Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAD9A CLSPN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20424596 7897378
MRE11 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
MRE11 ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
BLM ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
BRCA1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TOP3A ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR RMI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR BRCA1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 23422745
TOP3A ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
BLM ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
WRN ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP RMI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TOP3A FANCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8140640 21240188
MYC MSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12808131 11983916
XPA PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0915085107 20304803
WRN RAD52 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216387 12750383
WRN RAD52 â—¼   COLOCALIZATION 2.0 0.8 intact 5216387 12750383
MDC1 LMNA â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
P53 LMNA â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 29568061 30419336 25144556
RFA1 PRP19 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24443570 26474068 24332808 28666352
RFA2 PRP19 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24443570 24332808 28666352
RFA2 CLSPN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24126761 20679368
RFA1 CLSPN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24126761 20679368
MYPT1 RFA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 24332808
RBCC1 P53 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21775823 20614030
P53 TOP3B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34709727 32807901
MYC SSBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
SSBP RFA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 24981860
SSBP RFA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 24981860
SSBP XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 24981860
SSBP RFA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 24981860
RPR1B RFA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 24332808
RFA1 ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19338310 24332808
RFA1 TOP3B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 34709727
RFA1 MDC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29656893 24332808
RBCC1 RFA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34226595 20562859
MYC RFA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
ACTB RFA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19338310 24332808
RBCC1 RFA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34226595 20562859
RFA3 TOP3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24126761 24332808
RFA3 RMI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24126761 24332808
RFA3 ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19338310 24332808
TP53B XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22990118 29656893
MYC PRP19 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
PRKDC MRE11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10608806 20808282
XRCC6 MSH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 21075794
MYC MSH3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC PRKDC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MSH3 PCNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
DPOLA P53 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16713569 11917009
XRCC6 P53 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11751391 15782130 32807901
KIN17 RFA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15831485 12754299
RFA1 SMAL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24981860 24332808 24126761 26474068 21504906 29576527 27723720
RFA1 XRCC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30585729 24981860 24332808
DPOLL RFA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17507928 27173435
RIP RFA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FANCA RFA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22705371 12973351 12724401
ATR RFA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17035231 24332808 15929725
RFA2 XRCC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26344197 10064605 24981860 24332808
RFA3 SMAL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24126761 29576527 24332808
RFA3 WRN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24126761 30279242 27173435 24332808
MYC TP53B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29656893 29467282 20195357
MYC LMNA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
RAD9A PCNA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12400013 16189514 11994305
RFA1 PCNA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11254741 20227374 15831485 21504906 24958773 12171929
LMNA PCNA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24623722 29753763 30419336
PCNA XRCC6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11239001 24695737 12171929
RFA1 HELB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24126761 12181327 27723720
RFA2 WRN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24126761 30279242 20802463 24332808
RFWD3 RFA3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28575658 24332808 24126761 21504906 21558276 29576527
MYC ACTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29467282 11839798
MSH2 BLM â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15064730 10783165
PRKDC BRCA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25223785 10608806
LMNA MDC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30179224 30419336 22412018
MDC1 RAD51 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28973861 16186822
DPOLA RFA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12641457 17666013 24332808
FANCJ RFA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17596542 20159562
FANCA BLM â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22705371 12973351 23509288 22343915 12724401
BLM MYC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 30415952 29467282 23750012
BLM TOP3A â—¼   COLOCALIZATION ✅ 0.85 0.85 mint 20711169 8048867
BRCA1 WRN â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
BRCA1 FANCA â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
RAD52 CLSPN â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
BRCA1 CLSPN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15096610 22863316 16713569
WRN XRCC6 â—¼   PHOSPHORYLATION ✅ 0.86 0.86 mint 10783163 5212534
