Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
IFFO1 ACAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RNF183 IFFO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RBNS5 IFFO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
F167A IFFO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN331 IFFO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN574 IFFO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
COG5 IFFO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DKK3 IFFO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SNX32 IFFO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TPTE2 IFFO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZBBX IFFO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
IL23A IFFO1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
XRCC4 PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9430729 15194694 22939629 9259561 15520013
LMNA IFFO1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24623722 31548606
PRKDC XRCC4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
LIG4 NHEJ1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
IFFO1 XRCC4 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
XRCC5 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26496610 22404984 15520013 21679440 26446488 26344197 17308091 15941674 28154079 16857680 20711232 19303849 20023628 15758953 20085707 10750018 10446239 33005030 9312071 28345663 12393188
NHEJ1 XRCC5 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
LIG4 XRCC4 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 11163244 12032095 12471202 15385968 15703371 16439205 16697054 17088286 17638872 18077224 19346677 19473888 19546231 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
LIG4 XRCC4 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 11163244 12032095 12471202 15385968 15703371 16439205 16697054 17088286 17638872 18077224 19346677 19473888 19546231 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
PRKDC LIG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15194694 15941674 17570479
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
XRCC5 NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
NHEJ1 LMNA â—¼   KO_UP_REGULATES ✅ + 1.2 1.2 PKG 28854368
XRCC4 LIG4 â—¼   KO_DOWN_REGULATES ✅ - -1.52 1.51 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368