Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TERT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18775701 6742757
RPS6KB1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
MXD1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17998413 19526459
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
MAX CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11511535 10508165
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
CTNNB1 ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11572874 12095419
VDR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11470825 23331499
ZBTB16 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
TP53 ID2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16557594
ZBTB16 ID2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19723763
MYC INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799123 1917937
TP53 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12392301 22242153
MXD1 MAD1L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12876282 19526459
TP53 MAD1L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12876282
TP53 MAD1L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
MAX MAD1L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10229200 7954804
TP53 MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10529175 9724739
MAPK3 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
MXD1 MAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8649388 8637719
MAX TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7969121 10348347
MAX PDLIM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10074148 17546492
MXD1 UBTF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15282543
PDX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11687580 17317781
MYC UBTF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15282543
STAT3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22943793 15810077
MYC TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9988278
MYC ODC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11139609
MYC UBTF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21150319 20195357
TP53 ODC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 PDLIM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22266808 15829976
RPS6KB1 UBTF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14612424
SIN3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 26181367 22028823
TCF7L2 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18602747
TP53 TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14990988
ZBTB16 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24821728 24821727
TP53 TRRAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12138177 11779500
TP53 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
BRMS1 HDAC2 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
MYC SMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
SIN3B SIN3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
KDM5A SIN3B â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
MAX SIN3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649 33961781 29028833
BRMS1 SUDS3 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
SIN3A BRMS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21258344 14581478 15451426 23390556
MYC TERT â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28205554 28628118 32140074
HDAC1 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
MAX TRRAP â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
HDAC1 SAP130 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
MYC SIN3B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24951594 30415952
SIN3A ZBTB16 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MYC HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 17314511 30415952 20195357
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HDAC2 SIN3B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
HDAC2 SAP30 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
MYC TRRAP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
STAT3 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24287565 12147685
TP53 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15383401 20332115 21478913
TERT CTNNB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19571879 11532957 21654818
STAT3 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20830236
MYC CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10229837 11145693
SIN3A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12724404 24981860 14593184 26496610 11102443 17827154 10220385 14647463 9885572 15695521 12398767 26344197 21258344 9804427 16331260 12091390 9150133 11602581 10640275 12920132 9790534 17643391 12943729 19182791 25314079 12374985 28514442 26949739 10444591 11931768 11171972 17956988 12453419 15451426 23752268 11784859 18059533 20585571 9520398 11118440 17962807
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
MAPK3 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
TRRAP MAX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9708738 20946988 29028833 12660246 10611234
MYC MXD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8649388 10508165 8224841
SMC3 MXD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9528857
RPS6KB2 MXD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18451027
TRRAP MYC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 12077335 17353931 21150319 32140074 16705173 9708738 29467282 11839798 30415952 20946988 17314511 11511539 19818711 12660246 10611234
STAT3 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16107692 23874455 20043094
TERT TCF7L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19571879 11532957 21654818
TP53 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16462763 16651407 18431400
BRMS1 HDAC1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
