Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CD247 VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
FCGR2A VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGHG1 VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
CD3G VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
FCGR3A VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
SYK VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
FCGR1A VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGHG3 VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGHG4 VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
PIK3R1 VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7033842 16982329
VAV2 VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9705280 11804587
IGKC VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGHG2 VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
VAV1 VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9705280 11804587
PIK3R2 IGKC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGKC CD247 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1314888 2474607
IGKC PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGKC VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGKC VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGKC IGHG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11183784 5213535
IGKC PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
PIK3R2 IGHG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG2 VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGHG2 PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG2 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG2 FCGR3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1314888 2474607
IGHG2 VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGHG2 PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG2 CD247 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1314888 2474607
IGHG3 FCGR3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1314888 2474607
IGHG3 VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGHG3 PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG3 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PIK3R2 IGHG3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG3 VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGHG3 PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG3 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG3 CD247 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1314888 2474607
IGHG4 PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG4 CD247 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1314888 2474607
IGHG4 PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG4 VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGHG4 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG4 FCGR3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1314888 2474607
IGHG4 VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
PIK3R2 IGHG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG1 CD247 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1314888 2474607
PIK3R2 CD247 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
VAV1 CD247 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
CD247 CD3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CD247 PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
CD247 VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
CD247 PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
CD3G CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
PIK3R2 CD3G â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
CD3G VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
CD3G VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
CD3G PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
CD3G PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
VAV1 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621483 5220979
CRK HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIK3R2 FCGR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR1A PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR1A PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7517665 8657103
FCGR1A PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7517665 8657103
FCGR1A PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR1A VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
FCGR1A VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
FCGR1A PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
PIK3R2 FCGR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR2A PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR2A VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
FCGR2A PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR2A PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7517665 8657103
FCGR2A PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7517665 8657103
FCGR2A VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGHG1 FCGR3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1314888 2474607
PIK3R2 FCGR3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR3A VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
FCGR3A PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR3A PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR3A VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
FCGR3A PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIK3R2 IGHG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG1 VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGHG1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IGHG1 VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
IGHG1 PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
PIK3CA PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
PIK3CA SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
SYK PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9720763 10592173
PIK3CA VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11094073 9891995
PIK3CB SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
PLCG1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
PIK3R1 PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
VAV1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 11331248
PIK3R1 VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 11331248
VAV1 SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
VAV1 VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9705280 11804587
SYK PLCG1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 8657103
R51A1 IGHG3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
R51A1 IGHG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CAH8 IGHG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CAH8 IGKC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
AL3A1 IGHG3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ALDH2 IGKC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
SNX27 IGHG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SNX27 IGHG3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SNX27 IGHG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ALDH2 IGHG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
C1R C1QA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 2372546 10878362
CAH8 IGHG3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CAH8 IGHG1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ALDH2 IGHG3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ALDH2 IGHG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
ELMO2 DOCK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32203420 11703939
C1QC C1QB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12960167 28325905 21054788 16189514
FCGR2A SYK â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
PIK3R1 PIK3R2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
IGHG1 IGKC â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12552112 15174051 11183784 1522589
CRK ELMO2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 31980649
CRK PIK3R1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
C1QB C1QA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14681455 12960167 21054788
C1QC C1QA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14681455 12960167 28325905 21054788
C1QA C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1QA C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1QA C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1QB C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1QB C1S â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QB C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1R C1QB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QB C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1S C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1S C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1QC C1S â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1S C1R â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 2372546 9477945 31749804 2387866 10878362 28514442 12788922 10092586 17996945
C1R C1QC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1R C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1R C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1R C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
