMP4B VPS4A â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
ARFGAP1 ARF1 â—¼   GTPASE_REACTION ✅ + 0.85 0.85 Signor 10102276
SNX1 EGFR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9819414 8638121
FGFR3 GRB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9045692 26344197
TRAF6 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10635328 16189514 22447928 29545793
PLD1 ARF6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 12379803
APOA1 APOC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15174051 11991719
CHMP2A VPS4A â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
PLD2 ARF1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12519790 10801846 11373276
ASAP2 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10022920 17474147
RAB5C CAV1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
ITCH BIN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26613292 28235806
AP2A2 EPN1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
ACAP2 RAB35 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CDC42 PARD6G â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
PDCD6IP SH3GL1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
EPS15 AP2M1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24189400 33961781 26186194 19380743
EGFR ARRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
GRB2 ARAP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31980649 21706016 33961781 19380743
GRB2 GIT1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21900206 31980649 21706016
TRAF6 FHL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16184196 18768464
PLD1 ARF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9688545 26344197
EPS15 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 19380743
AP2A1 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 26344197
EPS15 AP2S1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 19380743
PLD2 CAV1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14675200 10675563
RAB5A VPS45 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 11062261 29568061 15016378
VDAC2 VDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31536960 22939629 30021884
CLTC HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AMPH AP2A2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ARF1 ARFGAP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
APOE APP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
SH3GL1 SH3GL2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
GRB2 STAMBP â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
APOA1 LCAT â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ARRB1 MDM2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
AP2B1 ARRB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PARD3 PARD6G â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CLTB CLTC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
EGFR HSPA8 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR PDCD6IP â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR SH3GL2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CLTB CLTCL1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR AP2A1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24797263 20029029 24189400 23956138 25754235 7534311 31959764
EPS15 GRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17474147 19109251 7797522
DAB2 GRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11371563 16713569 17474147 9569023 10542228 20936779 22323290
IL2RB HGS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21362618 18445679
IGF1R MDM2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 12821780 20195357 28092675 18632619 19165858
PLD1 CDC42 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 10747870
PLTP APOA2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 9469594
ARF1 ARF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
SMURF1 SMURF2 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
IL2RG IL2RB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11886175 10903799 8006584 20816854
AP2A2 AP2B1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12086608 16189514 33961781 34079125 26344197
FGFR2 FGFR3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 23972473 33961781
ARRB2 ITCH â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17947233 18544533
SNX2 SNX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 11102511 9819414 33961781
IST1 VPS4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
LDLR APOB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24447298 12031600
APOA1 PLTP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11854286 9469594
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
IGF1R MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EGFR EPS15 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CYTH2 ARF6 â—¼   GTPASE_REACTION ✅ + 0.88 0.88 Signor 14565977
CHMP6 SNF8 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
STAM STAMBP â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ARRB2 MDM2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CHMP1B STAMBP â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CHMP2A CHMP2B â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
ACTR3B ARPC5L â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
EPS15 HGS â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
AP2A1 AP2B1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EGFR AP2M1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24797263 20029029 31980649 24189400 23956138 24067654 25754235 31959764
AP2M1 AP2S1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 EPN1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
CBLB EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24797263 11375397 20308550 19531499 33848699 10635327 30515972 18271526 28572092 10086340 16729043 31959764 16702950 15657067
EGFR ARF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 24797263 20029029 31980649
EGFR LRP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649 28065597
EGFR HGS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23477725 12953068 20308550 23153581 23602387 25588945 18508924 15212941
EGFR ARRB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
FGFR2 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24440983 22726438
GRB2 ASAP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17474147 21706016 33961781 20936779
HGS SNX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 19874558 11110793