BRCA1 MSH2 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
DPOLL PCNA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16189514 16174846 12081642 12368291 11784855
CLSPN RAD9A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20424596 12766152
RMI1 RFA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24126761 15775963 24332808
BLM RFA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24332808 12724401 24126761 28506294 30279242 15775963
RMI1 RFA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24126761 15775963 24332808
BLM RFA3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24332808 12724401 24126761 30279242 15775963
BRCA1 MSH3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 14578343 11498787
RAD52 WRN â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATR BRCA1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PRKDC P53 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9765199 19918261 10470151 10713094 9363941 9744860 10601022 11551930 11709713 10951572 16713569 8940078 25362358 11751391 12756247 10673501 10747897 9679063 11883897 10608806
TP53B RFA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15856006 29656893
RFA1 MSH2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 24332808
LMNA RFA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29568061 26344197 34079125
RAD9A RFA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18936170 15897895
MSH3 RFA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22939629 24332808
TIPIN RFA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24126761 17296725 20679368
BRCA1 RFA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23901102 19369211 29656893 21240188 19766185
TP53B RFA2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15856006 29656893
FANCJ BLM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24895130 21240188
MRE11 BLM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10783165 28506294 29523790
BRCA1 BLM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25084169 29656893 26831064 10783165
WRN PRKDC â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10608806 11889123
ATR ATRIP â—¼   PHOSPHORYLATION ✅ + 0.88 0.88 Signor 15451423
MYC P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28205554 28628118
TOP3A RFA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24126761 24332808 12724401
ATRIP RFA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23723247 25916848 26854234 12791985 17526493 31757956 24332808 22258451 16407120 15743907 18936170 21859891
PRKDC RFA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12641457 10064605 24332808 21504906
RFWD3 RFA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28666352 28575657 28575658 24332808 24126761 26474068 30530694 21504906 21558276 29576527
ATR RFA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18162465 10608806 24332808
RFWD3 RFA2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28575657 28575658 24332808 24126761 26474068 21504906 21558276 28691929 29576527
RFA2 TOP3A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24126761 30279242 24332808
RAD52 RFA3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24126761 19338310 8702565
BLM TP53B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15364958 17984114 29656893
MDC1 TP53B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18986980 30179224 29656893 12607005 17925396
TP53B BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22884692 17525332 21552324 29656893 12364621 31009828 18001824 26831064
MRE11 XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30585729 10508516 26344197
BRCA1 ATRIP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17616665 29656893 24073851
MDC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21622030 17525332 15569676 29656893 12607005 19766185 12611903
MYC XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 17314511 29467282
BLM RAD52 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
WRN PCNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12633936 12750383 16713569 10871373 20600238
BLM P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15806145 11781842 12606585 22653443 15364958 12080066 24239288 16713569 32807901 11399766
ATR P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20798688 10435622 10673501 16293623 10747897 15775976 9765199 11883897 11551930 15159397 10608806 11709713 10951572 11459832 15082766
TP53B P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33606978 25837623 12110597 22653443 20307547 25651062 14985081 30252118 15364958 16713569 26022179 27546791 14978302 25579814 11877378 19433796 22084066 8016121 12351827 15611139 16169070 17805299
WRN P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11427532 15735006 12080066 16713569 11399766
P53 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14978302 9582019 14710355 21742769 18501503 9482880 14636569 9926942 16677609 26140185 19509300 15571721 16713569 16969499 31073355
P53 RAD51 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16983346 15064730 8617246 11948396 14636569 16600179 12606585 26140185 16713569 11002423 9380510 12750285
P53 RFA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8361542 8663296 15735006 23267009 9121469 11751427 15489903 32807901
RFA4 RFA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25499885 7760808 26186194 28514442
BLM RFA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11950880 10825162 15965237 25135477 12724401 24332808 12181313 24239288 24126761 26474068 30279242 15775963
WRN RFA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15965237 24332808 15735006 24126761 27723720 26474068 14499497 30279242 10373438
RFA3 RFA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24981860 22939629 26496610 7760808 21504906 19338310 12527904 26344197 8663296 20811460 8972858 8663111 24126761 11927569 2159011 10336450 9461578 27723720 12509449 26474068
XPA RFA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12527904 7876167 7665601 12641457 9535929 19446504 20304803 7565690 8972858
XPA RFA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10982866 33961781 12527904 7876167 20670893 32296183 19996105 11081631 9535929 20304803 7565690 8972858
RFA2 TIPIN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24126761 24910198 20679368
PRKDC RFA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10713094 8943020 24332808 16540648 11731442 10064605 9295339
RFA3 RFA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10982866 33961781 24981860 22939629 7760808 19338310 26344197 8663296 8972858 11081631 11173472 8663111 24126761 8157639 11927569 10449415 17976647 28514442 10336450 16189514 9461578 12509449 15965237 26186194 10064605