IGKC PLCG2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
IGKC FCGR2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7718892 2529342 7521687
IGKC PLCG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
IGKC SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
IGKC C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
IGKC C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
IGKC C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
IGHG2 PLCG2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG2 FCGR2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7718892 2529342 7521687
IGHG2 PLCG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG2 SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG2 C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
IGHG2 C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
IGHG2 C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
IGHG4 C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1QC C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
IGHG1 C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
IGHG3 C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
IGHG3 PLCG2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG3 C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
IGHG3 C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
IGHG3 SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG3 FCGR2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7718892 2529342 7521687
IGHG3 PLCG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG4 PLCG2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG4 FCGR2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7718892 2529342 7521687
IGHG4 SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG4 PLCG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG4 C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
IGHG4 C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1QC C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1QC C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
IGHG1 C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
IGHG1 C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
PLCG2 CD247 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
PLCG1 CD247 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
CD247 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9295038 7761456 7522230
CD3G PLCG2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
CD3G PLCG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
CD3G SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG1 FCGR2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7718892 2529342 7521687
FCGR3A PLCG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
FCGR3A PLCG2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
FCGR3A SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG1 PLCG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG1 PLCG2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
IGHG1 SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
PIK3R2 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22402981 8596638 11733063
SYK PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15536084
PLCG1 SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
C1QB C1QC â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
ELMO1 DOCK1 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 12134158 5215575
SYK VAV1 â—¼   PHOSPHORYLATION ✅ + 0.92 0.92 Signor 11331248
PLCG1 SYK â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
PIK3CB PIK3R2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PIK3CB PIK3R1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
DOCK1 ELMO1 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
C1QA C1QC â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
C1QA C1QB â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
PIK3R1 PIK3CA â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20018188 7383613
SYK VAV1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
C1R C1S â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PIK3CA PIK3R2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
DOCK1 CRK â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 11369773 8657152 26344197 31980649 8662907 17515907 12615911 15673687 10559471 17474147
PIK3CA PIK3R1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CD247 VAV3 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
PLCG1 VAV3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11094073 10592173
SERPING1 C1S â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9882449 17488724 3756141 28742139 6604523
IGKC CD3G â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
IGKC FCGR1A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
IGKC SYK â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18818202 7592958 7538118 8163536
IGHG2 SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
IGHG2 FCGR1A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
IGHG2 CD3G â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
IGHG3 SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
IGHG3 FCGR1A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
IGHG3 CD3G â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
IGHG4 CD3G â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
IGHG4 SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
IGHG4 FCGR1A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
CD247 SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
CD247 SYK â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10358164 10562324 11353765 11449354 12393695 12731048 15081523 15099567 18768831 20814939 21059766 2139103 23414611 24445665 7523143 8344348 8478617 8551221 9603467 9625766 9738502
CD247 VAV2 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
CD247 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
IGHG1 CD3G â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
CD3G SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
CRK DOCK1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11146654 12094222 12432077 14697347 15308668 16000375 16076871 18835194 22464172 9808620
CRK DOCK1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11146654 12094222 12432077 14697347 15308668 16000375 16076871 18835194 22464172 9808620
CRK PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRK VAV1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 15308668 16000375 16076871 18835194 22464172
PIK3R1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
CRK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
CRK DOCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 9591773 35044719 17515907 10559471 11369773 9808620 10592173 15673687 12615911 8662907 17474147 8657152
CRK PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 35044719 19380743 25814554 11418612
IGHG1 FCGR1A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
FCGR1A SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
SYK FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9280292 9632805 11141335 15136586 8756631 9295288 8663460 9268059
IGHG1 SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
PIK3R1 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8596638 25241761 20713702 27107012 11733063 21825134 32814053 26496610 8139559 14729945 10358930 14665640
SYK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16921024 15536084
PIK3R1 PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17474147 25241761
VAV1 PLCG1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11007481 8986718 10395673 9099726
VAV1 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
SYK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17081983 19690332 8627166 16497976 15592455 16126727 17389395 19534553 1689310 20068231 10592173 16153436 16038803 1708307 7682059 15144186 9697839 7831290 7744830 12601080 8885868 8657103 17016520
VAV1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 11340169 10849438 22952938 9099726 12626562 12917349 12165654 16713569 25539813 8673706 19909365 7518558 10077632 11278486 26552706 10395673 12885870 12573241 8629002 11526404 10898494 25355530 17050525 10592173 11698448 10646608 11094073 11994416 20189481 12670394 9550384 12616499 22513334 10679059 23109003 9891995 11007481 12740575 17540168 11804587 8630736 17054426 11754814 8986718 9438848 11080163 29145629 12941616 10714681 14764585 15169881 26192618 22786724 8226994 15010370 12094222 8189062 16887996 11709089 16467851 24243840 12186560
VAV1 PLCG2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11007481 8986718 10395673 9099726
VAV1 PLCG2 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
SYK PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771181 19783684 12470302 16449524 14656219 10469124 10933389
VAV1 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 8900182 7518558 23331499 12573241 8629002 23180781 11331248 11262396 10592173 16189514 10092764 8630736 8986718 29145629 9151714 16546099 8809042 24243840
SYK VAV2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15345594 11262396 10592173 10749872