Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
POLB WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PUM1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 SDCBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 EIF2S2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 FTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 CLINT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT ECH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
HTT EIF2S2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 EIF5B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 FTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT FTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GADD45A FTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MAP3K12 FTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TAF10 FTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PTN FTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SNCA FTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD9 FTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
FTL PSEN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIK3CA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT SDCBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
WFS1 PUM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 SDCBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA SDCBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 ZDHHC17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HERC2 NCOA4 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
FTH1 NCOA4 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
HERC2 DISC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17043677 31413325 90000000
DISC1 NDEL1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
NHEJ1 NCOA4 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
MDC1 ACO1 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
EIF2S2 EIF1AX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 641056 592399 429297
PTN GADD45A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PTN PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11280786 11110708 18097461
FTL MEOX2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
NHEJ1 EIF1 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
PSEN2 PSENEN â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
EIF1 EIF5 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
FTL FTH1 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 8153045 21516116
EIF2S2 EIF5B â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
EIF1AX EIF5B â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
NHEJ1 FTL â—¼   KO_UP_REGULATES ✅ + 0.93 0.93 PKG 28854368
EIF1AX EIF2S2 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
EIF1 EIF1AX â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
EIF1 EIF2S2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
NDEL1 DISC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 29961565 33961781 32296183 17043677 31413325 20880836 90000000 12506198 14962739 28514442 12812986
NHEJ1 NOP53 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
EIF2S2 EIF5 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
MDC1 FTH1 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
DISC1 NDEL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 12812986 17043677 12506198 31413325 20880836 29961565 14962739 17202468
EIF5 EIF2S2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10805737 11092890 9395514 16189514
FTH1 FTL â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 17603935 26653790 26794443 27048822
FTH1 FTL â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 17603935 26653790 26794443 27048822
PIK3CA RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15854902 19225151 20097763 21123297 30021155 24990947 20068231 19079619 15809305 20599721 14623952 11279232 34518212 33800846 18669648
POLB FTL â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
MDC1 NCOA4 â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
EXO1 FTL â—¼   KO_UP_REGULATES ✅ + 1.15 1.15 PKG 28854368
MDC1 FTL â—¼   KO_UP_REGULATES ✅ + 1.49 1.49 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368