HDAC1 SAP30 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
HDAC1 SUDS3 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
HDAC1 ZBTB16 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
SAP30 SIN3A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
BRMS1 SIN3A â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
SIN3B SUDS3 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
HDAC1 SIN3B â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
MAP2K1 MAPK3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SIN3A SAP30 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10444591 12724404 33961781 9651585 11118440 24981860 21258344 9790534 11283269 26496610 12453419 15451426 11784859 16820529 21676866 11390640 9702189
SAP30 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 26496610 11390640 9885572 9651585 15235594 21258344 12788099 16713569 9790534 11283269 16820529 28514442 18193082 10444591 15451426 23752268 11784859 11118440
TCF7L2 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 11713475 5214798
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
SIN3A HDAC2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12724404 16254079 12082111 24981860 17827154 22493095 9885572 12398767 26344197 21258344 9804427 12493763 14749338 12091390 12943729 25314079 26949739 12453419 15451426 23752268 9150134 18059533
MXD1 SIN3A â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
SIN3A SUDS3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
CTNNB1 TCF7L2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MAX MYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
INS AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 29432553 23912456 11679435 23866690 17335965 24646332 23798298
AKT1 TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 25999477 22366458 10224060 17570479 22902867 15843522 18775701
AKT1 MXD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18451027 19526459
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
AKT1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11943559 23331499 25241761 21071413 12183455 15149849 11438723
BIRC2 MXD1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 15665297 17301840 18082613 21133840 21232017
CCND2 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
MYC CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7526316 11511535 10508165 9339900 15988028 20857481 11060032 14519204 14660677 10956386 21790895 11264343
MAX CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
MYC CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8425218 15121849 11602341 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
TCF7L2 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
CTNNB1 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
MYC CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9632747 19176757 23364919 10523846
VDR CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22213313 16061479 16804902
HDAC1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20580679 19182791 21685935 21184735 24424621 18794357
HDAC2 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15169839 17615296 25241761 22796940 20818389 21685935 15388328 20519943 12508111 11309385 17018611 22514743 19597490 14673164
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
CDK7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17591690 11709713 12064478 1088347 16083285 9372954 11483158 9620776 10348343 10884347 16552184 9315650 11007451 9571186 10747897 17898864 1454855 11585729
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
TCF7L2 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24214913 14706452 19347947 24317174
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
CTNNB1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17145710 9488439 11713475 12446687 17143293 27902311 16569639 22014570 16724116 11955446 16442529 26350900 19202075 17050667 20126258 22056988 16306047 17914096 19443654 18391971 21670201 22155184 10080941 17283121 16230076 22304967 16630820 15684397 11713476 12861022 19304756 20492721 19816403 18772112
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
CTNNB1 ID2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15252039 19751508 7542250 17615296 8666229 11708773 11967263 11955436 22270359 16940750 12051714 15181457
STAT3 CXCR4 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
HDAC1 TCF7L2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15653507 25241761
MYC HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1534087 14519204 1562593 10446203
MYC ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12447693 12695333 12824180 18437010 18483244 12545167
PDX1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 134.0 1.0 Omnipath 10636926 10567373 19275670 15664999 10748090 10393088 10440129 15944145 17312465 9453241 23796517 15180990 12150938 16148004 12426319 12099699 9199333 17991720 22968147 23737644 11423476 23153982 7575438 17512083 15743769 10331405 16461554 22974359 17299038 18951876 24472553 16901969 9604866 10720084 20943817 18252719 15001545 7491105 12684063 22172402 8986763 20886630 22028710 15993959 11309388 11428722 10924326 16675598 15862113 12783165 10385428 11316746 9252422 16141209 16887799 10629047 15885879 8988180 20007976 10868963 10545531 22150363 9873045 20531294 16055439 18274620 11477691 9649577 12606496 11834725 10545530 12665509 15166251 8697303 23853095 12475772 20339896 7568086 21393239 17150967 16280646 17259388 19264802 10485916 15664997 8922372 23927931 22570331 21540283 22167125 10426567 21335550 21278380 11003654 17299998 23703573 8483904 15496408 18360684 21063109 17449132 7708065 22253604 10585868 16543365 10905482 1944296 11181516 7937976 21076579 18772243 8954967 17927952 7901001 23434589 23382704 14550306 15790780 9637677 10672004 11457885 12193567 17569705 12130581 17785922 20811152 17627512 17706592 8799146 17991758 11549279 19689288 9230347