RFA2 SMAL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24981860 24910198 24332808 24126761 29576527
RFA4 RFA3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28514442 7760808 26186194
FANCJ BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18285836 22032289 19369211 17664283 29656893 20173781 11301010 14576432 17525342 28911102 17525341 25252691 27399284 30257991 20159462 20681793 15242590 16713569 19452558 21240188 15208681 15125843 14578343 17525340 17581638 23157317 11877378 24573678 26831064 22792074 17596542 15133502 23530059 18628483 16391231 14576433 25184681 18717574 28398198
MDC1 MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12607003 30179224 29656893 20081839 12607005 14519663 18583988
BRCA1 MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10426999 11353843 17349954 23530059 24413181 16391231 29656893 11504724 25184681 10783165
ATRIP ATR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17686975 14657349 15210935 17384638 20616048 17526493 18162465 21285353 26854234 19097996 18283122 15743907 15451423 14724280 15538388 28514442 23144622 15758953 19889979 18344416 20847938 11721054
RMI1 BLM â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20360068 20064461 20826342 23509288 26496610 24239288 20711169 15775963
RAD51 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11498787 31270457 19369211 14636569 24085845 29656893 28319063 25659039 34408138 31009828 9774970 16713569 25499220 19766185 17302439 9008167 28976962
MYC BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11916966 9788437 20215511 30415952 16713569 12646176 14612409
FANCA BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12354784 29656893 16713569 21240188
BRCA1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 9774970 9008167
MYC LMNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC MSH2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29467282 30415952 28205554 17314511 28628118 12584560
MYC PRKDC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
XRCC6 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8422676 20711232 19303849 26175416 28345663 30585729 17308091 22939629 26496610 10750018 15941674 33005030 21969602 15520013 10064605 21575865 26446488
ATR WRN â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MSH2 PCNA â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
RFA1 MCM2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 25963833 12614612
BLM RMI1 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 20711169 8048867
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
TOP3A WRN â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
PCNA MSH2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 8858149 16189514 12171929 15225546
WRN XRCC6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
ATR BLM â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
RFA1 MRE11 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 30179224 18936170 24332808 19586055
RAD51 RFA2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 19338310 9826763 15929725
RFA1 RAD51 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 19338310 9826763 12077133
MCM2 TIPIN â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
RAD52 RFA1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28551686 9826763 8702565 24126761 12139939 12077133
RAD52 RFA2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11081631 8702565 15929725 24126761 12139939
MSH3 MSH2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 16025128 8942985 22179786 22939629 8805365 14657349 9774676 10029069 19377479
RAD52 RAD51 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28551686 9826763 20190268 12750383 17118963 9837724 10666456 15766559 19338310 10212258 8550550 10448035
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
RFA2 RFA1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 7876167 24981860 22939629 26496610 28575657 7760808 21504906 22863883 12527904 20679368 26344197 8663296 25499885 24443570 20811460 30279242 8972858 12754299 32296183 8663111 24126761 11927569 2159011 28514442 10336450 9461578 27723720 12509449 15965237 26186194 26474068 10064605
BLM RAD51 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RMI1 TOP3A â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
FANCA RMI1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PCNA RAD51 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA WRN â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 10858306 11283614 11585362 11756412 11948190 12202749 12637553 14624239 14726013 15385537 15703371 15871698 16216273 16442856 16449207 16697054 17055429 17116323 17426133 17599061 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19748837 19847258 20027199 20056333 20064462 20691907 20713526 20955519 21376743 21727086 2191300 21922195 22021614 22455312 22657828 22743550 22973052 23082994 23110144 23161013 23253856 23414611 23485469 24036544 24050180 24709898 9407949
PCNA ATRIP â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA CLSPN â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA ATR â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA BRCA1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA ATRIP â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA CLSPN â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA ATR â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA RAD51 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA WRN â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 10858306 11283614 11585362 11756412 11948190 12202749 12637553 14624239 14726013 15385537 15703371 15871698 16216273 16442856 16449207 16697054 17055429 17116323 17426133 17599061 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19748837 19847258 20027199 20056333 20064462 20691907 20713526 20955519 21376743 21727086 2191300 21922195 22021614 22455312 22657828 22743550 22973052 23082994 23110144 23161013 23253856 23414611 23485469 24036544 24050180 24709898 9407949
PCNA BRCA1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BLM PCNA â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 22973052 23253856 24089143 24095737
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
ATR CLSPN â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATRIP CLSPN â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
TIPIN CLSPN â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15707391 20233725 12545175 22977173 21680713 16885023
CLSPN TIPIN â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
CLSPN MCM2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP CLSPN â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CLSPN â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
