Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
BACE2 LGALS9C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BACE2 TEX12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BACE2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BACE2 ARFGAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF3 BACE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BACE2 MATK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BACE2 STX11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BACE2 DUSP10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BACE2 LARP4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BACE2 RHNO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BACE2 TCP10L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BACE2 KRT19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BACE2 CATSPERD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12392301 22242153
CLC2D BACE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SIA8D TECT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TECT2 BACE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SIA8D BACE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TM11B BACE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD1E BACE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MPPE1 BACE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CHST6 BACE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
IFNE BACE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HLAE BACE2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HLAE TECT2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AT1B3 BACE2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CC50A BACE2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
GGA1 GGA2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
GGA2 BACE1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12135764 14567678 26053850
APP BACE1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BACE1 GGA1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
BACE2 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10936190 10605825 8764598 15178331 20418918 10931940
BACE1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 30538620 22801501 10677483 20418918 12901838 10531052 10931940 32814053 28923680 28869759 19251705
TP53 NOTCH1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368
TP53 INS â—¼   KO_DOWN_REGULATES ✅ - -1.53 1.52 PKG 28854368