SKP1
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791267
10023660
|
FAM168A
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
KRTAP4-12
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
FBXW5
|
MDFI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
FBXW5
|
S100B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
SKP1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7304783
18818696
|
TSC2
|
TSC1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
6547838
9580671
|
CUL1
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22474075
21145461
|
CUL4A
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22474075
21145461
|
NFM
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
TXIP1
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
DEFB1
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
NDEL1
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
FBXW5
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23314863
33504946
|
FBXW5
|
TSC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24372178
18381890
|
MAP3K7
|
NLK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
ZNRF1
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
FBXW5
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
18381890
17079684
22910413
|
SRFB1
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
OD3L2
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
HSPB9
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
PLEKHF2
|
TNFAIP8L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
CUL4A
|
DCAF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
DDB1
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.85
|
STRING
|
36370105
|
CUL4A
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17079684
32235678
21145461
|
FBXW5
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
23314863
18381890
17079684
22910413
|
WDR20
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19615732
28514442
33961781
|
CUL1
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
HSP90AA1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
FBXW5
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29103612
25143387
14603323
25515538
21145461
23314863
23319600
|
DDB1
|
DCAF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
16964240
19966799
16949367
30945288
28514442
|
FBXW5
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
EFEMP2
|
MDFI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
KRT31
|
KRTAP4-12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
KRT31
|
KRTAP9-3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
FBXW5
|
UBE2R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RBX1
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
EFEMP2
|
KRTAP10-8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
KRTAP10-8
|
VWC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
KRTAP4-12
|
KRTAP9-3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
KRTAP10-8
|
KRTAP4-12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
KRTAP10-8
|
KRTAP12-3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
KRTAP1-3
|
KRTAP4-12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
KRTAP1-3
|
KRTAP10-8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
KRTAP1-3
|
KRTAP9-3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
SKP1
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
7304783
18818696
|
KRTAP10-8
|
KRTAP9-3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HuRI
|
32296183
|
RBX1
|
UBE2R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
DCAF4
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
SKP1
|
FBXW5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
33961781
15070733
20596027
22388891
32350066
31210753
23314863
30596474
26087183
23319600
27705803
10531037
19159283
22632967
|
NLK
|
MYB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15082531
15308626
16055500
|
DDB1
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
TSC1
|
TSC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
CUL4A
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
CUL1
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CUL4A
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
RBX1
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
CUL1
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
14536078
15071497
15147722
15340381
15459660
15489953
15668399
15688063
15703371
16697054
17053147
17884153
18636226
18787170
18931676
19150432
19270156
19622404
19686080
19797085
19809470
19847258
|
RBX1
|
CUL1
|
â—¼ SHARES_COMPLEX
|
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
CUL1
|
SKP1
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
14536078
15071497
15147722
15340381
15459660
15489953
15668399
15688063
15703371
16697054
17053147
17884153
18636226
18787170
18931676
19150432
19270156
19622404
19686080
19797085
19809470
19847258
|
RBX1
|
CUL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
RBX1
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
154.0
|
1.0
|
Omnipath
|
17053147
12684064
20638939
11967263
19797085
19258535
26540345
18826954
15071497
15448697
21765416
25730849
10230406
23343194
21169563
22270359
19250909
23732914
11359933
12051714
20006983
15361859
10748083
19352404
22682247
18787170
12504025
18636226
16469695
15459660
20211143
10535940
15001769
26725323
19411070
11861641
26159692
16697054
1570337
19751508
22822056
11348595
7542250
7641885
19849719
16759355
12820959
17452440
19622404
15703371
10648623
19245792
23331499
9694792
19150432
23180781
19597341
16189514
22474075
18988627
22767593
17143292
24949976
10713156
23770852
22405651
19942853
18196958
20399188
16713974
26192618
11027288
17884153
19933270
22730322
21411632
11961546
17936032
19809470
15147722
19270156
19576224
11483504
20976471
12504026
24023259
12840033
15340381
12904573
20558317
11900249
14536078
19686080
12565873
18805092
15489953
19557001
26885856
17652783
12481031
20843316
11955436
21071413
16039586
11956208
20705860
8666229
17928543
10023660
19836308
16940750
12706828
19143635
15688063
10671552
16123592
19366350
19847258
12417738
11245432
20832730
12648680
12609982
19619488
10230407
18931676
|
SKP1
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
9663463
19945379
12684064
19270694
16759355
23951410
10648623
11961546
26540345
26976582
26474281
17290223
9736735
21169563
14685242
16357137
21145461
29070679
15452136
15966899
12628165
21778237
22474075
16189514
22767593
11359933
9430629
10713156
10023660
10228155
12504026
18818696
9827542
12504025
18094045
10066435
23324393
23770852
9990852
12417738
27705803
9636170
21249194
12904573
34499862
11027288
26725323
20832730
19933270
12609982
10230407
|
RBX1
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
DDB1
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
RBX1
|
CUL4A
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
DDB1
|
CUL4A
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
RBX1
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19270156
19440234
19557001
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
RBX1
|
DDB1
|
â—¼ SHARES_COMPLEX
|
|
|
27.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19270156
19440234
19557001
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
FBXW5
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17244613
19232515
33962073
|
MAP3K7
|
NLK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
17145710
11071635
23331499
15082531
25241761
12482967
15764709
11404460
15640443
20194509
10391247
10823839
7693453
12709429
10377264
|
NLK
|
MYB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
17145710
15308626
15082531
12482967
|
RBX1
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
24.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
14536078
15071497
15147722
15340381
15459660
15489953
15688063
15703371
16697054
17053147
17884153
18636226
18787170
18931676
19150432
19270156
19622404
19686080
19797085
19809470
19847258
|
RBX1
|
TSC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
12906785
15340381
15459660
15688063
15703371
16636147
16697054
17680028
17884153
18381890
18931676
19022819
19440234
19622404
19686080
19809470
19847258
20146692
20211143
|
RBX1
|
SKP1
|
â—¼ SHARES_COMPLEX
|
|
|
24.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
14536078
15071497
15147722
15340381
15459660
15489953
15688063
15703371
16697054
17053147
17884153
18636226
18787170
18931676
19150432
19270156
19622404
19686080
19797085
19809470
19847258
|
RBX1
|
TSC2
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
12906785
15340381
15459660
15688063
15703371
16636147
16697054
17680028
17884153
18381890
18931676
19022819
19440234
19622404
19686080
19809470
19847258
20146692
20211143
|
TSC2
|
TSC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
12150915
12172553
12869586
12906785
14551205
14651849
15342917
15611338
15851026
16556040
16636147
16678438
16959574
17604271
17680028
17693255
18198340
18481918
18692468
18974095
19022819
19027299
19339977
20146692
21533173
21621563
21708191
23030059
26597054
27328425
9069260
|
TSC2
|
TSC1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
31.0
|
1.0
|
ACSN
|
12150915
12172553
12869586
12906785
14551205
14651849
15342917
15611338
15851026
16556040
16636147
16678438
16959574
17604271
17680028
17693255
18198340
18481918
18692468
18974095
19022819
19027299
19339977
20146692
21533173
21621563
21708191
23030059
26597054
27328425
9069260
|
TSC2
|
TSC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
84.0
|
1.0
|
Omnipath
|
12167664
16424383
12511557
21134130
14551205
10915759
11741832
15340059
20166753
23331499
15342917
9580671
21071413
16464865
15851026
11290735
9809973
15851513
12869586
10807585
15963462
10585443
11741833
20412061
20226003
11175345
25263562
16339216
18411301
16636147
14651849
17658474
17693255
12176984
17077083
|