Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
FLOT2 KIF18B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FZR1 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC4 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
INCENP AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218018 16239925
AURKB BIRC5 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19357306 0900833106
NUSAP1 CDCA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12963707
TPX2 CDCA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12389033
FZR1 TPX2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
INCENP KIF22 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CDCA5 TPX2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SUMO2 WRN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19471022 16524884
CDCA8 KIF22 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CDCA8 INCENP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CDCA5 INCENP â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CHAF1A CHAF1B â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
NHEJ1 SUMO2 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
AURKB CDCA8 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
INCENP TPX2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CDCA8 INCENP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
INCENP BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5219326 17099693
AURKB CDCA8 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
BIRC5 CDCA8 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CHAF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PROXIMITY ✅ 0.91 0.91 mint 25281560
CHAF1B H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24981860
H3C2 CHAF1B â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 7219095 19498464
H3C2 CHAF1B â—¼   PROXIMITY ✅ 0.92 0.92 mint 25281560
AURKB BIRC5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CDCA8 BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219326 17099693
CHAF1A CHAF1B â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
AURKB INCENP â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 12925766
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ANAPC4 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
AURKB H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11278789 19007248 17938195 10464286 16457588 12234980 12082625 21282660 15249581 10949293 15108802 16185088 14583461 12588998 15681610 17924679 16222246 15684425 12560483 11856369
BIRC5 AURKB â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB INCENP â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
BIRC5 AURKB â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB INCENP â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 18773538 20619651 26460953 16565220 21554500 19303298 18477699 33067654 27332895 22024163 15316025 24344188 20068231 19357306 22814604 19951914 15249581 25892238 16571674 27512725 11050385 12925766 18669648 15630414 18767990 18691976 17956729 20562864 21051298 32028528 19369195 19995937 20739936 16239925 32356865 20430883
AURKB BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17145710 23955284 21554500 16291752 18477699 12419797 27332895 19357306 14610074 20807437 17457057 29371939 17099693 11516652 24571573 17681274 21051298 19995937 16769825 20430883
BIRC5 INCENP â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
BIRC5 INCENP â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
NHEJ1 KIF18B â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
WRN KIF18B â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
EXO1 KIF18B â—¼   KO_UP_REGULATES ✅ + 1.39 1.39 PKG 28854368
XRCC4 KIF18B â—¼   KO_UP_REGULATES ✅ + 1.95 1.95 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368