Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
BACE2 RHNO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
TFIP11 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GOLGA2 TFIP11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TOPBP1 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 8086392 20871591
RAD18 TP53BP1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
BRCA1 RAD18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25184681 29656893 23901102
BRCA1 UBE2N â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
BRCA1 TOPBP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HUS1 RHNO1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
RAD1 RHNO1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
RAD9A RHNO1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
RAD9A HUS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26088138 14624239 14681455 12628935 9872989 11907025 32296183 10777662 10852904 19464297 11994305 28514442 16189514 15314187 11340080 10359610 26186194 14611806
UBE2N RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
RAD9A TOPBP1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
RAD9A RAD1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11907025 25091155 33961781 25602520 10777662 16189514 15314187 26088138 10852904 11340080 10359610 11994305 11572977 26186194 12628935 14611806 28514442 9872989
RAD18 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
HUS1 RAD9A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RAD1 RAD9A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
TOPBP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
HUS1 RAD1 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 15871698 16216273 16697054 16713580 16731526 16805667 16879101 16885023 17102137 17116885 17129768 17296725 17303408 17384638 17395641 17426133 17493829 17582221 17855402 18469862 18543256 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 23507534 8943031 9524127
HUS1 RAD1 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 15871698 16216273 16697054 16713580 16731526 16805667 16879101 16885023 17102137 17116885 17129768 17296725 17303408 17384638 17395641 17426133 17493829 17582221 17855402 18469862 18543256 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 23507534 8943031 9524127
TOPBP1 RAD9A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20724438 11395493 12941802 17006541 22925454 19652550 17575048
UBE2N TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 17349954 17652783 18196958 19203579 19258535 19793861 19793862 19841479 19851286 22771115
RAD18 UBE2N â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368