Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SUMO1 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
ATM H2AX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1106300109 22451927
ATM H2AX â—¼   COLOCALIZATION 2.0 0.8 intact 16858402 5218840
ATM PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12147700
BLM PLK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16864798 0601828103
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
NBN EP300 â—¼   COLOCALIZATION 2.0 0.8 intact 21108945 8058069
EP300 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20488183
SUMO1 MDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
NBN SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RAD50 NBN â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
SUMO1 RAD50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
H2AX SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RAD50 ATM â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 18854157
ATM RAD50 â—¼   PHOSPHORYLATION 0.8 0.8 Signor 17570479
RAD50 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 10426999
EP300 H31 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16109717 30110629 11884585 23415232 15951563 27208796 15611041 11830591 28465257 19801601 16415179 27585400 15308690 20587414 19270680 28844863 24722339 15136563 23587423 30428346 20368990 11689448 23870121 12237408 11983172 18838386 16717280 21875947 14752096 8945521 16287840 30902546 29033323 15834423 12498683 10545121 23934153 14585496 11691934
SUMO1 TIF1B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19596686 24654937 21098080 21642969 18082607
TIF1B P53 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 20858735 17056014 32807901 20864041
BRCA1 H4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16628214 30804502
BRCA1 TIF1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
RFA1 MDC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29656893 24332808
SMRD1 MDC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 29656893
MYC RFA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RAD50 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC RIF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC SET1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
H31 RAD18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 29568061
H2AX RAD50 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16377563 19234442 31501894 15201865 10959836 18583988
H31 RAD50 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26527279 29568061
RFA2 RIF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20711169 16169070
TP53B XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22990118 29656893
P53 PAXI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19433796 32807901
TP53B SMRD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22990118 29656893
TP53B SET1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31076518 29656893
RT07 TP53B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TP53B MD2L2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29160738 29656893
THA10 TP53B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
RT07 UBP28 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ATM MDC1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 12607003
ATM RFA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10713094 9725899
PLK1 BRCA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25483079 24067368 31730000 29656893
BRCA1 RAD18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29656893 25184681 23901102
EP300 TP53B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16051665 29656893
MYC TP53B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20195357 29467282 29656893
PLK1 TOPB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 26811421
RFA1 XRCC6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 30585729 24332808
RFA2 XRCC6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26344197 24981860 10064605 24332808
XRCC6 P53 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11751391 15782130 32807901
TP53B TIF1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29955894 25905708 29656893
TOPB1 TP53B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11756551 29656893
TERA TP53B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34144977 23383273 29656893
NUP50 SMRD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NUP50 SET1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ATM NBN â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 10802669
BLM RAD50 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
BLM H2AX â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15364958 29523790
EP300 XRCC6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15023334 33742100 21988832
TP53B RAD50 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20010693 29656893
TP53B RIF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 29203878 29234018 29656893
H2AX H31 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23319141 31045206 20587414 20224553 29229926 16622419 26095369
RAD50 BLM â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29523790 25084169 10783165
BLM MYC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23750012 30415952 29467282
BRCA1 TOPB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23157317 19766185 29656893 33010150 25184681 16391231 11395493 12697828 23901102
EP300 RAD50 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 16051665
H2AX XRCC6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 23145133 15613478 33961781 18406329 20224553
