COPS6
|
MYCBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
ASXL1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
ERBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16729043
5218694
|
GRB2
|
CFL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
DLST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
DLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
MYC
|
MYCBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15979100
20562918
|
SSRP1
|
MYCBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
CTNNB1
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16983094
0606850103
|
PRKAR2B
|
AKAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9065479
9326583
|
ARFGEF2
|
ARFGEF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19332778
0901558106
|
CFL1
|
MYCBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
RIN1
|
ERBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
LEF1
|
MYCBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15979100
|
GDF9
|
MYCBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
DISP3
|
MYCBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
PTN
|
MYCBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
ARHGEF40
|
MYCBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
MIR22HG
|
MYCBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20562918
|
MYC
|
CTBP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
34147029
|
MYC
|
IDH3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
MYC
|
SSRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
MYCBP
|
AKAP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
12740381
|
HEXI2
|
MYCBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CS
|
MDH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
DLAT
|
OGDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
CS
|
SUCLG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
CS
|
IDH3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
SDHB
|
SUCLG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
855.0
|
0.85
|
STRING
|
36370105
|
IDH2
|
IDH3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
RIN1
|
ERBB3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16273093
31980649
|
IDH2
|
IDH3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
BIG1
|
MYCBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16866877
33961781
|
MYCBP
|
BIG2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16866877
33961781
|
AKAP1
|
PRKAR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
MYC
|
AKAP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21150319
17314511
30415952
|
SDHA
|
SDHC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
IDH3B
|
IDH3G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
16189514
16713569
31536960
10677231
33961781
26186194
|
ACO2
|
GOT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
IDH2
|
IDH3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
IDH3A
|
MDH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
ERBB3
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9756944
24189400
24658140
16729043
11173924
|
BIG2
|
BIG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10716990
22084092
19332778
|
MYBPP
|
MYCBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
12151104
12223483
|
OTUD4
|
MYCBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29395067
19615732
33961781
|
SDHB
|
SDHC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
MYCBP
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9797456
32140074
12223483
|
MYC
|
PDHA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
AKAP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
ACO2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
SDHD
|
SDHA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23747254
25564869
23564345
|
SDHD
|
SDHC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23747254
25564869
23564345
|
MYCBP
|
AKAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11483602
12223483
12414807
|
DLAT
|
PDHA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ACO2
|
FH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
CS
|
PDHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
CS
|
IDH3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
DLAT
|
DLST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
ERBB3
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
DLAT
|
DLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
IDH3B
|
IDH3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
DLD
|
PDHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
DLST
|
OGDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
CTNNB1
|
LEF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
DLAT
|
PDHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PDHA1
|
PDHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
IDH3A
|
IDH3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
ERBB3
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
9756944
24189400
11173924
24658140
14967450
16729043
|
MTOR
|
IDH3A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
23.0
|
1.0
|
ACSN
|
12150925
12408816
12906785
15755954
16469695
17604271
17680028
18372248
18492954
19022819
19446321
19568798
19706736
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MYC
|
LDHA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
11274345
11283613
11283614
11704864
15199147
16782875
17055429
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
25002027
28536364
8955077
9192621
|
MYC
|
SLC1A5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
11274345
11283613
11283614
11704864
17055429
17558397
17873522
19033189
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
25002027
28536364
|
CTNNB1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
21533051
19778454
16510874
12095419
17360646
18852287
15576399
19561604
20300972
19662654
15579438
17724465
9727977
24447505
18679417
12907606
|
LEF1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19620402
18202148
17132729
19653274
|
MYC
|
LDHA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16319523
9723176
11085504
14519204
11983916
9192621
|
MYC
|
VHL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22286234
12695333
|
MYCBP
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12223483
9797456
20562918
|
CTNNB1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
19751508
7542250
11967263
22290435
19623618
16574648
23343194
11955436
22270359
22761862
16039586
15810077
17143292
12051714
8666229
22943793
15576399
21151179
16940750
17306568
17666529
21285352
19619488
|
LEF1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
19751508
7542250
11967263
22290435
19623618
23343194
11955436
22270359
22761862
16039586
15810077
17143292
12051714
8666229
22943793
15576399
21151179
16940750
17306568
17666529
21285352
19619488
|
MYC
|
LDHA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16782875
17093053
15199147
8955077
9192621
|
IDH3B
|
IDH3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
28514442
16713569
31515270
14681455
33961781
26186194
10601238
14555658
|
IDH3A
|
IDH3G
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
28514442
10677231
14681455
28098230
33961781
26186194
14555658
26344197
|
PDHA1
|
DLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11752427
2188967
11935326
9242632
|
CTNNB1
|
LEF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17785445
15473860
11326276
17335794
15728254
|
CTNNB1
|
LEF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
16510874
23151663
11751639
15735151
17143293
16204248
23331499
12556497
21071413
14638683
15768032
18296023
12748295
21743491
11835406
16510875
18077326
8757136
9065403
20123964
15728254
17517646
21078818
15684397
8892228
10890911
15525529
12077367
9419974
|
PDHA1
|
DLAT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11752427
2188967
11935326
9242632
|