Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ROBO1 SRGAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11672528 26365803
ABL1 SOS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SOS2 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
HRAS ABL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15886098 5217726
NCK1 ABL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CD9 SRGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CDH1 EPCAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DCC RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
HRAS EFNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2201922 7478585
HMGA1 ROBO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NCAM1 SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12700044 2809592
NCK1 RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
RAC1 NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766742 16189514
NCK1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766742 16189514
NFIA ROBO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
NFIA NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
NFIA SLIT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
NFIB SLIT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
NFIB ROBO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
NFIB NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
NFIX ROBO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
NFIX SLIT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
ROBO1 TUBB4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
USP33 ROBO1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 25242263 19706539
SLIT3 ROBO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19741192 30288875
SOS2 HRAS â—¼   GTPASE_REACTION ✅ + 0.8 0.8 Signor 21779497
NCK1 NCK2 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
ROBO1 ROBO4 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
NCK1 SOS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 17474147
FNBP2 RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 20810653
RHOB DAG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
GDPD5 ROBO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB MYO9B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB ROBO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
NCK1 SOS1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ABL1 ENAH â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
SOS1 KRAS â—¼   GTPASE_REACTION ✅ + 0.82 0.82 Signor 25624485
ROBO1 UBP33 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19706539 29533940 30896071 19684588
NCK2 ABL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NCK2 BRK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ABL2 NCK1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25241761 17474147 33961781
NCK2 SOS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10026169 16713569
ROBO1 USP33 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CDH1 EPCAM â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EPCAM ST14 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
FNBP2 ROBO1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26365803 11672528
ENAH VASP â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SRGP1 ROBO1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11672528 32203420
NFIB NFIA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26871637 35140242
EVL VASP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ENAH EVL â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDH1 ST14 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SLIT2 ROBO1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10102268 17848514
VASP ENAH â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 21398369 26186194 28514442 34079125
VASP EVL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 21398369 26186194 28514442 34079125
CAP2 CAP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 8761950 16189514
ABL1 ABL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27229929 12569093 15735735
DAG1 NCK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11724572 17474147
NCK2 EFNB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12206665 16713569 15764601 12606549
NCK2 NCK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194 31980649
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
SRGAP2 SLIT2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16857672 11672528 21655271
SOS1 KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25624485 23331499 16293107
NFIB NFIX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 35140242 9099724 26871637 28514442
NFIB NFIX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9099724
SLIT1 ROBO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21600986 30547091
SRGAP3 SLIT2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16857672 11672528 21655271
SLIT2 SRGAP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16857672 11672528 21655271
SOS1 HRAS â—¼   GTPASE_REACTION ✅ + 0.9 0.9 Signor 23132018
ROBO1 SLIT3 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
SOS1 HRAS â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 17084389 5219305
NCK1 ABL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12379115 7926767 10372803 11494134 10967110 17474147
ROBO1 SLIT2 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
HRAS SOS1 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
SOS2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17496910 12628188 17673906 21779497
ABL1 ENAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17101133 20841568 12672821
ABL1 ABL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12569093 15735735 20841568
ABL1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15039778 20841568 8112292
ABL1 NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10372803 23331499 22327338 11494134 10967110 12379115 17474147 20841568 7926767
ABL1 ROBO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17618275 10892742 20841568
CDH1 CDH2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDH1 CDH2 â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CXCL12 CXCR4 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
CXCL12 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24023874 10233851 10699158 11859124 22633458 18648536 18448868 8752280 30476826 12714578 16725153 9712844 8752281 9551924 21757744 19837984 25495026 26582643 16626895
FGFR4 SOS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
NRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS SOS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
SOS1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12628188 10208427 16713569 10913276 23331499 18454158 15507210 10592173 17673906 17496910 26721396 20133692 19141281 23132018 11560935 9447984 9690470 17084389
KRAS SOS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
NCAM1 ROBO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16226035
NCAM1 ROBO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16226035
NCK1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 10026169 10206341 7862111 17474147 8810325
NRAS SOS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
SOS1 NRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 7923364 11560935 9690470 21779497 8493579
SLIT2 ROBO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17848514 10102268 31217826 1010226810102260
SLIT1 ROBO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21600986 10433822 16713569 14761655 1043382210433820
SLIT3 ROBO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 31180321 11754167
SLIT2 ROBO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 16226035 29317497 10102268 15130495 31217826 14761655
SLIT2 ROBO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12941633 15894287 31217826