TP53B RN168 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22884692 25999347 31501315 20016603 29499138 21552324 29656893
TP53B IF16 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7890747 8910340 29656893
MDC1 SMC6 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
NBN BLM â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29523790 10783165
EP300 H4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11163245 16096645 30804502 16109717 25728767 11884585 15951563 15611041 11830591 28465257 16415179 11689053 15308690 28844863 26625199 15136563 17982102 18397880 12499368 23587423 20368990 11689448 12237408 11983172 16717280 14752096 22100137 14612423 8945521 16287840 18418072 30902546 15834423 23934153 14585496 11691934 10607594 16332960
H2AX NBN â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 6805208 18583988
TP53B NBN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20010693 20081839 29656893
H2AX NBN â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 22565321 8391733
NBN H2AX â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 22157895 8303386
SMC6 TP53B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26496610 29656893
MSL1 TP53B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19650074 29656893
ATM H2AX â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16858402 27918549 22184063 9488723 32518374 20081839 18344987 21676867 22451927 21704408 11571274 11893489 26095369
BLM RFA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12724401 24126761 30279242 15775963 24332808 28506294
BRCA1 IF16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14654789 27764250 26121674
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
MYC TIF1B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 17314511 29467282
IF16 XRCC6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25665578 31665637 30585729
NUP50 TP53B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 34079125 26186194
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATM BRCA1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 NBN â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 BLM â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25084169 10783165 26831064 29656893
BLM RIF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20711169 23509288
BRCA1 RFA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23901102 19766185 19369211 21240188 29656893
NBN EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21108945 16051665
TOPB1 MDC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21482717 24239288 27590578 29656893
MYC PLK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27773673 17314511 33494392 29467282 30415952
SET1A P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29474905 31076518 23870121
TP53B RFA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15856006 29656893
TP53B RFA2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15856006 29656893
ATM BLM â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MDC1 ATM â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29656893 14519663 28943310 12607005 26734725 18006705
BLM TP53B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15364958 17984114 29656893
NBN BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10426999 18171670 19244116 12124328 10783165 25659039 25184681 25939603 11504724 29656893
TP53B BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22884692 31009828 12364621 17525332 26831064 21552324 18001824 29656893
MDC1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21622030 19766185 15569676 12611903 17525332 12607005 29656893
BRCA1 SUMO1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26831064 18025037 20016594
MDC1 TP53B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 30179224 18986980 17925396 12607005 29656893
MYC XRCC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17314511 30415952 29467282
MYC P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28628118 28205554
PLK1 TP53B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25659891 26291670 25607646 32707033 20126263
RAD18 TP53B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19228710 29656893
SUMO1 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 15144954 23543742 22214662 23604351 15017387 12917636 16732283 18583933 11867732 10961991 10562557 17369817 20972456 19246003 19684601 23825024 10788439 15242646 23150668 15327968 15576338 16122737 17060459 21316347 16713569 15931224 20861261 23772552 32807901 20534433
SUMO1 TP53B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20016603 29656893 24654937
H31 XRCC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20080577 29568061 21187428 33961781 34079125 26527279 25281560 20504901
TP53B H2AX â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21566653 17024177 31009828 15364958 21317870 28242625 21623170 20075863 29662616 12607005 29499138 18001825 12447390 26734725 18001824 12697768
H31 TP53B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16415788 17190600
UBP28 TP53B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33606978 27546791 16901786 19615732 29656893
SDOS TP53B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 28241136 28213517 31911551 33961781
MDC1 RAD50 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
ATM BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11114888 11278964 29656893 10783165 11016625 10866324 10550055 15713674 18344987 10608806 17478428
ATM NBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24800743 10783165 25088203 11252893 30952868 10608806 17507690 22464731 25895060 10839545 15758953 10839544