MAPK3 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 8506364 8618896 8226850 7597029
LCK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11404481 9484840 9344858 18070987 10815799 16189514 10825200 25814554
MAP2K1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9305919 7719937 7568001 10602027 12681450 7719938 7544001 7528668
MAP2K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 9694850 17081983 11319218 18799465 17389395 9447970 15342917 8226933 15851026 12270934 12644307 11242034 1381507 17906627 9677429 11986622 8376945 7992057 11948414 7687743 9731057 19197339 11704645 7565670 12750173 12932319 8626767 23331499 12048245 7559390 17272394 15811950 26987942 19494114 18669648 18691976 17192257 8388392 7898932 16464493 19369195 12920017 15466214 19690332 11134045 19534553 10995751 7867743 8223433 8248196 10567369 19933846 17563371 1518847 11730323 18983981 16186792 16135787 15951569 19058874 15212693 10748187 9560161 9925641 9733512 18083107 11104681 9006895 17569879 21071413 7731720 1330321 93330262 19541618 15466476 12925710 11971971 11136732 11118451 10746662
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MAPK3 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 15547943 20080742 14967450 12040186 15173823 12697810 11940578 16227978 12738796 16039586 9722592 17255949 15774499 15187187 19541618 19091303 19565474 17052211 11279232 9271440 18039929 18775330 10601235 12792650 11431469
MAPK3 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 15342917 18039929 12832467 23109003 8387505 14966081 9915826 21071413 17906627 9430688 11335727 18988627 11532940 10411321
MAPK3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18463697 9155018 21071413 32482868 18988627 15210690
MAPK3 UBTF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 11741541 19007248 18669648 20068231
MAPK3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 18448488 19413330 11335711 9343414 23331499 15465816 25584415 12576423 11350938 20068231 12681450 10417333 12763138 9872331 18988627 11780390 18491316 18669648 11404481 10521505 18691976 19723038 20058876 14551213 10446219
MYC MAX â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MAX MXD1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10606235 11031250 11274345 11274400 14673140 15121849 16908182 18222063 18754863 19846528 2006410 21790308 22381618 22723415 8425218
MYC MAX â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508165 15665468 8385351 8649388 8521822 22384171 1406956 17341548
MAX ODC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9294616 9343440 12565711 8637719 19578763 7822433 7478599 8356088 18806825 8262968
MAX MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 17145710 16287840 25609649 12821782 16606833 16596619 21807113 25522242 20691906 19578763 24951594 8224841 17643117 9528857 12391307 16705173 21150319 10229200 21988832 15572685 9680483 2006410 17314511 14749374 12553908 17289033 17418410 19623651 12824180 17157259 12584560 26496610 20946988 20936779 8425218 23816886 17353931 10319872 17471507 18003922 16140957 20382893 12660246 8266081 7565735 32296183 10465786 26267534 17072308 27705803 9184233 18620061 10918583 17700062 10593926 10611234 16352593 9708738
MXD1 ODC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 8637719 12565711 19789310
RPS6KB1 MXD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18451027
RPS6KA1 MXD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18451027
STAT3 MYC â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
TCF7L2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 12095419 19561604 19895682 15579438 26947016 16204248 12799378 12907606 17360646 9727977 21533051 20133699 15576399 19784072 24447505 12591729 20818421 18852287 11973610
STAT3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19289167 17204573 18184402 22317895 20067773 15184887 15469392 10464281 9325164 20654581 21573184 17959148 22349830 9874564 20581311 19259613
MYC TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 76.0 1.0 Omnipath 16287840 15655249 12821782 16880523 21807113 19047367 14744757 16489011 12941894 10786671 14519204 19360348 10723141 12970752 15595642 18365874 15665468 22207128 14611815 10022128 15226182 11274400 10491298 11606399 17070091 19787269 19806010 20454512 19762557 21132266 21553143 18818322 10914736 17934056 19148473 11435602 12695333 12802280 21995449 11287602 12044867 21627565 23860446 17942561 19649288 23759068 10606235 12807729 15958520 17141225 20723213 16402390 16785237 18093727 21855630 24705139 18367227 14563552 16205635 19003324 9988278 17706770 17967894 18226852 18754863 10637317 18586674 14612409 19912441 15371341 11916966 12646176 11279234 18158869
MYC ODC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 26766587 8637719 9626477 19578763 8356088 14519204 17520086 11331080 7895500 12435808 19789310 10581008 9090124 12565711 20603835 15519656 16706751 7478599 16439861 9190900 8242794 2109024 11306486 7822433 21874531 11050389 9293942 9294616 8297793 15843384 7787888 9371770 10380878 20410304 18806825 8262968
MYC TRRAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17848523 23775087 11511535 20194507
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
TCF7L2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
ZBTB16 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14645547 19723763 19444914 18246121
TRRAP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 17353931 11511539 12660246 20194507 9708738
TCF7L2 TRRAP â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
TP53 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15656906 12807729 15067344 15734740 11064449 15262117 16234237 10778946 15371422 22496369 18754863 19649288 19787269
TP53 INS â—¼   KO_DOWN_REGULATES ✅ - -1.53 1.52 PKG 28854368