Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17015431
PLK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 7266226 19833129
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
DDB1 MUS81 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 27354282 24412650
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
UBXN7 CUL4B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22466964 31973889 18775313
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
COPS6 DDB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
LATS2 LATS1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 24255178 21233212 32707033 34079125
UBXN7 NEDD8 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22466964 24076655 22537386
CUL4B DDA1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
NEDD8 CUL4B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 10597293 18274552 21145461 16503656 23201271 31973889 16620772
ERCC4 MUS81 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
COPS5 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
DDA1 CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21145461 26496610 16949367 19295130 31973889
DDB1 DDA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17609381 16964240 20562859 26344197 16949367 17452440 19295130
COPS5 DDB1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
SLX4 EME1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31495888 32398829 19595721 19596236 19596235
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
ERCC1 MUS81 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
NEDD8 CUL5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18805092 24654937 33961781 18274552 10597293 21119685 21145461 23201271 24076655 18247557 28522566 22405651 31253590 28514442 20847044
TP53 DDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16357511 19382146
SLX4 ERCC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22902628 23093618 23623386 31495888 25538220 32398829 23033263 21240275 26186194 19595721 19596236 28514442 19596235
ERCC4 SLX4 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
NF2 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26045165 24012335
NF2 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26045165 24012335
SLX4 MUS81 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23033263 29850896 21240275 21516116 25533185 23994477 22902628 31495888 19596235 32296183 23093618 32398829 19596236 28514442 25416956 29892012 23623386 19595721 24012755 25224045
SLX4 PLK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25852190 22902628 31495888 25659891 32707033 19596235
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ERCC1 SLX4 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
MUS81 SLX4 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
LATS2 NF2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
DDA1 DDB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ERCC1 ERCC4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
DYRK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 29296831 21383696 14749479 11740489 20171273 25778922 15843377 33906076 10581258 15750624 15897882 15706352 26236013 24899407 33572115 17906639 20935676 24379358 17386256 15870257 26346493 12427754 34103685 17567906 11101524 17210684 18536714 15381073 19965871 26578795 26087959 28060750 21765464 20673369 34216619 16601678 17380123 33443163 18216278 21642861 15526030 22878263 17349959 16738336 20696760 19882354 16219768 17105820 16793543 17332358 24901999 16247456 24196445 26804244 15657359 27208501 18056705 21765463 23420876 22797063 16377624 19861417 18160537 12676607 20123963 15489221 17591690 20514025 23149944 19857493 17891183 27034505 11780126 21057547 25944899 26341817 17349958 20962272 22525275 19828042 12902982 19465479 15471885 15322239 11495913 12907596 32083004 25915850 20018442 24145406 26029824 21394211 12093737 33872315 20610713 20024960 26113041 20811699 18560558 21660965 16717128 11030628 17107963
DCAF1 NF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 24912773 21750658 20178741 26549023 18332868
DDB1 COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
EME1 MUS81 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
EME1 MUS81 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
SLX4 ERCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23994477 24012755 21240275 24726326 22902628 23093618 19595721 19596235 25538220 20658648 19596236 19595722
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
NR4A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23071566 17139261
TP53 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17172872 17981789 15024021 22405092 20962589 24076372 23948487 15016801 22184120 19713933 16369493 23474762
PLK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22653443 19833129 16753148 23948487