Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
BABAM1 BABAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
BEGAIN DEF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CDC42EP1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CDC42EP1 PLSCR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CDH1 EPCAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
XRCC4 DEF6 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
BRCC3 DEF6 â—¼   PHYSICAL_INTERACTION 809.0 0.8 STRING 36370105
RAPGEF4 RAP1B â—¼   GTPASE_REACTION ✅ + 0.81 0.81 Signor 10777494
EPCAM LAD1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
DEF6 ZFYV9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF6 FOG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF6 FBX11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF6 RBPS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF6 VWA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF6 IP6K1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF6 MIPEP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF6 YAP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF6 PZP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF6 POTEE â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF6 EXTL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF6 INTS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
RCC2 RAC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25074804 12919680
CDC42 RAP1A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
CDH1 EPCAM â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
DEF6 GOLGA6A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
RAP1B CDC42 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 26344197
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
NHEJ1 CDC42EP1 â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
DEF6 KRT31 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
DEF6 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15023524 16189514
DEF6 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15023524 16189514
NHEJ1 DEF6 â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
EXO1 DEF6 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
BABAM1 BRCC3 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
DEF6 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18976935 9490022 9113980 15023524 10816584 17045588 16189514 8836113
LCK DEF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18976935 12923183
LCK PRKCQ â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK PRKCQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22798961 26090489 17548359 10652356
RAP1A RAPGEF4 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16076873 15469846 15334074 16757337
RAP1B RAPGEF4 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16076873 15469846 15334074 16757337
RAD18 DEF6 â—¼   KO_UP_REGULATES ✅ + 1.03 1.03 PKG 28854368
RAD18 CDC42EP1 â—¼   KO_DOWN_REGULATES ✅ - -1.52 1.51 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368