CLSPN TIPIN â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
ATRIP CLSPN â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CLSPN â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
CLSPN MCM2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CLSPN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18309293 24500207 19473886 12766152 18077418
XRCC6 MRE11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MRE11 WRN â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATR TIPIN â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
ATR ATRIP â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR MCM2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR TIPIN â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
ATR ATRIP â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
MSH2 ATR â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
ATR BRCA1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR FANCA â—¼   ENZYMATIC_REACTION ✅ 70.0 1.0 ACSN 11438669 11877377 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 15459660 15485915 15798197 15867354 16332722 16337602 16540648 16697054 16713580 16731533 16885023 17035102 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18157158 18448394 18469862 18472307 18511906 18543256 18550849 18677104 18716619 18756267 18931676 18995830 19004803 19217833 19225445 19258535 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 19847258 20019063 20051983 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957 9488723 9858600
ATR XPA â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR MCM2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
BLM ATR â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
ATR FANCA â—¼   UP_REGULATES ✅ + 70.0 1.0 ACSN 11438669 11877377 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 15459660 15485915 15798197 15867354 16332722 16337602 16540648 16697054 16713580 16731533 16885023 17035102 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18157158 18448394 18469862 18472307 18511906 18543256 18550849 18677104 18716619 18756267 18931676 18995830 19004803 19217833 19225445 19258535 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 19847258 20019063 20051983 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957 9488723 9858600
ATR MCM2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
MSH2 ATR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19847258 16612326 14657349 16713580 20478261 15703371 18543256 12947387 19473888 19595721 19596235 18157157 16697054 19596236 18406444 21285353
ATR MCM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 18309293 22179839 18691976 15448142 16899510 30062004 19690332 18077418 16446360 24685613 15210935 17525332
ATR RFWD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20173098 21558276 17478428
ATR ATRIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20616048 15451423 19889979 23144622 17686975 18344416
ATR FANCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 22615860 18677104 19622404 15798197 19793801 12972610 23253856 15136767 19282663 17116885 17582221 14988723 17384638 24095737 18931676 8020957 22266823 19109555 24089143 20832754 26194820 15459660 23444773 19772495 19847258 17296725 11877377 17102137 18550849 21948210 22657828 16697054 19686080 12535671
ATR BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 26927092 17478428 24746700 15159397 17531442 10866324 18677104 19622404 15798197 19793801 20860841 16713569 11114888 23422745 20936109 16322207 19282663 20068231 17116885 17582221 25879655 10608806 17384638 23346553 12773400 12183412 17525332 15459660 11278964 17296725 11877377 17102137 10550055 16522651
ATR XPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 19004803 27247238 18677104 19622404 15798197 19793801 23861882 23178497 27827925 18594563 19282663 17116885 17582221 18790090 17384638 20451471 19586908 15459660 16540648 17296725 11877377 24947324 17102137 30327428
ATR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12186630 22592045 22057367 24500207 18077418 16908529 15507430 29309644
ATRIP TIPIN â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
ATRIP MCM2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP TIPIN â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
MSH2 ATRIP â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
ATRIP MCM2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP MCM2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24073851 17616665
BLM RMI1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
BLM TOP3A â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12535671 12972610 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18550849 18931676 19217833 19270065 19282663 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCA â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM RMI1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
BLM FANCA â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM TOP3A â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12535671 12972610 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18550849 18931676 19217833 19270065 19282663 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM WRN â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 22973052 23253856 24089143 24095737
RMI1 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 15775963 23509288
BRCA1 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
FANCA TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
TIPIN MCM2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TIPIN MCM2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TIPIN MCM2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
XRCC6 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MSH2 MSH3 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
MSH2 MSH3 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
MYC RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 20940401
PRKDC WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 29043077 11889123 17570479 20516064 24429382 18157161
RAD51 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD52 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 15766559 17145710 9826763 20190268 17118963 10666456 12750383 9837724 19338310 10448035 10212258
WRN RAD52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 12750383 12919958 17118963
TOP3A RMI1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
TOP3A RMI1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
MSH2 MSH3 â—¼   KO_DOWN_REGULATES ✅ - -5.7 5.69 PKG 28854368
MSH2 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -6.48 6.47 PKG 28854368