ARF6 ARRB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11533043 16189514 11867621
AMPH AP2B1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 10748223 33961781
AP2S1 AP2B1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 12086608 16189514 33961781 34079125 26344197
CBLC SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20525694 14661060 22888118 9988270
DAB2 SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12473651 16189514 16713569
SRC CAV1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8910575 8632005 8621645 29720121
EPS15 AP2A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10764745 19380743 10953014 8662627 9049247
LDLR APOE â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24447298 12036962 20030366
APOA1 ABCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12084722 30458687 27017521
CHMP1B CHMP3 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
LDLRAP1 NOTO â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CHMP1A STAMBP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
LDLRAP1 MAGEA4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
SMURF2 TGFBR1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
AMPH DNM1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
FGFR2 GRB2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
DNAJC6 HSPA8 â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 24789820
CHMP4C PDCD6IP â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
CAV1 CAV2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ARRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
AP2B1 AP2M1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12086608 16189514 16713569 24189400 33961781 19380743 26186194 30021884 34079125 26344197
CBL PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
CBL PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
EGFR CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27059931 7657591 8665853 27903975 15107835 24797263 28791635 9756944 23799367 23175185 28198003 12734385 14505571 20940296 19155296 10635327 15117950 22833562 29629558 12061819 8662998 10086340 33762435 11994282 20877636 32714745 25005938 31182136 19578043 7782294 24714105 10799548 23158001 26055326 33617900 23153581 15210722 25872741 15657067 19947936 10428778 18508924 16969069 17971399 15962011 19531499 25521828 23774213 22976291 31959764 22591401 18255265 15735736 16713569 20562913 17880946 16914641 9890970 22394513 16729043 32114396 17995934 17182860 18319245 18271526 17545148 15383614 25140053 32377695 15465819 33627783 8798643 25754235 15282549 26177020 22266821 16923119 17242169 30544639 12604776 11239464 9130710 19225046 11370743 21772844 16105874 18273061 7592693 23897813 17486068 16246327 23457600 32904620 12803489 31120930 15668240 22203672 23418353 20124286 28541302 33323455 10092522 14627991 15677445 15159412 20308550 16849543 12593795 19836242 9121472 19713535 18316398 11408594
SRC CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29899407 17094785 16713569 18273061 7782294 12941616 10829062 31120930 15135048 17141222 18996392 8635998 11994282 22203672 19861161 16636290
CBL IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18632619 17635922 10514377
SRC EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17284441 6169640
CBLC EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22888118 29945960 10571044 10362357 31959764
EGFR CAV2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 15273741 25402006 16799092
EGFR CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16407214 19446582 22411794 31980649 12388423 24658140 15273741 25402006 16799092 9374534 34079125 12354760 10781609 15657067
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GRB2 ASAP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31980649 21988832 17474147 21706016 33961781 20936779 19380743
HLA-C GRB2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
AP2S1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12577067
EPS15 HGS â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 12551915 27008177 18362181 10809762 10514494 15772161
LRP1 APOE â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 2779654 11421580 20030366 15182176
MDM2 ARRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17984062 15878855 32450252 26545496 12488444 11588219 21988832 21466165 33649538 21389118 18544533 21081496 32828283 12538596
PPP2CA MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983168
FHL2 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18768464 16184196
ARF6 PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30944160 12379803
ARF1 PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16054594 9688545
CYTH1 ARF6 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10652308 11050434 1511013
ASAP2 ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10022920 10749932
CYTH3 ARF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18451304 9707577 10652516
ARF1 CYTH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18451304 9707577 10652516
ARF1 CYTH4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18451304 9707577 10652516
ASAP1 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11773070 16223492
CYTH1 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9756891 9653114 10212218
TGFBR1 SMURF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15496141 11163210 11278251
TGFBR1 NEDD4L â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15496141 11163210 11278251
AP2A2 ARRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
ARRB2 AP2B1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21118812 17620599 12070169 10097102
ARRB2 AP2S1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
ASAP1 SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17474147 9819391 16636290
SRC PPP2R1A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
SRC PPP2CA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
CAV2 CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12414992 16189514 31980649 9361015 18081315 33961781 24013648 10212252
CCR5 CXCR4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12429730 15660419 18632580
CXCR4 ITCH â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19116316 34927784 24489825 28264927 22275353
DNM2 DNM1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GIT2 GIT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12473661 28514442 16628223 33961781
