C3
|
CD55
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
6238120
8786315
|
STAT5A
|
IRF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9341115
9806359
|
MASP1
|
C4B_2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10946292
9087411
|
MASP2
|
C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11907111
11527969
|
MASP2
|
C4B_2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11527969
17204478
|
MASP2
|
C4A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17204478
22949645
|
CFI
|
C4BPB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
293746
702059
|
IGKC
|
IGHG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11183784
5213535
|
C4BPA
|
CFI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
293746
702059
|
CFI
|
CR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
6214588
1386357
|
C4B_2
|
CD46
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12055245
2481448
|
C4A
|
CD46
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12055245
2481448
|
CFI
|
CD46
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
6214588
1386357
|
CD55
|
C4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
6238120
8786315
|
CFI
|
C4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
293746
702059
|
CFI
|
C4B_2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
293746
702059
|
CD55
|
C4B_2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
6238120
8786315
|
MBL2
|
CR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23460739
29563915
|
CR1
|
MASP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23460739
29563915
|
C1R
|
C1QA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
2372546
10878362
|
CFHR1
|
C3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
27814381
|
C1QC
|
C1QB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21054788
16189514
12960167
28325905
|
TBP
|
REL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
8413269
16713569
|
MASP1
|
MASP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23785123
10878362
|
MASP2
|
MBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
MASP1
|
MBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
IGHG1
|
IGKC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15174051
1522589
11183784
12552112
|
C1QB
|
C1QA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14681455
21054788
12960167
|
C1R
|
C1QA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10904115
15388251
761607
|
C1QC
|
C1QA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14681455
21054788
12960167
28325905
|
C1QA
|
C4B_2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C1QA
|
C2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
C1QA
|
C4A
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
MASP1
|
MBL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11290788
32041782
20956340
27104295
10878362
21035894
19939495
22854970
18177377
25579818
|
MBL2
|
MASP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11290788
32041782
27104295
10878362
15117939
18177377
29209066
|
C4A
|
MBL2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C4B_2
|
MBL2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C2
|
MBL2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
C3
|
CFI
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6607952
21788512
2971659
|
C1R
|
C1QC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10904115
15388251
761607
|
C1QC
|
C1S
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10904115
15388251
761607
|
C1QC
|
C2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
C1QC
|
C4B_2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C1QC
|
C4A
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C1R
|
C1QB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10904115
15388251
761607
|
C1QB
|
C1S
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10904115
15388251
761607
|
C1QB
|
C4A
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C1QB
|
C4B_2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C1QB
|
C2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
C1S
|
C1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
31749804
10092586
2387866
9477945
33961781
10878362
2372546
12788922
17996945
|
C1S
|
C4B_2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C1S
|
C4A
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
CTCF
|
C1R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22951020
|
C1R
|
C2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
C1R
|
C4B_2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C1R
|
C4A
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C2
|
MASP1
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
C4A
|
MASP1
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C4B_2
|
MASP1
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
MASP1
|
C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11907111
10946292
11527969
|
MASP2
|
C4B_2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
MASP2
|
C2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
MASP2
|
C4A
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
IGHG1
|
C2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
IGHG1
|
C4A
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
IGHG1
|
C4B_2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C4A
|
CR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10531307
11694537
293688
|
C4B_2
|
CR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10531307
11694537
293688
|
CFI
|
CR1
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6607952
21788512
2971659
|
IGHG4
|
C4A
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
IGHG2
|
C4A
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
IGHG3
|
C4A
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
IGKC
|
C4A
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C4A
|
COLEC11
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C4A
|
COLEC10
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
IGHG4
|
C2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
IGHG2
|
C2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
IGKC
|
C2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
IGHG3
|
C2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
C2
|
COLEC10
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
C2
|
COLEC11
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6019133
12396008
10925294
|
IGKC
|
C4B_2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
IGHG2
|
C4B_2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C4B_2
|
COLEC11
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
IGHG3
|
C4B_2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
IGHG4
|
C4B_2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C4B_2
|
COLEC10
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15199963
14280442
12396008
|
C1QB
|
C1QC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
907.0
|
0.9
|
STRING
|
36370105
|
C3
|
CR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
C1QA
|
C1QC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
C1QA
|
C1QB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
C1R
|
C1S
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
C3
|
CFHR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
C3
|
CD46
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
C3
|
CFI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
MBL2
|
MASP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
22607836
9087411
20956340
22854970
10878362
21035894
25579818
27104295
19939495
32041782
|
MBL2
|
MASP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11290788
9087411
15117939
10878362
27104295
22607836
|
CFI
|
C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16023208
1401896
26806831
9291131
8648130
2141838
|
C3
|
CR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10382758
2551147
9988761
2141838
|