Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
MYC LAMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11085504
MYC FTH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9924025 12110671
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
AP1B1 DNM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10398591 11050117
WFS1 FTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AP2B1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
GGA3 TGOLN2 â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
ESR1 WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 CLINT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VTI1B CLINT1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
WFS1 PUM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC AP2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 30415952
MYC JUN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
MYO6 EPS15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26950368 29467281
MYO6 AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26950368 11967127
CFTR AP1B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
AP2A1 AP1B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
FGFR2 FGFR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CLINT1 PICALM â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
EPS15 AP1B1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12538641 33961781 19380743
CLTC MYO6 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
AP1G1 CLTC â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
AP2B1 CLTC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ESR1 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
GGA2 GGA3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14638859 31076515
ESR1 MED4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
ESR1 MYH9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21182205 19805454 25604459
CFTR MYH9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22038833 29924966 26618866
GGA1 GGA2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
EPS15 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 19380743
AP2A1 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 26344197
AP1B1 AP2A1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CLTB CLTC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
AP2A1 AP2B1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DYNLL1 DYNLL2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
JUN ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17317669 11477071 16713569 23747343
EPS15 AP2A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10764745 19380743 10953014 8662627 9049247
GGA1 GGA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14638859 33961781 28514442
CLTC GGA1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PICALM CLTC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16491119 10436022
EP300 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27956703 21268080 21937452 24069158 11689449 14630807 11980644 10327051 12437352 12471036 24636898
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
MYC FGFR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CLINT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
ESR1 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21737465 21947652 22878616
ESR1 ODF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
AP2A1 EPS15 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
DYNLL1 GABARAPL2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
AP1G1 AP2B1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
DYNLL2 GABARAPL2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
FTL FTH1 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 8153045 21516116
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
AP1G1 AP2B1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 34079125 33961781 26344197
AP1G1 AP1B1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10535737 10747088 9733768 7593184 23415225 11409905 33961781 22939629 26344197
CLTC GAK â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
AP1B1 AP1G1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
CLTC AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
FTH1 FTL â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 17603935 26653790 26794443 27048822
FTH1 FTL â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 17603935 26653790 26794443 27048822
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
AP2A1 CLTB â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720