KLC1 KIF5A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 3130248 1607388 3134048
ASAP2 ARF5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10022920 10749932
ARF4 GBF1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17956946 22389062 23567335
EEA1 RAB5A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11493665 16902405 15016378 11870209 10720461 34079125 11718716 9697774 10491193 14600265 20534488 15328530
EEA1 RAB5C â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12493736 25266290 34079125 25114243
ARRB2 ARRB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24069330 17353931 33961781 17620599
STAM ASAP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 0509166103 7102318 16636290
ASAP1 SH3GL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 0509166103 7102318 16636290
PCSK9 LDLR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18250299 22081141 25613181 18753623 17435765 23085658
ABCG8 ABCG5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12208867 16870176 27144356
LCAT APOA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 4335615 15654758 16189514 1644835 10026251 10222237 1587806 17676061 3104518
VPS4A CHMP2A â—¼   CLEAVAGE ✅ + 0.9 0.9 Signor 30989108
SNX1 VPS26B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
AP2A1 EPS15 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SNX2 VPS26B â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
AP2A2 EPS15 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
DNM2 GRB2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CLTA CLTCL1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
SNX1 SNX32 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CHMP4A PDCD6IP â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
EPN1 EPS15 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
DNM1 GRB2 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
ACTR3B ARPC5 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
CHMP4B CHMP5 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
VPS28 VPS37A â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
LDLRAP1 STN1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
DNM1 SH3GL2 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
ARFGAP1 ARFGAP3 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ARFGAP1 ARFGAP2 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
AP2B1 EPN1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 34079125 22863883
CHMP1B VPS4A â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CHMP1B CHMP5 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
AP2B1 LDLRAP1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CBL SRC â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CLTCL1 DNAJC6 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CHMP1A CHMP2A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CHMP1B CHMP4B â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
IL2RB IL2RG â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
SNX32 SNX1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 32296183 25416956 33961781 21516116
SNX32 SNX2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 32296183 33961781
SNX1 VPS29 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PARD6G PRKCZ â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
KIF5A KLC1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
HOXC8 LDLRAP1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
CHMP4B CHMP6 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CHMP6 VPS4A â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
KIF5C KLC1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
KIF5B KLC1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
EGFR EPS15 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32377695 15701692 16499958 21226813 19109251 10953014 9049247 16429130
SNX4 BIN1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 31413325 12668730
ACTR3B ARPC2 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
CBLC SRC â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CBLB EGFR â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CAPZA1 CAPZA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
GRB2 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5220480 7642581
EGFR CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16729043 5218694
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
CBLB GRB2 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
MDM2 ARRB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15878855 11588219 21466165 21857681 18544533 21081496 29676828 12538596 19879840
AP2S1 AP2A1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 31353312 16189514 7593184 33961781 26344197
BIN1 AMPH â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 9348539 9315708 33961781 31413325
RAB5C RAB5A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 17353931 26496610 33961781 34079125
ACTR3B ARPC1A â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
ABCG5 ABCG8 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CLTC DNAJC6 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
ACTR3B ARPC3 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ACTR2 ACTR3B â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ACTR3B ARPC4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
AP2A1 AP2M1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
EGFR EGF â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8145580 21439278
SRC EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 8845374 21573184 25402006 7506422 10075741 19704002 10971656 23175185 10777553 22227249 20935677 20624308 21268077 17158602 24189400 9020193 16713569 22973453 11983694 24658140 28065597 21278788 17284441 7797556 20333651 7527393 10358079
EGFR EGF â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16274239 25241761 10085134 11684674 28988771 22729867 18271526 30083275 10788520 23597562 19531499 26280537 8663535 25453753 21822280 12297050 2790960 21439278 12093292 12620237 10970856 18427122 25080504 17697999 9135143 15620700
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
ARPC4 ARPC3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 23148219 11162547 22863883 33961781 24981860 22939629 26344197
ARPC3 ARPC5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 23148219 26655834 22863883 33961781 24981860 26186194 22939629 26344197
EHD3 EHD1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 33961781 26226295 16251358 12121420