ATM TP53B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20010693 12697768 11042216 20081839 18996087 22621922 12447390 29656893
ATM BLM â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29523790 10783165 12034743
ATM P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28654064 11551930 14744854 27559048 11875057 15790808 11459832 11709713 9765199 23525106 21383020 25086746 10864201 23907539 15064416 10713094 24469230 15159397 20010693 10673501 19965871 17157788 9843217 15632067 23890999 10608806 10744722 16858402 16713569 17409407 15713674 30252118
BLM P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 12080066 15364958 22653443 12606585 24239288 11399766 11781842 15806145 32807901
BLM RFA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11950880 24332808 12724401 25135477 24126761 24239288 30279242 12181313 26474068 15775963 10825162 15965237
H2AX BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12485996 34321665 19766185 18001824 31501894 11927591 18344987 20681793 26095369 18001825 29499138 19805520 26121674 10959836 12419185
EP300 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 19887647 10655477 11782371 16713569 21212407 22787115
P53 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14710355 16713569 21742769 15571721 26140185 9926942 9582019 14636569 14978302 16677609 18501503 9482880 19509300 16969499 31073355
TERA BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29180510 10855792 16713569 26831064
MYC BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12646176 11916966 16713569 20215511 9788437 30415952 14612409
BRCA1 RAD50 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10426999 18171670 12124328 16713569 10783165 25084169 25184681 16260778 16391231 11504724 29656893
EP300 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9809062 15295102 21471221 26229107 15337767 23010591 18485870 15558054 22266186 15509808 26625199 9194564 23402884 23870121 17438265 16959611 12690203 17906639 24821727 15664194 21187340 33196849 17977830 11804596 25288747 15186775 18612383 23796514 19234109 27818144 19339993 24157709 9652736 28757384 12499368 17452980 9891054 23880760 31167125 15542844 22013068 16713569 9288740 17189186 11782467 16543236 23329847 10942770 26302407 23307557 22074660 19218448 19217391 10601022 16024799 16782091 12501250 11433299 22731250 23728348 10518217 9194565 25651062 12724314 14612423 16611888 19805293 18243116 32807901 29706626 20234175 16678111 14759370 25867071 25156994 11907332 16438982 16135789 11070080 11359905 25753752 16537920 9744860 18391200 15965232 10490106 16928824 12162806
MDC1 RAD50 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30179224 29656893 14519663 12607005 12607003 18583988
MDC1 H2AX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21622030 16377563 19234442 28242625 32518374 20159462 21676867 12475977 14519663 15201865 12607005 21293379 30598506 18001825 29499138 26734725 18001824 18583988
MDC1 NBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15377652 30179224 12607003 18678890 29656893 27590578 25064736 20460517 19804756 23115235 14519663 15201865 12607005 20224574 18001824 18583988
NBN H2AX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11110662 18583988 15733840 16377563 31501894 20081839 23145133 22157895 22941933 21676867 16932743 15201865 18001825 18001824 12419185
P53 PLK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22653443 15024021 16753148 19833129
PAXI1 TP53B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15456759 17925232 17500065 14576432 34144977 26344197
TP53B P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22084066 12110597 26022179 15611139 33606978 22653443 14985081 17805299 25579814 20307547 11877378 15364958 8016121 25651062 16169070 16713569 27546791 19433796 25837623 14978302 12351827 30252118
P53 RFA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11751427 8663296 15735006 8361542 23267009 32807901 15489903 9121469
P53 IF16 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 11146555 30193098 21397192
TP53B H4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27153538 16415788 27248496 25579814 31911551 23760478 25651062 17190600 23377543
TP53B DYL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33961781 30464262 15611139 26496610
ATM NBN â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
MDC1 NBN â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
NBN RAD50 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
H2AX H4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 27248496 20000738 24981860 33961781 30021884 20224553 18285460 16522924 26095369
NBN MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20224574 7891431
H2AX MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6805208 18583988
RAD50 NBN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30179224 12607003 12124328 11238951 17612497 22941933 23530059 24651726 15758953 11062235 10426999 10783165 22464731 19197236 12447395 12679336 26215093 22939629 34348893 17526493 17500065 9705271 16391231 30440001 24981860 26344197 15734743
RFA2 RFA1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 20679368 8663296 10064605 12754299 12509449 27723720 12527904 15965237 9461578 21504906 32296183 25499885 24126761 30279242 26496610 24443570 8663111 10336450 2159011 11927569 7760808 22939629 26474068 20811460 7876167 8972858 22863883 33961781 26186194 24981860 28575657 26344197
H31 H4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 8598932 25416956 30804502 23319141 27248496 16622419 19498464 20080577 14578449 29568061 21724829 19410544 26527279 18571423 25533843 19766566 22828868 14718166 20739937 33961781 20498094 34079125
