Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
POLB WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEFL S100P â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEFL EPS8L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 ANXA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CD3E EPS8L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7213612 17617578
CDH1 EPCAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTSD EPS8L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 CTSD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11865007 10029407
TP53 CTSD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
SPRED1 EPS8L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 EPS8L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRN EPS8L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EPS8L2 TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
EPS8L2 TRIM63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
WFS1 ESRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 S100P â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 SERPINB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
CDH1 ESRP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
AGR2 S100P â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
CFTR EPCAM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
EPCAM ESRP1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
POLB EPS8L2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
H2AFY2 EPS8L2 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
CDH1 EPCAM â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EPCAM ST14 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
ESRP1 ST14 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
NHEJ1 ANXA3 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
CDH1 ST14 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
PTK2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CFTR GRN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26618866 29924966 17110338 31324722
NHEJ1 EPS8L2 â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
TP53 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15383401 20332115 21478913
TP53 EPCAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19141643
PTK2 EPS8L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ABI1 SOS1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10499589 15289329
MDC1 PTK2 â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
PPP1R13L TP53 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PPP1R13L TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17906639 21192816 18275817 16713569 15558054 12524540 23623661
TP53 PTK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24809783 20515733 21355845 21071137 21269258 18493017 17999388 17725966
TP53 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18431400 25241761 15855171 18206965 19857493
TP53 SERPINB5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12011991 15578720 17700520 10692390 17204482
NHEJ1 H2AFY2 â—¼   KO_DOWN_REGULATES ✅ - -1.51 1.5 PKG 28854368
MDC1 ANXA3 â—¼   KO_UP_REGULATES ✅ + 1.64 1.64 PKG 28854368
MDC1 EPS8L2 â—¼   KO_UP_REGULATES ✅ + 1.84 1.84 PKG 28854368
TP53 EPS8L2 â—¼   KO_DOWN_REGULATES ✅ - -1.97 1.96 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
H2AFY2 H2AFY2 â—¼   KO_DOWN_REGULATES ✅ - -3.83 3.82 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368