AP2S1 AP2A2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 26344197
EPN1 AP2A2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12057195 9723620
EPS15 EPN1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15809337 9723620 10791968 18200045 18375383 21115825 16429130
CHMP4B PDCD6IP â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
CHMP2A CHMP3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ARPC1A ARPC5L â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CHMP3 CHMP4B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CAPZA2 CAPZB â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
LDLR PCSK9 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SNX2 VPS29 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
EEA1 RAB5A â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CHMP3 STAMBP â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
VPS26B VPS29 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ACTR3B ARPC1B â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ARF1 CYTH2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ARRB1 CLTC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RAB5A RABEP1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
ARPC2 ARPC5 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 11805826 26655834 22863883 24981860 22939629 26344197
ARPC2 ARPC4 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 11805826 11162547 22863883 33961781 24981860 22939629 26344197
KIF5C KLC1 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 10491391 33961781 9624122 26344197
KLC1 KIF5A â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 10491391 33961781 9624122 22939629 26344197
CHMP2A CHMP4B â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CBLC EGFR â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
AP2A2 AP2B1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EGF EGFR â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CHMP1A IST1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CLTA CLTC â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CHMP1A VPS4A â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CBLB GRB2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21900206 28514442 16189514 25416956 31980649 12577067 31467278 26264872 10022120 9614102 29997244 21706016 32814053 33961781 20936779 10086340 27107012
ARPC2 ARPC3 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 11805826 23148219 22863883 33961781 24981860 9230079 26186194 22939629 26344197
ARPC4 ARPC5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 12451597 11162547 26655834 22863883 33961781 24981860 22939629 26344197
EPS15 AP2A2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 26822536 18362181 10809762 19380743 8662627 9049247
AP2A2 AMPH â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 9280305 9195986 33961781 8552632 10748223
ACTR3 ARPC5L â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
AP2B1 AP2S1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CAPZA1 CAPZB â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
AP2A2 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2B1 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CHMP1B IST1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ACTR3 ARPC1A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ACTR2 ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AP2M1 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC1B ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC2 ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AP2A2 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC1A ARPC5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ACTR2 ARPC1A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
HGS STAM â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC1A ARPC3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC4 ARPC5L â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC1A ARPC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC1A ARPC4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC3 ARPC5L â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ACTR3 ARPC1B â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ACTR2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC1B â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ACTR2 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
CLTCL1 AP2M1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
CLTB AP2M1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
HGS CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
EGF CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
CBL STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 CBL â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 31980649 8649804 8995445 25036637 23799367 11997436 8943292 9242692 10570290 8662998 11399323 10086340 7642581 9108392 20936779 11133830 8626404 17094785 8063801 9129019 8900205 15210722 8621483 25872741 25814554 9178909 16906159 8950973 17971399 10025673 9295052 19380743 9716598 16713569 11964172 9234717 8083187 7537740 8824292 9259313 9311917 7791764 17072306 14725908 33627783 9461587 9434624 9851874 8695851 12839496 17944804 11792427 10204582 8621719 11823423 9541596 33961781 169092 11263968 98621719 28514442 18273061 7592693 9174058 21706016 8995358 9872323 9233773 9367879 7544353 12941616 10829062 20124286 917890 15677445 9092538 10521482 8647120 19836242
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
SRC CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 9525940 7782294 16713569 18273061 10829062 10799548 10934191 12604776 9890970 17570479 9013636 15135048 17094785 25784557 8635998 10092522 12522270 8621719 17141222 16636290 11239464 19861161 11994282 12941616 14739300 22203672 8849724 15212693
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
PPP2CA CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11390642 17015476
DNM2 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 CLTC â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
SRC CLTC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10089883 19289168 12237126
EGF EGFR â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 15003992 15175028 15466195 15958574 18423981 19631971 20430953 21098712 8101258
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
PPP2CA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
CBLB EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17145710 19531499 11375397 10086340 12577067 10542134 17635922 10514377
