Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CFTR RHOQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15546864 11162552
KRAS ERBB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
NRAS ERBB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
SP1 ILK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19176380 24361375
SP1 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8887648 19994725
SP1 PRKCB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12105191 20179320
RAC2 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB DHCR7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PRKCI RHOJ â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RAD18 MSMO1 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
EP300 RUNX2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
SP1 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10651903 34252870 16478997 11030335 11517158 15647279 17623675 17906698 28425985 32115405 31536933 12200149 24530506 23714681 10362258 22415975 16734381 19062177 10899165
SP1 AXL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18522535 11953011 20977427
EP300 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20851880 22298955 12697832
SP1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12039077 14962081 15249123
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
RAD18 DHCR7 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
PRKCB ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 17570479 12040186 19568798 15567848 14585353
PRKCB FLT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
SP1 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19716432 20971080 20179320 24458133 18068676 17449871 15462672 21696544 15330762 22511764
SP1 SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 18068676 10224053
RAD18 ERBB2 â—¼   KO_DOWN_REGULATES ✅ - -1.15 1.14 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368