Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MST1 H2BC11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
FOXO3 AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 10102273 5211323
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
MAPK1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8941362
CREBBP FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10973497
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
TP53 HGF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
HGF MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16397249 17667909
KLKB1 MST1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10068459
MOB1B MST1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219739 17347649
TP53 STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17108107 21317932
TP53 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23995788 21317932
TNNC1 TNNI3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
FOXO3 TP53 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
CREBBP FOXO1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
CREBBP FOXO3 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
STK4 RASSF1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
ICAM1 ITGB2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AKT1 STK11 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24412244 28205554 28628118
STK4 RASSF5 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
AKT1 FOXO1 â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 21798082
AKT1 FOXO1 â—¼   RELOCALIZATION ✅ - 0.85 0.85 Signor 18423396
HNF4A FOXO1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12519792 19740748
MAPK1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BECN1 AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 29669822 23112296
STK4 MOB1B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24255178 22863277
AKT1 FOXO1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
STK4 SAV1 â—¼   UP_REGULATES ✅ + 0.89 0.89 Signor 16930133
TP53 H2BC11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21617703 16980608
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
MST1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20028971 16751106 12040186
TP53 HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17216187 18431400 9023107
KLKB1 HGF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10962009 12372819
HNF4A MST1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9886825 8621550 9668124
HNF4A NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17317687 11741883 16479620
MYC ICAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MAPK1 RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
MST1 RASSF5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 16892067 19454690 23792360
MST1 MST1R â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 16892067 19454690 23792360
MYC MST1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24499724 12695333
TNNI3 TNNC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15049709 33961781 12840750 18986304 11904166 12122471 12060657 29997244 7957210 12939162 15134451 16302972 9346285
RASSF1 STK4 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
AKT1 FOXO3 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
AKT1 STK4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 19940129 17932490
STK4 SAV1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
TNNI3 TNNT2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TNNC1 TNNT2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
SAV1 STK4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TNNC1 TNNI3 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RASSF5 STK4 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
STK4 H2BC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16885155 21212262 19747733 16462032 21646345 26759222 28740074 12757711
MST1 H2BC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12757711 21212262
FOXO3 AKT1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
AKT1 FOXO3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
AKT1 FOXO1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
FOXO3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19424579 23517348 21752881 22539004 11278373
AKT1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 90.0 1.0 Omnipath 21440011 10358014 11756412 10358076 31308176 20452955 21798082 11410590 20398329 11311120 11544290 28279977 10217147 15132996 23331499 19216069 11237865 20214616 11463845 16076959 11030146 12228231 9829964 18951090 23180781 17570479 10102273 18593906 17646672 16680151 12456685 18423396 18985696 18988627 17962350 30728292 16670091 18786403 14664696 25241761 16341064 11980723 10358075 2984676 13679577 12560069 10377430 11251083 17680028 2987962 17254970 11864996 20041807
AKT1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 19951971 11756412 11953455 11923280 20452955 21798082 20398329 21329882 10217147 11154281 11994454 23331499 10995739 19216069 20214616 11463845 21775285 20068231 9829964 17570479 10102273 18593906 17646672 16680151 18988627 21621563 15169778 17522590 25241761 23109003 11715018 19188143 15023346 17680028 26192618 11864996
AKT1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 22391560 24526064 29864144 34230470 16224021 26517694
AKT1 MST1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 12919677 14505491
AKT1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 22619175 19369195 19737514 19940129 17932490 23431053 11805089 24872389 23893242 17726016
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
FOXO3 FOXO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19244250 16100571 18202312 23509296 19690465
STK4 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19221179 18786403 21245099 21320536 22898666 29896440 18394876
MST1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18786403 16751106 21320536 29896440
HNF4A FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12519792 19740748
MST1 FOXO3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12040186 16892067 19454690 20028971 23792360
FOXO3 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22412893 22848740
STK4 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 27769056 22898666 18394876 28521392 16751106 18985696
MAPK1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18204439 29445193 22128155 10102273
HPN HGF â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 15324701 15792801 9045658 8346233 1280830 1885621 9346890
TP53 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11818510 16895524
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
HPN MST1 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 24409221 15792801 20228799 21875933 8346233 22087277 1885621
IL10 ICAM1 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10433356 10542212 10623821 10925299 11207245 11438547 11875494 12193690 12811837 12818165 14607900 15282297 15579430 15749903 15833879 16200688 16424049 16713974 17404308 17485448 20184663 20435894 20547845 21115385 21191065 21220452 23124025 23508573 24378531 26755705 9834059
ICAM1 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 4062888 12208882 11279101 16189514 10352278 20187292 14507735 7642561
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 14965474 9765199 15116093 21675959 23443559 10781582 25241761 10446957 10958792 11409876 11709713 21147777 10673501 11551930 15867353 11875057 12091386
MAPK1 STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25679014 25846811
STK11 MARK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 14517247 18691976 14976552
STK4 MOB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18328708 22863277 23431053 21808241
MST1 MST1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 9045873 23331499 22087277 12764615 8062829 9374547 25193665
RASSF1 MST1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21199877 14729613
RAP1A MST1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 10850490 18680434 19454690 19965504
MST1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12223493 11805089
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
TP53 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11131279 11092782 9194524 8637893
RAP1A RASSF5 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 10850490 18680434 19454690 19965504
RAP1A RASSF5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12845325 17145710 15569673
TP53 RASSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23779024 23038753 21364923
RASSF5 RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11857081 16713569 22195963
RASSF1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 20562859 17145710 24366813 26186194 14729613 26578655 24255178 20920251 22683405 15109305 23386615 17598981 21808241 23455922
STK4 RASSF5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20562859 16892067 24366813 24255178 11864565 15109305 16713569 17517604 23455922
RASSF5 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 20562859 16892067 24366813 24255178 11864565 15109305 16713569 17517604 23455922
SAV1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20562859 17145710 24366813 16930133 26186194 24255178 20920251 21084559 23386615 25692647 17517604 23455922
STK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20815019 11430832 17108107 16713569
STK4 TNNI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18986304 22972900