PDCD6IP EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 31980649 15456872 12771190 24658140 15557335 25402006
EGF EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 131.0 1.0 Omnipath 17145710 17081983 21822280 20813200 23613900 9135143 25453753 21303971 10209155 26821125 12297050 27387652 25241761 30083275 12093292 30197274 21649524 19531499 18762250 16729043 26921391 17697999 17575160 21722395 12620237 19129184 10788520 23331499 3494473 15620700 14568001 15958209 24096486 18253097 16843263 18320059 21532939 10085134 22260327 15708576 26280537 23912460 21858221 11116185 10970856 27462018 18427122 25080504 20953304 19135477 11684674 8639530 27564112 18270696 2790960 17971399 23185569 19895983 28988771 29617357 23597562 19531623 23950932 21071413 8663535 6289330 16274239 17563729 21439278 20458382 22216880 18271526 12771140 21311755 24709886 25366117 12648462 21107857
CBLC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10362357 22888118 17635922 10514377
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 17389395 10953014 24269888 19534553 25260758 19583965 19690332 15951569 9049247 17016520
EGFR PLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9837959 20647543 20176813
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
EGFR ARF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12446727
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
WIPF3 GRB2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11340081 11829459 10878810 12213210 11553796 10781580 11157975
HGS GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
FGFR4 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
GRB2 STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
FGFR2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22726438 19735729 26103942 20554525 23420874
CBLB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 10022120 25416956 21706016 31467278 32814053 9614102 17635922 11375397 8626404 16189514 21900206 20936779 27107012 12577067 10514377 19531499 10086340 29997244
EGF GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17081983 19531499 17673906 10973965
EPS15 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7797522 17474147 19109251
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
AP2A1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12577067
GRB2 DNM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 8402898 9009162 10206341 11877424 17244534 7505438 19380743 21706016 16713569 15834155 9452513 17474147 8119878
GRB2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17496910 16713569 17673906 11352655
HGS SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HGS CHMP2A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20708039 11333915 16867982 9733768
SRC LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12789267 11854294 18381291 21650223
ARRB1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15878855 23331499 21081496 12538596 17303558 11588219 21466165 18544533 21857681 19879840
MDM2 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 25241761 28092675 12821780 18632619 17303558 19165858 36042202 20195357
CD36 TRAF6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 18070982 15247281 21220427 12140561 12138165 8837778 19592497 18347055
TGFBR1 TRAF6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 24132110 24336330 7594497 9865696
TGFBR1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 18922473 22710166 23331499 19010789 16474430 22943793 17934056 20519943 12809600 21900405 11133108 18758450 14557817 15548370 19920116
CYTH2 ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9417041 16189514 14565977
ARPC1B ARPC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
VPS4A CHMP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14505570 30989108 16730941
VPS37C VPS28 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
ACTR3 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC1B ARPC2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC1B ARPC4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC4 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC4 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ASAP2 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10022920 11304556 10749932
ARFGAP1 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 1010276 10102276 19020038 16189514 9733781
CYTH2 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 14654833 17563369 8945478 16189514 10198630 9417041
ARF1 PLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10801846 11373276 12519790
SMURF1 TGFBR1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 14657501 14722617 14744429 15265520 15761148 21572392 22949611
TGFBR1 EGF â—¼   ENZYMATIC_REACTION ✅ 41.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16424049 16474430 16572188 17070508 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
CAV1 TGFBR1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
SMURF1 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 9335505 21897371 9335507 17317136 22949611 12151385 12857866 23331499 22921829 11278251 21572392 14657019 12519765 15761153 11163210 15221015 15761148 22286770 9215638
DAB2 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 16713569 11387212
SMURF2 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11278251 15221015 22921829 22624557 9335505 21897371 22286770 14722617 9335507 17317136 15761153 12151385 11163210 9215638
HRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
HRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
SRC HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12695509 9626657 9020108 25157176 33413561
IL2RG IL2RB â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
IL2RG IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL2RB â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
IL2RB IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 8568232 15265897 7514277 10903799 11886175 8026467 15933202 7681595 15178252 1545122 8260650 16189514 11851401 8006584
IL2RA IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15933202 15265897 8568232 8260650
IL2RG IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 8568232 15265897 7514277 10903799 11886175 8026467 15933202 7681595 15178252 1545122 8260650 16189514 11851401 8006584
IL2RB IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8568232 15265897 11886175 15933202 15178252 1545122 8260650 3116143 8006584