XRCC6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H2AX ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
BRCA1 ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
ATM MDC1 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM RAD50 â—¼   PHYSICAL_INTERACTION 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM MDC1 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM RAD50 â—¼   SHARES_COMPLEX 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM BRCA1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM MDC1 â—¼   ENZYMATIC_REACTION ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM MDC1 â—¼   REGULATES ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM RAD50 â—¼   REGULATES ✅ 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
ATM NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 12433983 12861053 17485521 23146902 10839545 19413330 15302935 27602502 17429352 19523210 24360018 20068231 17507690 17570479 10608806 12598907 18669648 25088203 18003706 11252893 17431132 23097684 10766245 12814430 10802669 21664921 26512707 10839544 11927276 21130714 17525332 12447395 14707289 15733840 15279770 25119968 18644472 28822740
ATM BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16199871 11146546 25766002 17984114 14643436 20719863 17363339 14729972 18054789 12034743 30496191 16880735 11375976
ATM H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 197.0 1.0 Omnipath 27410735 28544233 16426903 28797244 9488723 23847653 30197789 21930799 18158901 21693595 18848500 22819196 15603757 16760673 17570479 24688021 24793032 27458206 16531125 22028490 30154456 19230794 23202908 25852739 19059218 26073471 22247744 28259974 29584802 25691887 19049966 20368801 26700820 29386061 28124509 20613862 27550454 20847938 27388041 27752097 23269287 24480460 22237206 20461094 20971043 26941327 18285803 21690091 15279774 23891287 25847270 24490130 25349305 26906421 20637859 26314960 15286739 27780918 20454618 30013081 28671946 25218945 23742011 26391293 23972723 23382699 26416514 27442013 20703100 24726884 26512707 27332952 29641431 25287622 26295265 14643438 29163809 25264544 19895790 26504743 26113859 27431324 28790385 18413980 21283714 21787120 20205745 19781914 25093845 27135971 23227178 22224778 20923785 20860841 24244154 23386996 30065307 16858402 11879731 28009280 23343929 20192759 22761798 26855420 24378750 20068231 20580718 14504478 24893124 29048667 25661368 26860083 26019182 20488183 28764946 22205726 23977391 18471973 19591958 28239143 20542002 17525332 20495376 18755145 23050241 17782711 11571274 19473884 28431265 25742493 18248856 17690115 20684759 26317467 21727091 24651472 25827888 27164092 28587922 20976184 30723510 20471486 23772364 29794999 11893489 19014481 20165693 26671524 16997395 20936109 26114388 23845989 15138496 22761813 23355489 27455285 28943310 21348461 19647519 23678292 23166506 28099474 29434792 25249630 25269479 27310012 15177039 22559321 26045162 20865059 22972376 21148072 26760771 21188122 22962268 22768044 26711340 20460517 27845910 28855246
ATM RIF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18077418 15342490
ATM BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 26927092 17303408 15159397 24746700 12024016 10866324 30197789 12919958 11114888 26745677 26383678 34301763 12427729 11313470 16163361 28035057 20068231 25939603 26320175 17570479 19683496 22743550 10608806 23802008 23847781 21203981 15964794 12183412 12607003 17525332 19996295 15459660 11278964 19651622 21706030 11877377 20952512 10373534 19622773 10550055 27170701 15212693 23704879
ATM RAD50 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17570479 17081983 15302935
ATM MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 28193847 21705321 22234877 12607003 12607005 22234878 17525332 18006705
NBN BLM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 BLM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
NBN BRCA1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
RAD50 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10783165 16260778 16391231 10426999 11504724 25084169 25184681 16713569
BRCA1 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18001824 18001825 17145710 12419185
EP300 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20471956 16051665 21108945
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
RAD50 MDC1 â—¼   PHYSICAL_INTERACTION 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
XRCC6 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MDC1 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RAD50 MDC1 â—¼   SHARES_COMPLEX 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
H2AX MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21676867 14519663 18001824 21293379 16427009 16377563 18583988 21622030 18001825 12607005 19234442 20159462 15201865
MDC1 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 15201865 20460517 23115235 14519663 18001824 18678890 19804756 18583988 19230643 12607003 12607005 20224574
PLK1 MYC â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
PLK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 25915540 23887393 19622404 19686080
NBN XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
NBN RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RIF1 RAD50 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC6 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 RIF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H2AX RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC6 H2AX â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387