Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CRK ARHGEF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CEBPE MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12947005
ERBB2 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB2 SEMA4D â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18025083 15210733
KRAS ERBB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
NRAS ERBB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
HIF1A RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19132225 20001745
MET SEMA4D â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18025083 12198496
MYC PLXNB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18281035 16173081
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
PLXNB1 RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11035813 11937491
SEMA4D PTPRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10648410 7029321
RAC1 SEMA4D â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11035813 11937491
VCAM1 RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MYC HIF1A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15071503 28205554 28628118
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ARHGEF11 PLXNB2 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
MET CRK â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24728074 24828152
ARHGAP35 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 1894621 10873807 32203420
MYC MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
SEMA4D MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12198496
MYC NRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PLXNB1 RND1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ARHGEF11 SEMA4D â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12220504 15210733 12196628 12730235
ARHGEF11 ERBB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12220504 15210733 12196628 12730235
ARHGEF11 RND1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12220504 15210733 12196628 12730235
SEMA4D ARHGEF12 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12220504 15210733 12196628 12730235
RND1 ARHGEF12 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12220504 15210733 12196628 12730235
ERBB2 ARHGEF12 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12220504 15210733 12196628 12730235
MYC ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20920219 21627565 7906953 23421821 20716114
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
HIF1A MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16099863 17028975
SEMA4D PLXNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11937491 20877282 27533782 24043639 11245885 12198496 10520995
SEMA4D PLXNB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 27533782 11245885 26633812 15330859