Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
WRN RAD52 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216387 12750383
WRN RAD52 â—¼   COLOCALIZATION 2.0 0.8 intact 5216387 12750383
PIF1 PRSS1 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
SSA27 PIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SSA27 RTEL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBXO18 PCNA â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
PTGES3 TERT â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
PCNA XRCC6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11239001 24695737 12171929
WRN XRCC6 â—¼   PHOSPHORYLATION ✅ 0.86 0.86 mint 10783163 5212534
RAD52 WRN â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HSP90AA1 TERT â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
BLM RAD52 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
WRN PCNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12633936 12750383 16713569 10871373 20600238
WRN XRCC6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
PIF1 CYP27A1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
HSP90AA1 PTGES3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PCNA WRN â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 10858306 11283614 11585362 11756412 11948190 12202749 12637553 14624239 14726013 15385537 15703371 15871698 16216273 16442856 16449207 16697054 17055429 17116323 17426133 17599061 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19748837 19847258 20027199 20056333 20064462 20691907 20713526 20955519 21376743 21727086 2191300 21922195 22021614 22455312 22657828 22743550 22973052 23082994 23110144 23161013 23253856 23414611 23485469 24036544 24050180 24709898 9407949
PCNA EXO1 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 11438669 11756412 14624239 14676842 14726013 15474417 15703371 16697054 18048416 18087292 18584027 18756267 18809224 19490890 1974050 19772495 19847258 20019063 20478261 22021614 23414611
PCNA WRN â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 10858306 11283614 11585362 11756412 11948190 12202749 12637553 14624239 14726013 15385537 15703371 15871698 16216273 16442856 16449207 16697054 17055429 17116323 17426133 17599061 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19748837 19847258 20027199 20056333 20064462 20691907 20713526 20955519 21376743 21727086 2191300 21922195 22021614 22455312 22657828 22743550 22973052 23082994 23110144 23161013 23253856 23414611 23485469 24036544 24050180 24709898 9407949
PCNA EXO1 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 11438669 11756412 14624239 14676842 14726013 15474417 15703371 16697054 18048416 18087292 18584027 18756267 18809224 19490890 1974050 19772495 19847258 20019063 20478261 22021614 23414611
BLM PCNA â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 22973052 23253856 24089143 24095737
PCNA EXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20970388 16189514 15225546
BLM EXO1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11438669 14676842 15474417 15496928 15549137 15655342 16697054 18001825 18048416 18087292 18171670 18212739 18584027 18756267 18809224 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 20019063 20021983 20064462 22266823 22657828 23253856 24089143 24095737
BLM WRN â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 22973052 23253856 24089143 24095737
PTGES3 DKC1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
PTGES3 DKC1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
PTGES3 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16565516 10642522 11447118 26804907 15916966 11413142 16403413 21988832 11812147 19875381 19740745 14761955 12077419 10811660 20039095 22806877 25036637 20048054 19996313 18285346 20661446 22315411 23022381 18172314 20159553 22729780 22504172 16289154 9817749 14987994 8114727
PIF1 RTEL1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 23657261 17172855 16522649 20524933
WRN RAD52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 12750383 12919958 17118963
PIF1 P4HA1 â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
PIF1 AES â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
PIF1 PDPN â—¼   KO_DOWN_REGULATES ✅ - -1.06 1.05 PKG 28854368
EXO1 PIF1 â—¼   KO_UP_REGULATES ✅ + 1.16 1.16 PKG 28854368
PIF1 FN1 â—¼   KO_UP_REGULATES ✅ + 2.37 2.37 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368