AP2A2 CLTCL1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AP2A2 CLTB â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
CLTCL1 AP2B1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
SRC AP2B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18938240 15592455 17456551 18083107
CLTCL1 AP2S1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
SRC CDC42 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
CAV1 SRC â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
PRKCZ SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17496910 11940581 21386996 10527887 11447289 19615955 16488589 6321473 8321321 12845332 11313945 16189514 12040186 19568798 15567848 14585353
EGF SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23349873 19481075 15845350 22927910 27462789
SRC CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14506284 26816343 9626657
SRC ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17456469 17456551 16432186
SRC PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 25003662 10978272 21292165 23796501 24676687 22771321 24395787 17635907 26378614 16286244 27013170 23222956 25726524 24997451 31992581 12921784 1325671 17303700 23251465 20558158 21554241 23926298 25931585 22299660 18208556 21791414 23436320 32130916 17394530
SRC DNM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 7505438 12011079 9880482 11956154 15834155 19380485 9539797
SRC PDCD6IP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15557335
SRC CAV2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 23826261 15212693 15504032 20455999 17081983 12091389 20068231 22819829 18081315 18669648
SRC GRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12624098 16725308 11278940 11566877 16189514
SRC SH3GL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23255596 16054026
SRC CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 20201820 23469926 24755228 24525631 15592455 27259249 17979878 19409422 11075810 17389395 14992595 18578522 11094059 11451957 24244013 8632005 24131997 12921535 21324536 16332692 8621645 18815812 27170175 17517963 12531427 24632723 23091071 19625610 18789131 24502576 17016520 20107068 21382479 24364863 25937636 19604397 23280667 16713182 22596063 26169283 8910575 17190831 18707149 25097454 12036959 18176934 15212693 18400052
SRC IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17389395 15212693 18691976 7559478 7493944 7537849 20068231 23472139 8550552 17016520 8940173 9480911
SRC ASAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9819391 16636290 24957964 17474147
SRC CBLC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9988270 20525694 24425877 14661060 22888118
SRC GIT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14523024 24699139 22302306 20689073 17570479
WIPF3 CDC42 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11340081 11829459 10878810 12213210 11553796 10781580 11157975
CDC42 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16714282 7512369 9113980 23434736 11306516
CDC42 PARD6G â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 11260256 14676191
CDC42 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 17353362 10733591 10873802
ITCH CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28264927 19116316 24489825
GRK6 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 30936203 25355818 20048153 24309376 19116316 28328745 24489825
GRK3 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11668182 16189514
CLTA DNM2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA DNM2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
ITCH SH3GL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14684745 17038327 26613292
PRKCZ PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24152735 23109003 17353362 12390250
AP2A1 CLTB â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AP2A1 CLTCL1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
APOE APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9202294 10559559 10428074 10842709 17116874
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
PPP2CA ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
APOE LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12036960 24447298 31677479 20030366 12036962 15840700 11327878
CLTB HSPA8 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9100026 6146630 17978091 26042225 20033059
HSPA8 CLTCL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9100026 6146630 17978091 26042225 20033059
ARF4 ASAP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 23945166 9819391 19153612 18685082 22983554 16431365 16038802 16136078 23567335
ARF4 GBF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 22013193 20357002 17429068 18524849 16030262 16633337
EPS15 SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
EPS15 EPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 16429130 18375383 35044719 9723620 10393179 18200045 15809337 21115825 10791968
RABEP1 RAB5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15328530 17145710 10720461 11452015 11718716 8521472 26430212 9524117 15378032 9045618
RAB5A EEA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 15328530 17145710 20534488 14600265 11718716 10491193 11493665 11870209 16902405 15016378 10720461 9697774
RAB5C EEA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25266290 12493736 25114243
STAM SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
CHMP1A VPS4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17928862 16730941 23045692 14505570 11559748
RAB8A ASAP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 20308558 22433857 22983554 12221131 23567335 21273506
VPS37D VPS28 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37A VPS28 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
ARPC1B ARPC5 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GRK3 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 25923671 12403770 12065593 10085131 11782464 18753410 21148810
PCSK9 LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22081141 29209441 17435765 25613181 23085658 18753623 18250299
APOB LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12031600 24447298 11986215 15840700 1132787812031600 11327878
APOA1 ABCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 30458687 12084722 12869555 22271762 27100352
APOA1 LCAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 1587806 10222237 10026251 19860440 16189514 15654758 4335615 17676061 1644835